An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a processor configured to obtain a computerized model of a plurality of vascular segments of a patient and create an unstenosed computerized model from the computerized model by virtually enlarging at least some locations of the vascular segments of the computerized model. The processor also determines vascular state scoring tool (“VSST”) scores based on characteristics of vascular locations along the vascular segments. The processor further determines a severity of stenosis for the vascular locations based on comparisons of first blood flow parameter values at the vascular locations in the computerized model to corresponding second blood flow parameter values at the same vascular locations in the unstenosed computerized model. A user interface of the device displays the severity of stenosis in conjunction with the VSST scores for the vascular locations.

An apparatus for assessing the severity of stenosis in a blood vessel includes an elongate body including a distal portion and a centering assembly. The centering assembly is actuatable to selectively center the elongate body in the vessel. A pressure sensor is disposed adjacent the centering assembly and is configured to detect fluid pressure in the vessel. A processing system receives the measured pressure from the pressure sensor, receives data representing the cross-sectional area of the vessel, receives data representing the size of the distal portion, calculates a offset correlation based on the size of the distal portion and based on the size of the vessel, and calculates a fractional flow reserve (FFR) for the vessel as an index of stenosis severity taking into account the offset correlation and the measured fluid pressure from the pressure sensor.

An ultrasound diagnostic apparatus (1), which performs a compression test with respect to at least two points of a popliteal vein and a common femoral vein of a subject, includes an ultrasound probe (15), an image acquisition unit (8) that acquires an ultrasound image by transmitting an ultrasound beam toward the subject from the ultrasound probe (15), a vein detection unit (9) that detects the popliteal vein included in the ultrasound image, and an operation guiding unit (10) that guides a user, in a case where the compression test of the popliteal vein is performed, to operate the ultrasound probe such that the ultrasound probe (15) is positioned at a position in which only one popliteal vein is included in the ultrasound image based on the number of the popliteal veins detected by the vein detection unit (9).

Systems and methods for multi-level vascular imaging for construction and display of vasculature from large to small vessels and micro-vessels using a combination of varying resolution contrast enhanced ultrasound flow imaging modalities are disclosed. While one or more resolution flow imaging modes may be employed for imaging large to small vessels of a vascular tree within a large region of interest, a high resolution mode, such as super resolution imaging, constructed for delineation of the microvascular morphology and directional microcirculation is provided within one or more small ROIs placed in selected locations within the larger ROI.

Various approaches for computationally characterizing tissue in an anatomic target region include generating multiple sonications to transient acoustic reflectors at or proximate to the target region; measuring reflection signals of the sonications off the transient acoustic reflectors; based on the measurements, identifying the reflection signals originating from single transient acoustic reflectors; and based at least in part on the identified reflection signals, generating a digital map including a tissue characteristic.

An implantable sensor system using one or more sensor implants comprised of micro-electrical mechanical system (MEMS) sensors for the accurate and continuous measurement of physiological hemodynamic signals such as diastolic and systolic blood pressure. Sensor implants are configured to be subcutaneously injected to a placement site adjacent a blood vessel. In some embodiments, sensors comprise micromachined ultrasonic transducers.

Methods include capturing intravascular ultrasound images. A drive motor is used to actively drive an ultrasound transducer at a set rotation speed. A temporary sensing window is created in which the ultrasound transducer is driven with a fixed drive signal. A plurality of signals from are received the ultrasound transducer during the temporary sensing window.

An ultrasound diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to speculate saturation of reflected-wave signals observed before a phased addition process performed by using the reflected-wave signals, in accordance with an intensity of reflected-wave data generated through the phased addition process, the reflected-wave signals being generated by transmitting an ultrasound wave with respect to mutually the same scanning line, and the processing circuitry is configured to output a result of the speculation. The processing circuitry is configured to cause a display to display data based on the result of the speculation.

An image processing device is an image processing device configured to cause a display to display, as a three-dimensional image, three-dimensional data representing a biological tissue having a longitudinal lumen. The image processing device includes: a control unit configured to calculate centroid positions of a plurality of cross sections in a lateral direction of the lumen of the biological tissue by using the three-dimensional data, set a pair of planes intersecting at a single line passing through the calculated centroid positions as cutting planes, and form, in the three-dimensional data, an opening exposing the lumen of the biological tissue from a region interposed between the cutting planes in the three-dimensional image.

Disclosed is an intraluminal ultrasound imaging system, including a processor circuit in communication with an intraluminal ultrasound imaging catheter, and configured to receive a plurality of intraluminal ultrasound images obtained by the imaging catheter while the imaging catheter is moved through a body lumen of a patient. The processor circuit is further configured to determine a longitudinal translation speed of the imaging catheter based on the plurality of images and a known time interval between images, and display a speed indicator based on the longitudinal translation speed.