The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.

The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.

A device is provided for ultrasound-based reflection and transmission tomography. A plurality of ultrasonic transducers are held around an imaging volume to be filled with an ultrasonic coupling medium, the transducer holder having an opening for inserting, into the imaging volume, at least one part of a body to be imaged. During imaging, the body to be imaged is supported, where a support-member-opening allows access to the transducer holder by at least one part of the body. A diaphragm is arranged across the support-member-opening such that a center of a diaphragm-opening is placed substantially at a predetermined position. The ultrasonic coupling medium flows out of the imaging volume when at least one part of the body to be imaged is inserted into the imaging volume filled with the ultrasonic coupling medium and/or during imaging.

A device is provided for ultrasound-based reflection and transmission tomography. A plurality of ultrasonic transducers are held around an imaging volume to be filled with an ultrasonic coupling medium, the transducer holder having an opening for inserting, into the imaging volume, at least one part of a body to be imaged. During imaging, the body to be imaged is supported, where a support-member-opening allows access to the transducer holder by at least one part of the body. A diaphragm is arranged across the support-member-opening such that a center of a diaphragm-opening is placed substantially at a predetermined position. The ultrasonic coupling medium flows out of the imaging volume when at least one part of the body to be imaged is inserted into the imaging volume filled with the ultrasonic coupling medium and/or during imaging.

Systems, devices, and methods are disclosed for acquiring and providing information about orthopedic features of a body using acoustic energy. In some aspects, an acoustic orthopedic tracking system includes portable acoustic transducers to obtain orthopedic position information for feeding the information to an orthopedic surgical system for surgical operations.

An ultrasound diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to generate an ultrasound image on the basis of a result of an ultrasound scan performed on a region including a part of a subject. The processing circuitry is configured to obtain a schematic image schematically indicating the part of the subject. The processing circuitry is configured to cause a display to display the schematic image and either the ultrasound image or an image based on the ultrasound image, in such a manner that the orientation of the subject included in either the ultrasound image or the image based on the ultrasound image and the orientation of the subject indicated in the schematic image are close to each other, on the basis of an analysis result from an analysis performed on either the ultrasound image or the image based on the ultrasound image.

The present invention provides improved methods and systems for generating enhanced images of a volume of tissue. In an aspect, the method comprises receiving from a transducer, a plurality of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; generating from the acoustic signals, a first reflection rendering that characterizes sound reflection, the first reflection rendering comprising a first distribution of reflection values across a region of the volume of tissue; generating from the acoustic signals, a sound speed rendering that characterizes sound speed, the sound speed rendering comprising a distribution of sound speed values across the region; generating from the sound speed rendering, a second reflection rendering that characterizes sound reflection, the second reflection rendering comprising a second distribution of reflection values across the region; and rendering one or more combined images, based on the first reflection rendering and the second reflection rendering.

The present invention provides improved methods and systems for generating enhanced images of a volume of tissue. In an aspect, the method comprises receiving from a transducer, a plurality of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; generating from the acoustic signals, a first reflection rendering that characterizes sound reflection, the first reflection rendering comprising a first distribution of reflection values across a region of the volume of tissue; generating from the acoustic signals, a sound speed rendering that characterizes sound speed, the sound speed rendering comprising a distribution of sound speed values across the region; generating from the sound speed rendering, a second reflection rendering that characterizes sound reflection, the second reflection rendering comprising a second distribution of reflection values across the region; and rendering one or more combined images, based on the first reflection rendering and the second reflection rendering.

A cervix probe is equipped with a tactile sensor array and an ultrasound transducer and configured for simultaneous acquisition of stress data and ultrasound strain data for the same sector of the cervix. Acquired and recorded stress and strain data are transmitted to a data processor for calculating cervix elasticity and cervix length, followed by calculating a probability of spontaneous preterm delivery using a clinically validated predictive model.

In an embodiment, a system and method are provided for determining position and orientation of an optical delivery unit relative to an acoustic receiving unit, in the field of opto-acoustic imaging, wherein the optical delivery unit comprises a first fiducial marker site configured to emit acoustic responses and a second fiducial marker site configured to emit acoustic responses. A plurality of acoustic signals from a volume of a subject are sampled and recorded, each of the plurality of acoustic signals being collected at a different data collection position relative to a coordinate reference frame. The system is configured to identify in each of the plurality of acoustic signals a response of a first fiducial marker and a response of a second fiducial marker. Each identified response indicates a separation between a fiducial marker site and a data collection position of an acoustic signal. The system determines the position and orientation of the optical delivery unit in the coordinate reference frame by using the identified responses of the first fiducial marker and the identified responses of the second fiducial marker.