A mixed reality (MR) visualization system includes an MR device comprising a holographic display configured to display a holographic image to an operator, a hand-held ultrasound imaging device configured to obtain a real-time ultrasound image of a subject's anatomy, and a computing device communicatively coupled to the MR device and the hand-held ultrasound imaging device. The computing device includes a non-volatile memory and a processor. The computing device is configured to receive the real-time ultrasound image, determine a real-time 3D position and orientation of the hand-held ultrasound imaging device, generate a modified real-time ultrasound image by modifying the real-time ultrasound image to correspond to the real-time 3D position and orientation of the hand-held ultrasound imaging device, and transmit the modified real-time ultrasound image to the MR device for display as the holographic image positioned at a predetermined location relative to the hand-held ultrasound imaging device.

Systems and methods for deep tissue visualization using ultrasound and stereo imaging are provided. Various aspects of the present disclosure provide intraoperative identification of sub-tissue surface critical structures (e.g., identification of ureters, nerves, and/or vessels). For example, various surgical visualization systems disclosed herein can enable the visualization of one or more portions of critical structures below the surface of the tissue in an anatomical field in real-time. Such surgical visualization systems can augment the clinician's endoscopic view of an anatomical field with a virtual, real-time depiction of the critical structure as a visible image overlay on the surface of visible tissue in the field of view of the clinician.

Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system includes one or more external optical emitters and a measurement apparatus configured to be placed within a vascular pathway. The measurement apparatus may include a sensor array comprising sensors of two or more types. The sensors may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, and transmit and receive ultrasound signals. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

An ultrasound imaging system with an inertial tracking sensor (20) rigidly fixed to an ultrasound probe (10). In a first embodiment, a real-time pose estimation unit (32) enhances image based tracking using the inertial data stream to calculate out-of-plane angles of rotation and determine an out-of-plane translation by iteratively selecting planes with the estimated out-of-plane rotations with varying out-of-plane offset, computing the differences between sub-plane distances computed by speckle analysis and the selected plane minimizing for the root mean square of the differences for all selected planes. In another embodiment, the real-time pose estimation unit enhances inertial tracking using the ultrasound image data stream to estimate an in-plane rotation angle; and substituting the in-plane rotation angle for an angle of rotation estimated using the inertial data stream.

A photoacoustic and ultrasonic endoscope includes an optical fiber, a light diffuser configured to radially diffuse a laser beam transmitted through the optical fiber, and an array transducer having a cylindrical shape and surrounding the light diffuser, the array transducer being configured to transmit the diffused laser beam therethrough and to generate an ultrasonic wave or detect an ultrasonic wave generated by an object to be examined.

A probe includes a working channel, at least one optical element provided in the working channel and configured to acquire a spectral image of surface information of an object, and an ultrasonic transducer arranged in the working channel and configured to acquire an ultrasonic image of depth information of the target and move with respect to the at least one optical element.

A system (10) is for performing ECG measurements and comprises a probe (12) with an integrated one or more ECG electrodes (22) and an ultrasound sensing means (18), such as a transducer arrangement. The probe thus provides a mobile ECG electrode which can be sequentially moved between a set of different locations on the body for acquiring ECG measurements from different angles relative to the heart (i.e. different ‘leads’). Positioning of the probe in each required location is guided by a position guidance function which uses ultrasound data acquired by the ultrasound sensing means to locate the probe (with reference to an ultrasound body atlas (28) or map), and uses a stored set of reference body locations to guide a user with guidance information as to how to move the probe to arrive at a next target electrode location. In examples, the user may be guided through a sequence of electrode locations, with ECG data acquired at each one, thereby sequentially building up a set of standard ECG lead measurements.

A blood pressure detection method is provided. The method comprising: obtaining wrist circumference data, wrist fat thickness data, and blood pressure data and correcting the blood pressure data based on the wrist circumference data and the wrist fat thickness data.

An electronic device is provided. The electronic device includes a photoplethysmography (PPG) sensor comprising a light source and a light sensor, an ultrasonic device, at least one processor operatively connected to the PPG sensor and the ultrasonic device, and a memory operatively connected with the at least one processor. The memory may store one or more instructions which, when executed, cause the at least one processor to acquire a PPG signal based on light detected by the light sensor, and control the operation of the ultrasonic device on the basis of an index value indicating the quality of the PPG signal.

A breast composition information acquisition unit acquires information related to a breast composition of a subject obtained by a mammography examination. An analysis determination unit determines whether or not to perform analysis on a glandular tissue component (GTC) region including mammary ducts, lobules, and peripheral stromata in a mammary gland region based on the information related to the breast composition of the subject. A GTC region analysis unit performs analysis on the GTC region based on an ultrasound image obtained by imaging a breast of the subject in a case where it is determined to perform analysis.