An ultrasound device captures skeleton density information. This ultrasound device includes at least two transmitters 100, 102 having a distance of L1 between them for transmitting ultrasound signals into the skeleton, at least two receivers 104 having a distance of L2 between them for receiving ultrasound signals from the skeleton, as the calibrated known distance L is at least one of distances L1 and L2. The ultrasound device also includes a processing unit 101 for calculating a ultrasound velocity in the skeleton for forming skeleton density information on the basis of the ultrasound signals received by the receivers 104, 106 by dividing known distance by an average of a travel time difference for a ultrasound signal between the receivers 104, 106 receiving the ultrasound signal from the first transmitter 100 and the second transmitter 102.

An ultrasound diagnostic apparatus includes an ultrasound image acquirer, an evaluation target determiner, a disease progression score calculator, a selector, and a display controller. The ultrasound image acquirer acquires ultrasound image signals of a plurality of frames. The evaluation target determiner analyzes the ultrasound image signal of each frame and determines the frame to be an evaluation target frame when the ultrasound image signal includes a target image section depicting a joint. The disease progression score calculator calculates, for each evaluation target frame, a disease progression score quantifying disease activity using an ultrasound image signal of the target image section included in the ultrasound image signal of the evaluation target frame. The selector selects at least one disease progression score in accordance with a predetermined numerical process. The display controller controls the display to display the selected disease progression score and an ultrasound image of a corresponding frame.

A system and computer-implemented method for analysing or monitoring a subject, the method comprising: identifying one or more objects of interest that have been segmented from a first image comprising any of a baseline scan, a follow-up scan or a reference image of the subject; identifying predefined landmarks of the objects; determining reference morphometries pertaining to the objects by performing morphometrics on the objects by reference to the landmarks; selecting one or more regions of interest (ROIs) from the objects according to the reference morphometries, comprising identifying respective locations of the ROIs relative to the reference morphometries; performing a first analysis of the one or more ROIs; performing at least one corresponding second analysis of the one or more ROIs in respectively at least one second image comprising any other of a baseline scan, a follow-up scan or a reference image; and generating a comparison of one or more results of the first analysis and one or more corresponding results of the second analysis.

An external ultrasound generating treating device (12) to induce spinal cord and/or spinal nerve treatment comprises at least two sub-arrays of ultrasound generating treatment transducers, a left sub-array (20iL) being located on a left lateral side and a right sub-array (20iR) being located on a right lateral side of the central longitudinal axis (Ai). The device comprises a support structure (32) having at least one module (34i) comprising a left lateral section (34iL) and a right lateral section (34iR). The support structure (32) maintains, in use of the device, a constant distance and a constant relative angular orientation around the central longitudinal axis (Ai) between the first left and first right treatment transducers or set of treatment transducers (20iL, 20iR). Also disclosed is an apparatus including the external ultrasound generating treating device (12) and methods of its use.

Methods and apparatus for treating a patient. The method includes acquiring a plurality of radio frequency (RF) signals with an ultrasound transducer, each RF signal representing one or more return echoes from a scan line of a pulse-mode echo ultrasound scan. A position of the ultrasound transducer corresponding to each of the acquired RF signals is determined, and a plurality of contour lines generated from the plurality of RF signals. The method estimates a 3-D shape and position of an anatomical feature, such as a joint of patient based on the generated contour lines and corresponding ultrasound transducer positions. An apparatus, or computer includes a processor and a memory with instructions that, when executed by the processor, perform the aforementioned method.

An ultrasound diagnostic device including an ultrasound image acquirer that acquires a plurality of ultrasound image signal frames; an angle information acquirer that acquires angle information of an ultrasound probe when each frame is being acquired; an evaluation determiner that analyzes the frames to determine whether an object image portion is included; a disease score calculator that calculates a disease score that quantitatively indicates a degree of disease from a signal of the object image portion; and a display controller that makes the diagnostic image be displayed. A diagnostic image includes an ultrasound image of a frame selected from the frames, a disease activity information indicator that indicates a degree of disease, and an angle information image portion that indicates angle information.

Systems and process are provided for a tool to create a registration matrix for a bone in three dimensional workspaces relative to a system using the absence of an ultrasonic reflection from an ultrasonic sensor attached to a tracking system to build the registration matrix model. The system has hardware and software that creates an absence of ultrasonic reflection, and utilizes the information to identify the location and orientation of a set of conic volumes in order to build an estimate of the position and orientation of the bone relative to the base system, and to use the position and orientation changes to update the registration and to detect bone motion. Embodiments of invention provide a process of registering part or all of a bone without directly touching the bone using ultrasound, and as a result support a non-invasive or less-invasive approach to bone registration and bone motion detection for a system.

A method for making a customized orthopedic surgical instrument for use in repairing a joint of a patient includes: obtaining image data associated with at least a portion of a bone corresponding to the joint of the patient; generating instructions to form a patient-specific orthopedic surgical instrument based at least in part on the image data; and forming the patient-specific orthopedic surgical instrument based on the instructions. The patient-specific orthopedic surgical instrument includes a resin composition, the resin composition including from about 50 wt % to about 90 wt % of a base thermoplastic and from about 10 wt % to about 50 wt % of a filler material. The base thermoplastic includes polyetherimide, polycarbonate, modified polyphenylene ether, polyamide, copolymers of these thermoplastics, and combinations thereof. The orthopedic surgical instrument includes at least one surface portion having a shape that substantially conforms to a corresponding surface portion of the bone.

A thickness measuring device using ultrasonic waves is provided. A cortical bone thickness measuring device includes a plurality of oscillators, a reception waveform storage, an echo waveform synthesizing module, an inner-surface focusing waveform acquiring module, and a thickness calculating module. The plurality of oscillators are arrayed and each of the oscillators is transmittable and receivable of an ultrasonic wave. The echo waveform synthesizing module obtains an echo waveform corresponding to the ultrasonic beams by synthesizing reception waveforms of the respective oscillators stored in the reception waveform storage in advance, while scanning a focusing position of the ultrasonic beams. Concerning the obtained echo waveform, when it is determined that the beams suitably focus on an inner surface of a cortical bone as a result of an evaluation by the inner-surface focusing waveform acquiring module, the thickness calculating module calculates the thickness of the cortical bone based on the echo waveform.

A device for intraoperative, image-controlled navigation during surgical procedures in the spinal and/or adjacent thorax, pelvis or head regions, includes multiple non-x-ray detection devices to be distributed about at least one object to be operated on, and to intraoperatively capture real time image and position data, respectively including information relating to the outer contour of at least one subregion of the object, and to the subregion position relative to the respective detection device. Also, a position determining device for determining respective detection device position relative to a stationary reference system, and a data processing device operatively connected with the detection devices and the position determining device are designed to create, based on the respective detection device image and position data and the position determining device position data, a virtual real-time image, referenced with respect to the reference system, of the object, and displayed on an image display device.