A sampling device for collecting and dispensing a sample is disclosed, the sampling device including a sample collector having an absorbent portion configured to collect a sample and a receiving section configured to receive the sample collector after the collection of the sample. In one embodiment, the receiving section includes a dropper, the sample collector configured to be secured to the dropper, the dropper defining an internal chamber in which the absorbent portion of the sample collector is received when the sample collector is secured to the dropper; and a base releasably engaged with the dropper and at least partially housing the dropper, wherein the dropper is configured to be released from the base to allow dispensing of the sample from the dropper. In one embodiment, the absorbent portion interferes with a surface of an internal chamber of the receiving section. In one embodiment, a length adapter for the sample collector is employed and, in another embodiment, a desiccant housing is employed.

The present invention provides a biosensor and an application of the same. The biosensor includes a substrate, a first polymer layer and a second polymer layer. The first polymer layer includes composite antibodies, each of which includes a first antibody and a labelling molecule. The second polymer layer has an inverse opal photonic crystal structure where gold nanoparticles and second antibodies are distributed. At least one of the composite antibodies, an antigen and at least one of the second antibodies forms a complex in the second polymer layer, and an antigen concentration is obtained by a fluorescence intensity, a degree of red-shift or a change in a visual color of the biosensor.

An ophthalmic lens with glucose sensitive pad to indicate body glucose levels by changing color when in contact with tears from the eye includes a matrix, the matrix comprising a contact surface, the contact surface defining a micro-channel; and at least one glucose sensitive pad received in the micro-channel. A method for manufacturing an ophthalmic lens with glucose sensitive pad is also provided.

This disclosure describes devices and methods used to inject or aspirate fluid into or from various regions of the human body, such as the anterior chamber of the eye. The disclosed devices and methods provide improvements over conventional devices and methods in that an operator can perform a procedure using the disclosed device without an assistant. The disclosed devices and methods allow one-handed injection or aspiration of fluid into or from body tissue, and provide means for controlling the volume of injected or aspirated fluid.

The present disclosure relates to a body fluid collection device (1), the body fluid collection device (1) comprises a tube body (10), wherein the tube body (10) is used to contain the collected body fluid and is provided with an opened end (12); a tube plug (20), wherein the tube plug (20) is configured to be able to hermetically close the opened end (12) of the tube body (10); and a filter (30), wherein the filter (30) is arranged in the tube body (10) for filtering out specific components from a body fluid to be collected, wherein the filter (30) is configured to be capable of being attached to the tube plug (20) at the open end, and the tube plug (20) is hermetically connected to the filter (30).

Systems, methods, and devices for measurement of the osmotic pressure of fluids and, more particularly, to improving the measurement accuracy and precision of the osmolarity of the tear film. The approaches described herein improves upon the existing art of tear film osmometry to provide better performance in the presence of environmental instability.

This disclosure describes devices and methods used to inject or aspirate fluid into or from various regions of the human body, such as the anterior chamber of the eye. The disclosed devices and methods provide improvements over conventional devices and methods in that an operator can perform a procedure using the disclosed device without an assistant. The disclosed devices and methods allow one-handed injection or aspiration of fluid into or from body tissue, and provide means for controlling the volume of injected or aspirated fluid.

A method of using an electrochemical device includes at least first and second electrodes; a chamber for receiving a fluid sample and defining a volume partially bounded by a first portion of the first electrode and a second portion of the second electrode, the first portion having a first characteristic for influencing an electrochemical reaction at the first portion, the second portion having a second characteristic for influencing an electrochemical reaction at the second portion, the first and second characteristics having a predetermined relationship. The method also includes receiving a fluid sample in the chamber; measuring first and second electrical outputs at least one of the first and second electrodes; and determining whether the first and second electrical outputs are related according to the predetermined relationship.

Devices and methods for microbiome sampling and evaluation are disclosed. Devices including a capture substrate having first and second regions suitable for first and second analytic methods, respectively, are disclosed. Methods for collecting the microbiome sample with such devices are disclosed. Methods of evaluating the microbiome sample collected with such devices are disclosed. Kits including the devices for sampling and evaluating microbiome samples are also disclosed.

We disclose a medical toilet that comprises one or more medical devices and a control for the metrics they collect. The medical devices may be used to collect metrics relevant to a user's health status. The medical toilet further comprises a conduit through which volatile organic compounds travel from the toilet bowl to the environment outside the toilet. An animal trained to identify the scent of bodily waste collected from a user that is afflicted with a disease perceives the scent of the user's bodily waste traveling through the conduit and performs a defined act upon perceiving the disease scent. The metric collected by the medical device(s) may be used to diagnose the same disease as that which the animal is trained to identify. The diagnosis provided by the animal by way of the conduit acts as a control for the metric collected by the medical device.