A method for using saliva to measure at least one substance or physiological parameter of a human or animal subject may involve inserting a first end of a sensor into a handheld saliva testing device. The method may also involve receiving saliva from the subject on a second end of the sensor, moving the saliva from the second end of the sensor to the first end, and processing the saliva with the handheld saliva testing device to provide initial saliva data related to the at least one substance or physiological parameter of the subject. In some embodiments, the sensor remains inserted in the handheld device while the subject deposits saliva on the opposite, free end of the sensor.

Disclosed herein are a group of gastric cancer VOC markers in saliva and an application thereof in the preparation of a diagnostic reagent of gastric cancer. The markers are a combination of compounds selected from the group consisting of acetaldehyde, 2-methylbutyraldehyde, isopropanol, hexanal, n-butanol, cineole, nonanal, menthone, 2-ethylhexanol, menthol, anethole and dodecanol. The diagnostic reagent is used for detecting the contents of the marker in a saliva sample of a subject to perform the diagnosis of gastric cancer.

Provided herein are methods and a device for collecting biological samples. In particular, the present disclosure relates to a device designed to specifically capture samples within the target areas of a patient for specific cell collection for particular diagnosis.

The present invention relates to a body fluid observation device which enables observation of a user's body fluid. A body fluid observation device according to an example of the present invention comprises: a chamber which has a length in a first horizontal direction and in which a body fluid of a user is stably placed; and a body into which the chamber is inserted for observation of the body fluid. The body comprises: a case including a chamber insertion hole which is formed through the front surface of the body and into which the chamber is inserted, a guide partition wall extending from the chamber insertion hole in the first horizontal direction to guide the chamber, and an observation hole provided through the bottom surface of the body to allow observation of the body fluid; a light source part which is positioned above the chamber in the case and emits light; and an operation part electrically connected to the light source part to operate the light source part, wherein, as the chamber is inserted into the chamber insertion hole, the operation part can form an electrically closed loop for operating the light source part.

A fluid collection system comprises a sealed reagent container that fits inside a sample container and is unsealed by disengaging a seal comprised in a sample container. The sealed reagent container contains a reagent, such as a nucleic acid preservative. The reagent container also includes a sleeve disposed opposite the sealed opening. The sleeve includes a distal opening for receiving a sample and a proximal opening disposed in the sample container for guiding a sample from the distal opening and through the proximal opening into the sample container. Disengaging the seal releases the reagent into the sample container with the sample, where they mix.

A roll sheet type sample collection kit according to an embodiment includes a fixing bar provided as a member having a given length, a collection sheet rolledly fixed to one end of the fixing bar to attachedly collect the sample thereonto, a support bar adapted to allow the fixing bar and the collection sheet to protrude from one side thereof and to be grasped while the sample is being collected, and a cap detachably mounted to surround the fixing bar and the collection sheet protruding from the support bar. The roll sheet type sample collection kit performs a sample test in a gentle and accurate manner, and easily removes a portion where the sample is collected therefrom so as to perform the sample test, thereby enhancing quickness and conveniences in the sample test.

In one aspect, a sample collection device for collecting a biological sample is disclosed, which comprises a sample-receiving cup having a body that extends from a proximal opening to a distal opening, where the proximal opening is configured for receiving a biological sample. The sample collection device further includes a sensor comprising at least one sensing unit, where the sensor is sealingly connected to the distal opening of the sample-receiving cup such that the sensing unit is exposed to the distal opening. A reservoir for storing one or more sample-processing reagents is provided in the fluid-receiving cup such that the sensing unit is in fluid contact with the reagent(s) stored in the reservoir. A frangible membrane separates the reservoir from the proximal opening.

Methods and devices to capture and analyze aerosolized particles such as protein biomarkers and their truncated proteoforms characteristic of a disease, including a respiratory disease, in exhaled breath to enable rapid detection of diseases are disclosed. The disclosed methods and systems selectively capture aerosolized particles using a packed bed column. The captured particles are then eluted using one or more solvents and analyzed using devices including mass spectrometry.

The present invention relates to a method for determining an analyte using surface enhanced RAMAN spectroscopy and to a device which is suitable for this purpose.