The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling.

This method, for determining the local intensity (I.sub.0) of an acoustic field propagating in a target region of a soft solid, at a position located within said target region, includes at least the following steps: determining (102) a value of an ultrasound attenuation coefficient (α) of the soft body in the target region; determining (104) a value of the shear modulus (μ) of the soft body in the target region; determining (106) a value of the speed of sound (c) in the target region of the soft body; and building (110), with the values determined in steps a), b) and c), a viscoelastic model (M) of a steady-state displacement induced by an acoustic field having a time invariant shape or a viscoelastic model of a difference between two steady-state displacements induced by an acoustic field having a time invariant shape. Moreover, this method also includes the following steps: applying (112) to the target region the acoustic field emitted by an ultrasound source, for a duration such that the acoustic field induces a steady-state localized deformation (Formula (I)) of the soft body in the target region; measuring (114) at least one steady state displacement induced by the acoustic field at a given position in the target region; and computing (116) the amplitude of the intensity of the acoustic field at said given position by inverting the viscoelastic model (M) at said given position, for the displacement(s) measured at step f).

A shear wave elastography method for imaging an observation field in an anisotropic medium, including an initial ultrasonic acquisition step during which initial physical parameters are acquired in at least one region of interest; a spatial characterization step during which a set of spatial characteristics of the anisotropic medium is determined on the basis of the initial physical parameter; an excitation substep during which an shear wave is generated inside the anisotropic medium on the basis of the set of spatial characteristics; and an observation substep during which the propagation of the shear wave is observed simultaneously at a multitude of points in the observation field.

Apparatuses, systems, and methods of monitoring lesion formation using one-dimensional echograms are disclosed. In certain aspects, lesion formation progress is monitored using the intensity of reflectors in successive echograms during ablation. In another aspect, lesion formation progress is monitored based upon actual or apparent movement of acoustic reflectors before and after ablation. In still another aspect, the presence or absence of resonant microbubbles known to populate forming lesions are used to provide feedback on lesion formation. A lesion analysis processor can be programmed to determine lesion formation progress using any of the foregoing approaches, either alone or in various combinations.

Various methods and systems are provided for ultrasound imaging. In one embodiment, a method comprises acquiring, with an ultrasound transducer of a scanning apparatus during an ultrasound scan of a patient, an ultrasound image, detecting, with an artificial intelligence model, a region of interest within the ultrasound image including a possible tumor, acquiring, with the ultrasound transducer, an elastic image of tissue within the region of interest, and displaying, with a display device, the elastic image. In this way, shear wave elastography may be automatically targeted to a region of interest, thereby reducing the processing load for the analysis and enabling a higher elasticity imaging frame rate for three-dimensional ultrasound imaging.

Systems and methods are disclosed that facilitate obtaining two dimensional (2D) ultrasound images, using two or more ultrasound imaging modes or modalities, to generate 2D multi-parametric ultrasound (mpUS) images and/or to generate a three-dimensional (3D) mpUS image. The different ultrasound imaging modes acquire images in a common frame of reference during a single procedure to facilitate their registration. The mpUS images (i.e., 2D or 3D) may be used for enhanced and/or automated detection of one or more suspicious regions. After identifying one or more suspicious regions, the mpUS images may be utilized with a real-time image to guide biopsy or therapy the region(s). All these processes may be performed in a single medical procedure.

Systems and methods are disclosed that facilitate obtaining two dimensional (2D) ultrasound images, using two or more ultrasound imaging modes or modalities, to generate 2D multi-parametric ultrasound (mpUS) images and/or to generate a three-dimensional (3D) mpUS image. The different ultrasound imaging modes acquire images in a common frame of reference during a single procedure to facilitate their registration. The mpUS images (i.e., 2D or 3D) may be used for enhanced and/or automated detection of one or more suspicious regions. After identifying one or more suspicious regions, the mpUS images may be utilized with a real-time image to guide biopsy or therapy the region(s). All these processes may be performed in a single medical procedure.

For parametric ultrasound imaging with an ultrasound scanner, the values for multiple parameters are determined for tissue of a patient using ultrasound. The determination may be in response to a single activation, avoiding the user having to reconfigure and activate separately for each parameter. To assist in diagnosis, one or more indicators of quality of the measurements of the parameters are calculated and displayed to the user. To further assist in diagnosis, the measurement values for the patient are displayed relative to published or population values.

Image analysis method for quantitative assessment of a degree of coordination of uterine motion, comprising: obtaining a recording of a uterus; tracking, in the recording, at least two propagation waves of uterine motion in at least two different regions of the uterus and/or on at least two different times; and determining the degree of coordination of the uterine motion based on a similarity measure of at least two characteristics of the at least two propagation waves.

The present disclosure relates to an ultrasound elastography system and method. The system may include a transmitting/receiving unit which transmits ultrasound pulses to a target and receives ultrasound echoes from the target to obtain the ultrasound echo signals; an imaging unit which processes the ultrasound echo signals and displays the obtained image; and an analysis unit which detects a region of interest and a shell region selected by an operator in the image, calculate elasticity parameters in a reference region and the shell region respectively, and analyzes the elasticity parameters to obtain an analysis result.