The present invention provides a portable x-ray device with a housing having a side and rear handle, each with triggers and indicator lights in locations suitable for manipulation for use. A trigger is located at each end of each handle and deposed at an angle to be actuated by an operator, with the triggers on one handle controlling a function of the device and the triggers of the other handle controlling a different function. The invention also provides a system including a device with a processor and a wireless device for communication with an external processor.

A system for radiographic tissue density evaluation includes a cassette for exposure to an X-ray source, where the cassette is configured to obtain information to perform intensity standardization of a captured radiographic image of a subject, a calibration bar with a predetermined radiographic signature on or within the cassette to serve as reference for performing the intensity standardization, and a software program to perform analysis on and to provide a display of the captured radiographic image. The cassette also includes a radio-opaque backing with a spatial homogenous X-ray radiographic signature used to estimate a source-detector geometrical inhomogeneity.

Disclosed herein are .sup.18F-labeled compounds and compositions thereof. Also disclosed are methods of imaging estrogen receptor expressing tissues, or methods of identifying cancer lesions using these compounds.

The present invention relates to a method for evaluating a drug involved in angiogenesis. The method includes a drug administration step (A) of administering a drug involved in angiogenesis to a subject having a lesion. The method further includes: an imaging step (1) of performing radiography on a subject in a state where metal nanoparticles are present in a blood vessel or an imaging step (2) of performing fluorescence staining and fluorescence imaging using a dimeric protein; and evaluating the drug using an image acquired in the imaging step (1) or (2).

The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and a real-time camera, either high definition or standard resolution, for the production of organic and non-organic images. The computing device can receive video data from the camera and the x-ray detector and determines, based on the video data, an overlay of the captured x-ray image with the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). In particular, the disclosure relates to a system and method with corresponding apparatus for capturing a real-time image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images with exact orientation of the 2 images.

A positron emission tomography (PET) imaging device (10) includes a plurality of PET detector modules (18); and a robotic gantry (20) operatively connected to the PET detector modules. The robotic gantry is configured to control a position of each PET detector module along at least two of an axial axis, a radial axis, and a tangential axis of the corresponding PET detector module.

A method for internal imaging of biological tissue in a subject by positron emission tomography (PET) or single photon emission computer tomography (SPECT), the method comprising: (i) administering to a subject an imaging agent that includes, at minimum, at least one fluorine-18 radionuclide bound directly or indirectly to a fluorophore, and (ii) imaging internal biological tissue of the subject by PET or SPECT. In further embodiments, the method includes (i) administering to a subject an imaging agent that includes at least one fluorine-18 radionuclide bound directly or indirectly to a fluorophore, and at least one biological entity (e.g., blood cell, peptide, nucleotide, aptamer, targeting agent, antibody, or antibody fragment) bound directly or indirectly to the fluorophore; and (ii) imaging internal biological tissue of the subject by PET or SPECT. In some embodiments, the method further includes simultaneously imaging the internal biological tissue by fluorescence imaging.

A system for use in positioning and restraining an equine hoof during imaging, with at least one panic-releasable connection. The system may comprise an equine boot and an interface plate attached to the underside thereof, a receiver plate attached to a limb placement region of an imaging apparatus, and a placement plate attached to the receiver plate. Further disclosed is use of one or more components apart from the whole system, and methods of use for positioning and restraining an equine hoof during imaging.

A composition for internal imaging of a subject includes an imaging contrast agent and one or more carrier agents that can pass through cellular and tissue membranes. Examples of imaging contrast agents are iodine-based, silver-based, or barium-based. Examples of carrier agents are dimethyl sulfoxide, urea, or an alcohol. Methods for internally imaging a subject using such a composition are also disclosed.

An imaging system and methods including a gantry defining a bore and an imaging axis extending through the bore, and at least one support member that supports the gantry such that the imaging axis has a generally vertical orientation, where the gantry is displaceable with respect to the at least one support member in a generally vertical direction. The imaging system may be configured to obtain a vertical imaging scan (e.g., a helical x-ray CT scan), of a patient in a weight-bearing position. The gantry may be rotatable between a first position, in which the gantry is supported such that the imaging axis has a generally vertical orientation, and a second position, such that the imaging axis has a generally horizontal orientation. The gantry may be displaceable in a horizontal direction and the system may perform a horizontal scan of a patient or object positioned within the bore.