Methods and systems are provided for adaptive scan control. In one embodiment, a method includes upon a first contrast injection, processing acquired projection data of a subject to measure a contrast signal of the first contrast injection, estimating a time when a venous return to baseline (VRTB) of the first contrast injection is to occur based on the contrast signal, and commanding initiation of a second contrast injection at the estimated time.

The disclosure relates to systems and methods for evaluating a blood vessel. The method includes receiving image data of the blood vessel acquired by an image acquisition device, and predicting, by a processor, blood vessel condition parameters of the blood vessel by applying a deep learning model to the acquired image data of the blood vessel. The deep learning model maps a sequence of image patches on the blood vessel to blood vessel condition parameters on the blood vessel, where in the mapping the entire sequence of image patches contribute to the blood vessel condition parameters. The method further includes providing the blood vessel condition parameters of the blood vessel for evaluating the blood vessel.

A system and method is provided for processing a positron emission tomography (PET) image of a subject having received a dose of a radiotracer that serves as chemical analog of an MC-I inhibitor. Specifically, the processing may includes identifying portions of the at least one PET image that represent MC-I expression levels.

A computer-implemented segmentation method for segmenting a core and a penumbra in a four-dimensional computed tomography perfusion dataset of ischemic tissue in an image region of a patient, includes determining at least one parameter map for at least one perfusion parameter from the computed tomography perfusion dataset; and using the at least one parameter map and the computed tomograph perfusion dataset as input data to a trained function to determine output data, the output data including segmentation information of the penumbra and the core.

Provided herein are methods and systems for making patient-specific therapy recommendations of a lipid-lowering therapy for patients with known or suspected cardiovascular disease, such as atherosclerosis.

A radiographic phantom comprises: a body comprising a wax material or a wax-like material, wherein the body has an x-ray attenuation value that is approximately the same as that of a human tissue; and a plurality of crystalline test objects positioned on or within the body. A method comprises: obtaining a radiographic phantom comprising a body and a plurality of crystalline test objects positioned on or within the body, wherein the body comprises a wax material or a wax-like material, and wherein the body has an x-ray attenuation value that is approximately the same as that of a human breast tissue; performing an operation of the radiographic phantom and using a device; and assessing a performance of the device based on the operation.

The invention relates to a system and a method for determining a characteristic of a blood vessel portion, which comprises blood including a contrast agent exhibiting resonant absorption of x-ray photons at a specific energy. The system comprises a tunable monochromatic x-ray source (21) emitting x-ray radiation, an x-ray detector device (22) for detecting the x-ray radiation after it has travelled through the blood vessel portion. A control unit (26) varies a tuning of the x-ray source (21) to vary the energy of the x-ray radiation emitted by the x-ray source (21), and an evaluation unit (27) determines a tuning of the x-ray source (21) at which nuclear resonant absorption of the x-ray radiation incident onto the blood vessel portion occurs and estimates the characteristic on the basis of the determined tuning. The characteristic may particularly be the blood velocity in the blood vessel portion.

A method is for actuating a medical imaging device for generating a second three-dimensional image dataset including a target region in a region of interest of a patient with a functional impairment. The method includes providing a first three-dimensional image dataset including the region of interest of the patient; identifying the target region based on the first three-dimensional image dataset, a partial region of the region of interest with the functional impairment being determined; determining an imaging parameter for generating the second three-dimensional image dataset based on the identified target region; and actuating the medical imaging device based on the imaging parameter for the generation of the second three-dimensional image dataset.

A system (100) includes a computer readable storage medium (122) with computer executable instructions (124), including: a biophysical simulator component (126) configured to determine a fractional flow reserve value via simulation and a traffic light engine (128) configured to track a user-interaction with the computing system at one or more points of the simulation to determine the fractional flow reserve value. A processor (120) is configured to execute the biophysical simulator component to determine the fractional flow reserve value and configured to execute the traffic light engine to track the user-interaction with respect to determining the fractional flow reserve value and provide a warning in response to determining there is a potential incorrect interaction. A display is configured to display the warning requesting verification to proceed with the simulation from the point, wherein the simulation is resumed only in response to the processor receiving the requested verification.

Methods and systems are provided for adaptive scan control. In one embodiment, a method includes processing acquired projection data of a monitoring area of a subject to measure a first contrast signal of a contrast agent administered to the subject via a first injection, initializing a contrast scan of the subject according to a fallback scan prescription, determining when each of a plurality of zones of the contrast scan are estimated to occur based on the contrast signal, generating a personalized scan prescription for the contrast scan based on when each of the plurality of zones are estimated to occur, and performing the contrast scan according to the personalized scan prescription after a second injection of the contrast agent.