This disclosure relates to a composition (e.g., a cleaning and/or stripping composition) containing (a) 0.5-25 percent by weight an alkaline compound; (b) 1-25 percent by weight an alcohol amine compound; (c) 0.1-20 percent by weight a hydroxylammonium compound; (d) 5-95 percent by weight an organic solvent; (e) 0.1-5 percent by weight a corrosion inhibitor compound; and (f) 2-25 percent by weight water.

Among other things, a method for performing multiple enzyme reactions in a single tube is provided. In some embodiments, the method may comprise producing a reaction mix comprising a thermolabile UDG, an AP lyase and DNA fragments that comprise one or more uracil residues, incubating the reaction mix at a relatively low temperature to cleave fragments at the one or more uracil residues, raising the temperature of the reaction mix to a relatively high temperature to inactivate the thermolabile UDG; and deaminating the fragments, thereby converting any cytosine in the fragments of DNA to uracil.

Among other things, a method for performing multiple enzyme reactions in a single tube is provided. In some embodiments, the method may comprise producing a reaction mix comprising a thermolabile UDG, an AP lyase and DNA fragments that comprise one or more uracil residues, incubating the reaction mix at a relatively low temperature to cleave fragments at the one or more uracil residues, raising the temperature of the reaction mix to a relatively high temperature to inactivate the thermolabile UDG; and deaminating the fragments, thereby converting any cytosine in the fragments of DNA to uracil.

The present invention is a cleaning composition including a binder, a gas generator, an acid, and at least about 0.1% water. The cleaning article has an aged Shore A hardness of at least about 10, an aged Shore D hardness of up to about 100, and a dissolution time of between about 1 minute and about 60 minutes.

The present invention relates to co-granules comprising an enzyme and a bleach catalyst and to their use in bleach-containing granular automatic dishwash (ADW) detergents.

A lavatory cleansing block including: an alkane sulfonate; a carboxymethylcellulose; a hydrophobe; and optionally a dye, wherein the alkane sulfonate is present in an amount of 15 to 40% by weight of the total block, the weight ratio of alkane sulfonate to carboxymethylcellulose is 3:1 to 8:1 and the total weight of the block is less than 25 g.

The present invention relates to a solid free flowing particulate laundry detergent composition including: (a) anionic detersive surfactant; (b) wherein the composition is essentially free of zeolite builder; (c) wherein the composition is essentially free of phosphate builder; (d) wherein the composition is essentially free of sodium carbonate; (e) wherein the composition is essentially free of sodium silicate; (f) from about 4 wt % to about 20 wt % organic acid; and (g) phthalocyanine photobleach, wherein the composition at 1 wt % dilution in deionized water at 20 C., has an equilibrium pH in the range of from about 6.5 to about 9.0, wherein the composition includes from about 30 wt % to about 90 wt % base detergent particle, wherein the base detergent particle including (by weight of the base detergent particle): (a) from about 4 wt % to about 35 wt % anionic detersive surfactant; (b) from about 1 wt % to about 8 wt % zeolite builder; (c) wherein the particle is essentially free of phosphate builder; (d) wherein the particle is essentially free of sodium carbonate; (e) wherein the particle is essentially free of sodium silicate; (f) from about 1 wt % to about 10 wt % organic acid; and

The present invention relates to a solid free flowing particulate laundry detergent composition including: (a) anionic detersive surfactant; (b) wherein the composition is essentially free of zeolite builder; (c) wherein the composition is essentially free of phosphate builder; (d) wherein the composition is essentially free of sodium carbonate; (e) wherein the composition is essentially free of sodium silicate; (f) from about 4 wt % to about 20 wt % organic acid, (g) a variant of the wild-type amylase from Bacillus sp. which has at least 90% identity for amino acid sequence SEQ ID NO:5, and which includes one or more mutations at positions N195, G477, G304, W140, W189, D134, V206, Y243, E260, F262, W284, W347, W439, W469 and/or G476, wherein the composition at 1 wt % dilution in deionized water at 20 C., has an equilibrium pH in the range of from about 6.5 to about 9.0.

The present invention relates to a solid free flowing particulate laundry detergent composition including: (a) anionic detersive surfactant; (b) wherein the composition is essentially free of zeolite builder; (c) wherein the composition is essentially free of phosphate builder; (d) wherein the composition is essentially free of sodium carbonate; (e) wherein the composition is essentially free of sodium silicate; (f) from about 4 wt % to about 20 wt % organic acid; and (g) variant of the wild-type amylase from Bacillus sp. which has at least 90% identity for amino acid sequence SEQ ID NO:6, and which comprises one or more mutations at positions 9, 26, 30, 33, 82, 37, 106, 118, 128, 133, 149, 150, 160, 178, 182, 186, 193, 195, 202, 214, 231, 256, 257, 258, 269, 270, 272, 283, 295, 296, 298, 299, 303, 304, 305, 311, 314, 315, 318, 319, 320, 323, 339, 345, 361, 378, 383, 419, 421, 437, 441, 444, 445, 446, 447, 450, 458, 461, 471, 482 and/or 484, wherein the composition at 1 wt % dilution in deionized water at 20 C., has an equilibrium pH in the range of from about 6.5 to about 9.0.

The present invention relates to a solid free flowing particulate laundry detergent composition including: (a) anionic detersive surfactant; (b) wherein the composition is essentially free of zeolite builder; (c) wherein the composition is essentially free of phosphate builder; (d) wherein the composition is essentially free of sodium carbonate; (e) wherein the composition is essentially free of sodium silicate; (f) from about 4 wt % to about 20 wt % organic acid; and (g) hueing agent having the following structure:

##STR00001##

wherein:
R1 and R2 are independently selected from the group consisting of: H; alkyl; alkoxy; alkyleneoxy; alkyl capped alkyleneoxy; urea; and amido;
R3 is a substituted aryl group;
X is a substituted group comprising sulfonamide moiety, and wherein the substituent group comprises at least one alkyleneoxy chain that comprises an average molar distribution of at least four alkyleneoxy moieties, wherein the composition at 1 wt % dilution in deionized water at 20 C., has an equilibrium pH in the range of from about 6.5 to about 9.0, wherein the composition includes from about 30 wt % to about 90 wt % base detergent particle, wherein the base detergent particle including (by weight of the base detergent particle): (a) from about 4 wt % to about 35 wt % anionic detersive surfactant; (b) from about 1 wt % to about 8 wt % zeolite builder; (c) wherein the particle is essentially free of phosphate builder; (d) wherein the particle is essentially free of sodium carbonate; (e) wherein the particle is essentially free of sodium silicate; (f) from about 1 wt % to about 10 wt % organic acid.