A system for detecting neurological disorders based on an electroencephalogram (EEG) signal is disclosed. The system includes at least one processor and at least one memory storing instructions. The instructions, when executed by the at least one processor, cause the system to access the EEG signal, process the EEG signal to filter for a brainwave frequency band, detect, via an EEG analytic engine, a brainwave pattern from the processed EEG signal based on the filtered brainwave frequency band, and generate, via a synchronization pattern visual generator, a two-dimensional network pattern image of the detected brainwave pattern.

The present disclosure provides methods for receiving distinct electrical signals generated based on a body part, generating a plurality of extracted features based on the distinct electrical signals, identify clinically relevant features from the plurality of extracted features, wherein the clinically relevant features meet a threshold determined based on a clinical outcome.

Disclosed herein are a method and apparatus for analyzing elements inducing motion sickness in VR content. The method includes acquiring objective data based on an experiment using the VR content for measuring VR motion sickness, the experiment being conducted according to a predetermined protocol; acquiring subjective data input from the multiple participants of the experiment; and constructing a database based on the objective data and the subjective data and analyzing the degree of motion sickness induced by each of the content elements of the VR content using statistical information based on the database.

Systems and methods for selective auto-retroperfusion along with regional mild hypothermia. In at least one embodiment of a system for providing a retroperfusion therapy to a venous vessel of the present disclosure, the system comprises a catheter for controlling blood perfusion pressure, the catheter comprising a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration, and a flow unit for regulating the flow and pressure of a bodily fluid, and a regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a temperature of the bodily fluid flowing therethrough.

Devices, methods and systems related to the assessment and therapy of neurological conditions and dexterous hand function in particular. For example, some embodiments can relate to devices comprising a first portion of flexible material and forming a cavity; a second portion non-flexible material; a PCB coupled to the second portion; and wherein a portion of an edge of the first portion is configured to create a semi-hermetic seal with at least a portion of an edge of the second portion and the PCB has connected thereto a pressure sensor, a wireless transceiver, and a power storage unit.

Neural activity in the brain arising from a stimulus is monitored. A stimulus is applied to a target structure of the brain and a neural measurement is obtained from at least one electrode implanted in contact with the target structure. The neural measurement is configured to capture a measure of any late response arising in the target structure, typically being a neural response arising after conclusion of an ECAP, such as in the period 1.5-10 ms after stimulus onset. The late response(s) can be a useful biomarker such as of therapeutic ranges of deep brain stimulation, disease progression, medication efficacy, and intra-operative changes.

A system for enhancing or rehabilitating cognitive skills of a subject includes a wearable optical instrument provided with at least one prismatic lens that diverts a beam of light rays coming from a visual target stimulus to induce a vision perturbation thereof by the subject, and at least one housing seat that rotatably supports the at least one prismatic lens.

Systems, methods, and computer-readable media are described for predicting a neurological injury to a participant in an activity. The activity can be, for example, an athletic activity that involves repeated, high-impact collisions between participants. Sensor data reflecting interactions between participants in the activity is received from various wearable and non-wearable sensors. The sensor data is evaluated in conjunction with a baseline neurological risk profile of a participant to determine a likelihood that the participant has suffered a potential neurological injury. If this likelihood meets a threshold risk level, an onsite request/response test is initiated to glean more information relating to the participant's condition. Response data associated with the onsite test is cognitively evaluated to determine an updated likelihood of neurological injury to the participant and a follow-up action is determined based on the updated likelihood of neurological injury.

A nerve stimulator is provided, and in particular a non-invasive nerve stimulator for peripheral nerves, such as the ulnar and/or median nerves. The stimulator may be fitted proximate the left and/or right arm, wrist or hand of a user, to stimulate the median and/or ulnar nerves using electricity, light, sound, magnetic field, vibration or pressure, or any combination of these stimuli. The apparatus takes the form of a standalone band or clasp, or forms part of a fitness tracker band, watch or smartwatch. The nerve stimulator comprises a stimulus generator, to generate any or a combination of the stimuli mentioned above, an applicator to apply the generated stimulus to the arm, wrist or hand of the user, and a controller to control the operation of the stimulus generator and the applicator. In some cases, for stimuli such as light, sound, magnetic field, vibration or pressure, the generator and applicator may be combined into a single component.

The present invention discloses indicator fluids, reference indicator fluid, and usage thereof, and systems and methods for assessing movement of molecular substances within, to or from a cerebrospinal fluid, brain or spinal cord compartment of a human cranio-spinal cavity. Indicator fluid moving from the cerebrospinal fluid compartment enables measurements of levels of indicator fluid in blood or urine and assessment of the cranio-spinal cavity's ability to remove molecular substances. The indicator fluids may be contrast agents used for imaging, such as by computed tomography imaging, and magnetic resonance imaging, or imaging utilizing radioactive substances by positron emission tomography, single-photon emission computed tomography or scintigraphy. Using these imaging modalities, the invention describes indicator fluids, systems and methods enabling assessment of movement of substances within, to or from a cerebrospinal fluid, brain or spinal cord compartment of a cranio-spinal cavity, and from the human cranio-spinal cavity to lymphatic pathways or kidneys.