A non-spectral computed tomography scanner (102) includes a radiation source (112) configured to emit x-ray radiation, a detector array (114) configured to detect x-ray radiation and generate non-spectral data, and a memory (134) configured to store a spectral image module (130) that includes computer executable instructions including a neural network trained to produce spectral volumetric image data. The neural network is trained with training spectral volumetric image data and training non-spectral data. The non-spectral computed tomography scanner further includes a processor (126) configured to process the non-spectral data with the trained neural network to produce spectral volumetric image data.

Described here are systems and methods for optimization techniques for automatically selecting x-ray beam spectra, energy threshold, energy bin settings, and other imaging technique parameters for photon-counting detector computed tomography (“PCCT”). The techniques described here are generally based on subject or object size, material of interest, and location of the target material. Advantageously, the optimizations can be integrated with different PCCT systems to automatically select optimal imaging technique parameters before scanning a particular subject or object.

A computer-implemented method is for providing a difference image data record. In an embodiment, the method includes a determination of a first real image data record of an examination volume in respect of a first X-ray energy, and a determination of a multi-energetic real image data record of the examination volume in respect of a first X-ray energy and a second X-ray energy, the second X-ray energy differing from the first X-ray energy. The method further includes the determination of the difference image data record of the examination volume by applying a trained function to input data, wherein the input data is based upon the first real image data record and the multi-energetic real image data record, as well as the provision of the difference image data record.

The present invention relates to an X-ray detector (10) comprising two or more scintillator layers, comprising: a first scintillator layer (20); a second scintillator layer (30); a first photodiode array (40); a second photodiode array (50); and at least one light emitting layer (60). The first scintillator layer is configured to absorb X-rays from an X-ray pulse and emit light. The first photodiode array is positioned adjacent to the first scintillators layer. The first photodiode array is configured to detect at least some of the light emitted by the first scintillator layer. The second scintillator layer is configured to absorb X-rays from the X-ray pulse and emit light. The second photodiode array is positioned adjacent to the second scintillator layer. The second photodiode array is configured to detect at least some of the light emitted by the second scintillator layer. The at least one light emitting layer is 10 configured to emit radiation such that at least some of the emitted radiation irradiates the first photodiode array and at least some of the emitted radiation irradiates the second photodiode array.

An imaging system for inspecting multiple objects includes an x-ray source having a beam width greater than or equal to a threshold beam size. The multiple objects is irradiated by the x-ray source in respective controlled inspection positions. A detection mechanism is adapted to acquire respective images of the multiple objects in the respective controlled inspection positions. The detection mechanism includes one or more detectors arranged circumferentially around a central axis. At least one positioning mechanism is adapted to move the multiple objects into and out of the respective controlled inspection positions.

Methods, systems, and apparatus for performing spectral tomographic reconstruction of an object. The imaging system includes a power source that is configured to provide a variable high voltage. The imaging system includes a distributed X-ray source. The distributed X-ray source includes an array of X-ray emitters that allows fast switching “ON” and “OFF” using X-ray emitter grid electrode. The distributed X-ray sources is configured to generate an X-ray beam with an energy spectrum based on the variable high voltage and uses additional X-ray filters. The imaging system includes a controller. The controller is configured to operate synchronously with the change of the variable high voltage. The controller is configured to control a timing of when to engage an X-ray emitter of the array of X-ray emitters of the distributed X-ray source based on a predefined firing pattern.

The present invention relates to a method for the evaluation of tissue gadolinium deposition that offers advantages compared with known methods. Comparison of different gadolinium-based contrast agents (GBCAs) based on retention, organ distribution, washout and safety is facilitated using the methods of the present invention.

A processor acquires first-direction and second-direction radiographic images captured by emitting radiation in different directions. The processor derives a bone mineral content for each pixel in the bone portion included in the first-direction and second-direction radiographic images. The processor divides the bone portion included in the first-direction and second-direction radiographic images into a plurality of small regions and derives first and second evaluation results for each small region of the bone portion on the basis of the derived bone mineral content.

An image processing apparatus for processing a radiation image, comprises a calculation unit configured to calculate, in a calculation region, a physical amount representing a characteristic of a material, the calculation region being obtained using (a) a specific region regarding a specific material in an image representing the characteristic of the material and (b) a relative positional relationship of a radiation tube, a radiation detector, and an object, wherein the image representing the characteristic of the material is obtained using information about a plurality of radiation energies.

The present invention relates to a device (1) for fractional flow reserve determination. The device (1) comprises a model generator (10) configured to generate a three-dimensional model (3DM) of a portion of an imaged vascular vessel tree (VVT) surrounding a stenosed vessel segment (SVS), based on a partial segmentation of the imaged vascular vessel tree (VVT). Further, the device comprises an image processor (20) configured to calculate a blood flow (Q) through the stenosed vessel segment (SVS) based on an analysis of a time-series of X-ray images of the vascular vessel tree (VVT). Still further, the device comprises a fractional-flow-reserve determiner (30) configured to determine a fractional flow reserve (FFR) based on the three-dimensional model (3DM) and the calculated blood flow.