Each conductor of a plurality of insulated conductors of a wiring harness extends between, and electrically connects, a corresponding terminal of a first electrical connector to either a corresponding terminal of an electrical connector jack of a plurality of electrical jacks located along the wiring harness, or to a corresponding terminal of a corresponding auscultatory sound-or-vibration sensor of the plurality of auscultatory sound-or-vibration sensors. The plurality of insulated conductors are organized in a plurality of distinct branches, each distinct branch originating either from the first electrical connector or from another portion of the wiring harness, and the locations of the plurality of distinct branches, in cooperation with the plurality of electrical jacks, if present, are implicitly suggestive of a corresponding location of the corresponding auscultatory sound-or-vibration sensor on a thorax of a test subject.

Each conductor of a plurality of insulated conductors of a wiring harness extends between, and electrically connects, a corresponding terminal of a first electrical connector to either a corresponding terminal of an electrical connector jack of a plurality of electrical jacks located along the wiring harness, or to a corresponding terminal of a corresponding auscultatory sound-or-vibration sensor of the plurality of auscultatory sound-or-vibration sensors. The plurality of insulated conductors are organized in a plurality of distinct branches, each distinct branch originating either from the first electrical connector or from another portion of the wiring harness, and the locations of the plurality of distinct branches, in cooperation with the plurality of electrical jacks, if present, are implicitly suggestive of a corresponding location of the corresponding auscultatory sound-or-vibration sensor on a thorax of a test subject.

A stimulation system includes an energy source, an electronics unit with a controller, and an actuator that is coupled with the electronics unit and/or the energy source. The actuator emits electromagnetic waves for stimulation of genetically manipulated tissue. The electronics unit is disposed in a housing. The stimulation system is configured for at least temporary implantation in a human or animal body. The controller controls the stimulation of tissue in the body by way of the electromagnetic waves emitted by the actuator. A selector of the stimulation system selects the area of the said tissue for stimulation. The selector includes a masking device for masking certain areas of the tissue, so that an intensity of the stimulation for the masked areas is reduced or equal to zero.

This disclosure relates generally to physiological monitoring, and more particularly to feature set optimization for classification of physiological signal. In one embodiment, a method for physiological monitoring includes identifying clean physiological signal training set from an input physiological signal based on a Dynamic Time Warping (DTW) of segments associated with the physiological signal. An optimal features set is extracted from a clean physiological signal training set based on a Maximum Consistency and Maximum Dominance (MCMD) property associated with the optimal feature set that strictly optimizes on the objective function, the conditional likelihood maximization over different selection criteria such that diverse properties of different selection parameters are captured and achieves Pareto-optimality. The input physiological signal is classified into normal signal components and abnormal signal components using the optimal features set.

This disclosure relates generally to physiological monitoring, and more particularly to feature set optimization for classification of physiological signal. In one embodiment, a method for physiological monitoring includes identifying clean physiological signal training set from an input physiological signal based on a Dynamic Time Warping (DTW) of segments associated with the physiological signal. An optimal features set is extracted from a clean physiological signal training set based on a Maximum Consistency and Maximum Dominance (MCMD) property associated with the optimal feature set that strictly optimizes on the objective function, the conditional likelihood maximization over different selection criteria such that diverse properties of different selection parameters are captured and achieves Pareto-optimality. The input physiological signal is classified into normal signal components and abnormal signal components using the optimal features set.

The invention is a method for processing a phonocardiographic signal characterising fetal breathing movement (FBM), wherein in initial start point (SP) determination (S100) in frequency filtering (S110), bandpass-filtered signals of frequency subbands by first and second bandpass filters are generated from the phonocardiographic signal, and first identified SP of an FBM episode is determined in a frequency subband in SP search (S120), in episode discovering (S130) further SP is searched applying the SP search (S120) in episode search time period, and if found at smaller distance from identified SP than a clustering threshold, it is merged with identified SP, if found at larger distance from identified SP than the clustering threshold, an SP closest to identified SP is identified as second identified SP.

The invention is, furthermore, a system for processing a phonocardiographic signal characterising FBM. (FIG. 4A)

A breathing sound measurement device includes a measurement section configured to be brought into contact with a skin of a front neck of a subject and measure breathing sound of the subject and a wearing section configured to have a first end connected to the measurement section and have elasticity to extend in a circular arc shape along an outer circumference of the subject's neck. The wearing section has a second end provided with a pressing portion configured to be pressed against a skin of a rear neck opposite a right front neck with respect to a midpoint between right and left halves of the subject's neck.

Apparatus and method are provided for synchronized multiple vital health measurements. In one novel aspect, an integrated wearable device with multiple sensors that can collect multiple vital health signals, digitize them, send them through wireless network to a receiver. In one embodiment, the wearable device has a plurality of different types of sensors including at least one or more acoustic-to-electric sensors collecting phonocardiogram (PCG) electrical signal and one or more electrocardiogram (ECG) sensors, a control module includes a synchronization circuitry that synchronizes measurements of the plurality of different types of sensors. In another novel aspect, a system performs a synchronized measurement using a plurality type of health-monitoring sensors, performs a correlation analysis of the plurality of measurement results using selected one or more analytical rules, and obtains a set of parameters with recognized medical values and generating one or more medical health records based on the correlation analysis.

A leadless implantable medical device (IMD) and method of using same are provided. The IMD comprises: a housing, a fixation element, electrodes configured to sense electrical cardiac activity (CA) signals over a period of time, an HS sensor configured to sense HS signals over the period of time, memory to store specific executable instructions, and one or more processors. The one or more processors and method: identify a characteristic of interest (COI) of a heartbeat from the CA signals, calculate a center of mass (COM) for at least one HS based on the HS signals to obtain a corresponding at least one HS COM, and calculate at least one of a therapy-related (TR) delay or a sensing-related (SR) blanking interval (BI) based on the at least one HS COM.

A sound detection system includes a plurality of microphones each configured to detect a sound inside a living body and output a sound signal generated based on the detected sound; and an information processing device that includes an acquisition unit configured to acquire the sound signal from each of the plurality of microphones, a control unit, and an output unit, the control unit specifies a first position that is a position of a prescribed living body site based on the sound signals acquired by the acquisition unit, estimates a second position that is in a prescribed relative positional relation with the first position, and controls directivities of the plurality of microphones to increase a sensitivity with respect to the second position, and the output unit outputs information generated based on the sound signals acquired by the acquisition unit in which the directivities of the plurality of microphones are controlled.