Described herein are systems and methods for positioning a radiation source with respect to one or more regions of interest in a coordinate system. Such systems and methods may be used in emission guided radiation therapy (EGRT) for the localized delivery of radiation to one or more patient tumor regions. These systems comprise a gantry movable about a patient area, where a plurality of positron emission detectors, a radiation source are arranged movably on the gantry, and a controller. The controller is configured to identify a coincident positron annihilation emission path and to position the radiation source to apply a radiation beam along the identified emission path. The systems and methods described herein can be used alone or in conjunction with surgery, chemotherapy, and/or brachytherapy for the treatment of tumors.

A method for customizing an interactive control boundary includes positioning a virtual implant model relative to a virtual bone model based on a user input, and extracting reference feature information associated with the virtual implant model, wherein the reference feature information describes one of a point, a line, a plane, and a surface associated with the virtual implant model. The method further includes mapping the extracted reference feature information to the virtual model of the bone, and receiving information indicative of a positional landmark associated with the bone, then estimating an intersection between the positional landmark and the mapped reference feature and generating a virtual boundary based, at least in part, on the estimated intersection between the positional landmark and the mapped reference feature.

An N-M tomography system comprising: a carrier for the subject of an examination procedure; a plurality of detector heads; a carrier for the detector heads; and a detector positioning arrangement operable to position the detector heads during performance of a scan without interference or collision between adjacent detector heads to establish a variable bore size and configuration for the examination. Additionally, collimated detectors providing variable spatial resolution for SPECT imaging and which can also be used for PET imaging, whereby one set of detectors can be selectably used for either modality, or for both simultaneously.

Disclosed is a method of creating a digital abutment design of a customized dental abutment, the including comprising: obtaining a bone scan comprising a digital representation of at least a part of a patient's jaw including the surface of the jawbone; and designing the digital abutment design of the customized dental abutment; wherein the design of the digital abutment design is at least partly based on fulfilling a set of predefined design criteria including the relationship between the digital representation of the jawbone and the digital abutment design.

A diagnostic imaging system utilizing a reduced crystal design pattern is utilized to image a subject and collect event data. The reduced crystal design pattern includes filled crystal locations and empty crystal locations. A processor accounts for empty crystal locations by selecting windows that include nearest neighbor filled crystal locations. The nearest neighbor filled crystal locations include event data which is averaged by the processor and assigned to the empty crystal location. A weighted average based on distance or event strength is incorporated.

There is provided a method for registration of intravital anatomical imaging modality image data and nuclear medicine image data of a patient's heart comprising: obtaining anatomical image data including a heart of a patient outputted by an anatomical intravital imaging modality; obtaining at least one nuclear medicine image data outputted by a nuclear medicine imaging modality, the nuclear medicine image data including the heart of the patient; identifying a segmentation of a network of vessels of the heart in the anatomical image data; identifying a contour of at least part of the heart in the nuclear medicine image data, the contour including at least one muscle wall border of the heart; correlating between the segmentation and the contour; registering the correlated segmentation and the correlated contour to form a registered image of the anatomical image data and the nuclear medicine image data; and providing the registered image for display.

A system is for contrast agent-based medical imaging. In an embodiment, the system includes a gantry of a medical imaging device; a contrast agent injection device; and a support arm including a frame element, a first connecting element and a second connecting element. In an embodiment, the frame element is connected to a stationary support frame of the gantry via the first connecting element such that at least part of the frame element is mounted to be movable relative to the stationary support frame of the gantry, and the contrast agent injection device is connected to at least part of the frame element via the second connecting element such that the contrast agent injection device is mounted to be movable relative to at least part of the frame element.

An image processing device includes: an image data acquisition unit for acquiring SPECT image data of a brain; a brain-region ROI definition unit for defining a brain-region ROI in the SPECT image; a striatum ROI definition unit for defining a striatum ROI in the SPECT image; and a threshold determination unit for, based on counts in the SPECT image's background which is the brain-region ROI except the striatum ROI, determining a threshold for distinguishing ventricles and sulci in the SPECT image; a region distinction unit for distinguishing between a region whose number of counts is smaller than or equal to the threshold and a region whose number of counts is larger than the threshold.

The invention comprises a method and apparatus for tracking and/or imaging impact of a particle beam treating a tumor using one or more imaging systems positionable about the tumor, such as a positron emission tracking and/or imaging system, where resulting tracking/imaging data: dynamically determines a treatment beam position, tracks a history of treatment beam positions, guides the treatment beam, and/or images a tumor before, during, and/or after treatment with the charged particle beam.

A device and methods for performing a simulated CT biopsy on a region of interest on a patient. The device comprises a gantry (22) configured to mount an x-ray emitter (24) and CT detector (26) on opposing sides of the gantry, a motor (28) rotatably coupled to the gantry such that the gantry rotates horizontally about the region of interest, and a high resolution x-ray detector (172) positioned adjacent the CT detector in between the CT detector and the x-ray emitter.