Devices and methods for microbiome sampling and evaluation are disclosed. Devices including a capture substrate having first and second regions suitable for first and second analytic methods, respectively, are disclosed. Methods for collecting the microbiome sample with such devices are disclosed. Methods of evaluating the microbiome sample collected with such devices are disclosed. Kits including the devices for sampling and evaluating microbiome samples are also disclosed.

A method for measuring glucose and cortisol levels in earwax, wherein the measured levels of cortisol and glucose are interpreted as the average cortisol and glucose levels and a medical device that provides an effective, safe and hygienic self-extraction of earwax.

A sample collecting device for collecting samples of cellular material includes an outer tubular member, an inner tubular member and a swab having a tip. At least one guiding element supports and slidably arranges the swab in the inner tubular member such that there is a free space around the swabbing tip. A flexible valve is arranged at a distal end of the outer tubular member. In a storage configuration, the valve is closed and seals the distal end of the outer tubular member. In a sampling configuration, the valve is open such that the swab is slidable to extend through the distal end of the outer tubular member without contacting the valve. A swab kit for collecting and storing samples of cellular material from body cavities includes a sample collecting device and a sealable container adapted to receive and store at least a part of the sample collecting device.

The present invention provides a device that can move inside a biological conduit such as an intestinal tract for sampling the content therein, and a process thereof. While moving along the intestinal tract, the device can continuously collect the content in the intestinal tract. One or more convoy belts having an adsorbent layer are configured to continuously absorb and preserve the collected intestinal content. The belt loaded with the sample may be used to establish a chemical, biochemical and microbiological spectrum along the length of the intestinal tract.

Devices and methods for microbiome sampling and evaluation are disclosed. Devices including a capture substrate having first and second regions suitable for first and second analytic methods, respectively, are disclosed. Methods for collecting the microbiome sample with such devices are disclosed. Methods of evaluating the microbiome sample collected with such devices are disclosed. Kits including the devices for sampling and evaluating microbiome samples are also disclosed.

An apparatus for controlled perforation and aspiration of the inner ear.

An apparatus for controlled perforation and aspiration of the inner ear having a distal portion including a plurality of apices and a plurality of valleys therebetween defining a plurality of serrated blades.

The invention relates to a device for in vivo sampling of biological species, comprising: a tubular sheath extending between a proximal end of said sheath and a distal end of said sheath, said distal end of the sheath having a projecting part, a rod extending between a proximal end of said rod and a distal end of said rod, capable of sliding in the sheath between a retracted position in which the distal end of the rod is located inside the sheath and a deployed position in which the distal end of the rod extends beyond the distal end of the sheath,
said rod comprising a capturing support for capturing said biological species, made from a porous material, arranged in a distal region of the rod on a portion of the circumference of the rod such that the capturing support is located outside the sheath when the rod is in the deployed position of same.

Devices and methods for microbiome sampling and evaluation are disclosed. Devices including a capture substrate having first and second regions suitable for first and second analytic methods, respectively, are disclosed. Methods for collecting the microbiome sample with such devices are disclosed. Methods of evaluating the microbiome sample collected with such devices are disclosed. Kits including the devices for sampling and evaluating microbiome samples are also disclosed.

The invention relates to materials, methods and devices useful for sampling biological molecules, including biomarkers and/or metabolites. In particular, the invention relates to surface functionalised xerogels and surface functionalised poly(dimethyl) siloxane (PDMS), devices comprising those materials, and methods of using the materials and devices for sampling, analysing or detecting biological molecules.