Systems and methods relate to multi-modal imaging of tissue combined with highly focused radiation interventions. The system is a portable multimodal imaging unit that integrates imaging and image analysis. The system can be retrofitted to use with any commercial radiation therapy machine. In one aspect, a system integrates various imaging modalities into a single, coordinated structure. The system integrates X-ray and cone beam computed tomography (CBCT), optical imaging (such as bioluminescent imaging (BLI), fluorescence tomography (FT)), and positron emission tomography (PET) imaging in a single, self-contained structure.

An electromagnetic tracking system including a patient support element and an electromagnetic field generator. The patient support element is superposed relative to the electromagnetic field generator, and the electromagnetic field generator is selectively moveable relative to the patient support element.

A mobile diagnostic imaging system includes a battery system and charging system. The battery system is located in the rotating portion of the imaging system, and includes one or more battery packs comprising electrochemical cells. Each battery pack includes a control circuit that controls the state of charge of each electrochemical cell, and implements a control scheme that causes the electrochemical cells to have a similar charge state. The battery system communicates with a charging system on the non-rotating portion to terminate charge when one or more of the electrochemical cells reach a full state of charge. The imaging system also includes a docking system that electrically connects the charging system to the battery system during charging and temporarily electrically disconnects the rotating and non-rotating portions during imaging, and a drive mechanism for rotating the rotating portion relative to the non-rotating portion.

A system and method for delivering microbeam radiation therapy (MRT) includes a computed tomography scanner (“CT”) configured to generate tomographic images of a subject, or patient, the scanner including an imaging apparatus, a gantry with an opening for positioning the patient therein, an axis of rotation around which the gantry rotates, and an x-ray source mounted to and rotatable with the gantry. The system includes a bed for patient positioning within the gantry opening and a multi-slit collimator removably mounted downstream of the x-ray source for delivering an array of microbeams of MRT to a targeted portion of the patient. Switching between MRT and CT is provided, and MRT modes of operation include a stationary mode, and continuous and step-wise rotational modes.

An imaging system and methods including a gantry defining a bore and an imaging axis extending through the bore, and at least one support member that supports the gantry such that the imaging axis has a generally vertical orientation, where the gantry is displaceable with respect to the at least one support member in a generally vertical direction. The imaging system may be configured to obtain a vertical imaging scan (e.g., a helical x-ray CT scan), of a patient in a weight-bearing position. The gantry may be rotatable between a first position, in which the gantry is supported such that the imaging axis has a generally vertical orientation, and a second position, such that the imaging axis has a generally horizontal orientation. The gantry may be displaceable in a horizontal direction and the system may perform a horizontal scan of a patient or object positioned within the bore.

Systems and methods for integrating a three-dimensional X-ray computed tomography system with an independent sound wave system to determine mechanical properties of tissue using signals from the sound wave system. Methods are disclosed that generate a numerical simulation and take the transmitted wave signals as the optimization objective to estimate modulus distribution of the tissue. Further, the mechanical properties of the tissue are reconstructed based on an inverse algorithm.

A system and method for non-invasive and continuous measurement of cardiac chamber volume and derivative parameters including stroke volume, cardiac output and ejection fraction comprising an ultrawideband radar system having a trans-mitting and receiving antenna for applying ultrawideband radio signals to a target area of a subject's anatomy wherein the receiving antenna collects and transmits signal returns from the target area which are then delivered to a data processing unit, such as an integrated processor or PDA, having software and hardware used to process the signal returns to produce a value for cardiac stroke volume and changes in cardiac stroke volume supporting multiple diagnostic requirements for emergency response and medical personnel whether located in the battlefield, at a disaster site or at a hospital or other treatment facility.

A multi-axis imaging system comprising an imaging gantry with an imaging axis extending through a bore of the imaging gantry, a support column that supports the imaging gantry on one side of the gantry in a cantilevered manner, and a base that supports the imaging gantry and the support column. The imaging system including a first drive mechanism that translates the gantry in a vertical direction relative to the support column and the base, a second drive mechanism that rotates the gantry with respect to the support column between a first orientation where the imaging axis of the imaging gantry extends in a vertical direction parallel to the support column and a second orientation where the imaging axis of the gantry extends in a horizontal direction parallel with the base, and a third drive mechanism that translates the support column and the gantry in a horizontal direction along the base.

A system and method for scanning a pig (or other food animal) to determine body composition and quality data in real time while the pig (or food animal) is suspended in mid-air by a lift apron in electronic communication with an ultrasound console and computer processor and configured to collect and process “target images” from the pig (or food animal) when a thumb switch activates the processor. The ultrasound probe is vertically displaced from and vertically adjustable relative to the framework so that the ultrasound probe is selectively positioned in relative space. With reference to target images, a processor calculates in real time a quantitative measurement indicative of backfat depth, muscle depth, and intramuscular fat for the pig (or food animal) being scanned.

A system for taking fluoroscopic images of large animals having a rotatable plate with a plurality of detectors disposed on the rotatable plate, wherein the detectors are arranged as spokes extending radially outwardly from a central rotational point on the rotatable plate with collimators disposed on the side edges of the spokes. A drive assembly rotates the plate about an axis extending through the central rotational point at a speed such that the duration of successive image frames corresponds to the time taken for each spoke of detectors to move to the position of an adjacent spoke of detectors.