A printed structure including a plurality of overlying layers of elongate polymeric filaments stacked on a surface of a substrate. The elongate polymeric filaments are stacked on each other along their lengths to form a liquid impermeable, self-supporting wall. The liquid impermeable self-supporting wall forms a wall angle of about 30° to about 90° with respect to a plane of the surface of the substrate.

The present invention relates to a sample collection and testing device for analyzing and testing an analyte in a liquid sample. The sample collection device includes a collection inner cavity and a collection outer cavity. The collection inner cavity is disposed inside the collection outer cavity. The collection inner cavity communicates with the collection outer cavity via through holes at a bottom portion of the collection inner cavity. The collection inner cavity is movable between a first position and a second position relative to the collection outer cavity. When the collection inner cavity is at the first position, the liquid sample is collected into the collection outer cavity. When the collection inner cavity is at the second position, the liquid sample is discharged out of the collection outer cavity.

Embodiments of the disclosed invention provide wearable devices that use a humidity sensor to measure sweat rate generated from an area of skin. A sensing chamber is continuously filled with a sweat sample, which forms a droplet and alters the humidity measured within the chamber. Once the sweat sample droplet expands to the edge of the chamber, the droplet contacts a wick and is drawn away, so the chamber can fill with a subsequent droplet. The device uses a droplet volume and the time required to reach a maximum humidity to calculate a sweat rate. A pump is used to draw old sweat sample out of the wick to allow extended device operation. Some embodiments also include capacitive sensors to perform back up measurements. Another set of embodiments includes alternatively shaped sensing chambers configured to reduce sample volumes or improve function. A method for determining sweat rate based on humidity sensor measurements is also included.

Systems, devices and methods are described herein for various embodiments of a sample analysis system that is worn by a user, the sample analysis system configured to collect a sample of bodily fluid, and measure and analyze the bodily fluid to determine a property of the bodily fluid and/or a health parameter (e.g., degree of hydration, electrolyte losses, perspiration rate, etc.) of the user.

A blood glucose measurement device and a blood glucose measurement system using the same are proposed, the device being non-invasive, measuring blood glucose with sweat rather than blood, having a sweat-inducing means that requires no drug in a sweat induction process, and including: a sweat-inducing part having two electrodes arranged to be spaced apart from each other and to which opposite polarities are respectively applied; a housing for fixing the sweat-inducing part allowing the two electrodes to be exposed on one surface of the housing; and a blood glucose sensor inserted into the housing and in contact with body fluids induced by the sweat-inducing part, whereby pain, infection, and scars do not occur, the drugs that may affect the normal sweat-inducing mechanism in the skin are not used, and all the collected sweat is used to measure the blood glucose level with high-accuracy.

A method for monitoring intoxication of a user, the method including: receiving a set of samples from a body region of a user; generating an intoxication metric based on the set of samples; and providing a notification to the user based on the intoxication metric. The method can additionally or alternatively include: modifying operation of the transdermal alcohol sensing device based on the intoxication metric; determining contextual data; maintaining a hydration level of the transdermal alcohol sensing device; and any other suitable processes. A system for monitoring intoxication of a user including a sensor and a housing. The system can additionally or alternatively include any or all of: an inlet, a fastener, an electronics subsystem, a user device, and/or any other suitable component.

Disclosed are apparatuses, methods, and method of manufacture of a microfluidic device for detecting biomolecules in sweat, and a biosensor patch for detecting biomolecules in sweat, in which the microfluidic device and a biosensor are combined, the device and the patch being capable of detecting various target molecules present in sweat by electrochemical signals and also detecting the concentration of a target molecule. The microfluidic device includes a fluidic passing layer including an inlet part, a sensing element in communication with the inlet part, a reagent storage part in communication with the sensing element part, and a disposer in communication with the sensing element, and a fluidic connection layer including a microfluidic tube arranged in a vertical direction to the inlet part, a sensing space provided between the sensing element and the biosensor, and a reagent storage space positioned below the reagent storage part, the fluidic connection layer being disposed below the fluidic passing layer.

Methods, systems, and devices are described herein for various embodiments of using a sample analysis system to analyze a sample of bodily fluid from a user to determine parameters associated with the user including states of hydration, dehydration, rehydration, electrolyte loss, wellness, recovery, and the like. In some embodiments, the methods disclosed can be implemented using a device worn by a user, and operatively coupled to a sample analysis system configured to collect a sample of bodily fluid, and measure and analyze the bodily fluid to determine a property of the bodily fluid and/or a physiological/wellness parameter (e.g., degree of hydration, electrolyte losses, perspiration rate, etc.) of the user.

A wearable device can include a sweat collection unit, and optionally, a sweat stimulation unit. The sweat collection unit includes at least one microfluidics channel to collect sweat from a user, a chamber to hold the sweat, and a loading chamber with sweat collection paper that attracts the sweat through the chamber. A chloride sensing unit located within the chamber includes a gold working electrode and a counter electrode that can determine if enough sweat is in the chamber and, if enough, the chloride concentration of the sweat can be determined based on electrochemical reactions in response to electrical signals applied through the electrodes. A controller of the device can notify a user to trigger the sweat stimulation unit if not enough sweat is in the chamber.

Systems and methods including a device having integrated sensor arrays constructed and configured to measure and analyze multiple biosignatures concurrently in real time and a mobile application to control the device, process data, and transmit data wirelessly via at least one network to at least one remote computing device for analyzing the multiple biosignatures and cross-correlation with at least one external factor resulting in the creation of personal and situation profiles for continued on-going real time monitoring, refinement, alerting, and action recommendations.