The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.

A sexual assault evidence collection kit that may be used by the victim or other non-professionals. The kit may be simplified compared to kits for professional use, and may be usable with no specialized training. Victims may therefore be able to collect evidence themselves after an assault, instead of searching for a facility with personnel trained in forensic evidence collection, and enduring a long, intrusive examination. Embodiments may include a package (for example a clear bag) and the following components inside the package: gloves, swabs, swab containers, water, evidence collection bags, evidence bag sealing tape, evidence collection tape, a permanent marker, and instructions on how to identify, collect, seal, document, and store evidence.

A device to collect a biological sample may generally include an elongated rod having a handle and terminating in a tip; and a core and a plurality of projections extending in a radial direction from a surface of the core. The projections may have curved geometric pattern, such as a sinusoidal pattern, a circular arc pattern, and/or a helical pattern, for example. The device may include a layer of fibers disposed on a surface of the projections by flocking. Method of making and using the device are also described.

The present disclosure provides a female reproductive system sample collector, including a sampling device and an elution preservation device, where the elution preservation device is filled with an elution preservation solution, after sampling is completed, the sampling device is submerged in the elution preservation solution of the elution preservation device and sealed for preservation; the sampling device includes a sampling rod and a sheath; the sampling rod includes an operating rod, a straight rod brush and a ball head brush, an opening and closing cover corresponding to the ball head is disposed at a front end of the sheath, and the opening and closing cover includes four oscillating rods that are hinged with a front port of the sheath and the oscillating rods are connected through thin films. The present disclosure can collect cells or nucleic acids of uterus and ovaries in a uterine cavity, a sampling rod can deform in a shape along an outline of the uterine cavity. The sampling rod can avoid sample falling when finishing sampling and recovering; an elution preservation device can prevent liquid from overflowing and leaking or polluting a sealing cap. The present disclosure provides a quick, convenient, widely applicable and less discomfort sample collection channel and a sample protection method for early detection of the ovarian cancer, the endometrial cancer and the cervical cancer.

Efficient harvesting of cells, cell fragments, free nuclei, and DNA material from female reproductive system is made possible by processing gelatinous part of cervical mucus. Rinsing may be used to separate the gelatinous part of cervical mucus from the remainder of the cervical mucus sample.

Inventive embodiments disclosed herein include a sampling device. The sampling device includes a tubular main body having a length and defining a lumen, the tubular main body defining a lumen that extends the length of the tubular main body, the tubular main body having a distal end sized for insertion into a body cavity and having a proximal end defining threads; and a flexible sample container, comprising threads for engagement with the tubular main body wherein the lumen of the tubular main body is in communication with the flexible sample container when the container is engaged.

Bodily fluid indicator devices and methods are provided. Such devices and methods can effectively indicate whether the amount of bodily fluid being produced is within a measurable range. In an exemplary embodiment, a bodily fluid indicator device includes a substrate having a surface. Some portions of the surface are covered with a region of absorbent material and other portions of the surface are devoid of the absorbent material. A graduated scale or a reactive feature is printed on the absorbent material. The device is configured to indicate an amount and/or a composition a bodily fluid present on an area of a patient or subject.

A cervicovaginal fluid collection device comprising: a generally tubular housing, a first end of the housing comprising an enclosed tip and a number of through holes provided at the enclosed tip; a probe provided within the housing, a first end of the probe provided with a screw-like structure, the screw-like structure having a sliding fit with an inner bore of the housing, at least a first end of the screw-like structure provided at the enclosed tip of the housing; and a fluid-absorbing swab provided on the probe within the housing adjacent a second end of the screw-like structure to absorb fluid drawn into the housing; wherein rotation of the screw-like structure relative to the housing draws fluid that is adjacent and exterior to the enclosed tip of the housing into the housing through at least one of the through holes; and wherein fluid drawn into the housing is absorbed by the fluid-absorbing swab.

The present invention provides a device that can move inside a biological conduit such as an intestinal tract for sampling the content therein, and a process thereof. While moving along the intestinal tract, the device can continuously collect the content in the intestinal tract. One or more convoy belts having an adsorbent layer are configured to continuously absorb and preserve the collected intestinal content. The belt loaded with the sample may be used to establish a chemical, biochemical and microbiological spectrum along the length of the intestinal tract.

A vaginal fluid monitoring device includes an absorbent layer, wherein the absorbent layer is configured to be in proximity to flow of vaginal fluid; an electrochemical detection system configured to obtain data regarding at least one analyte in a vaginal fluid, said electrochemical detection system in fluid communication with the absorbent layer; and wherein the vaginal fluid monitoring device is configured to be coupled with a feminine hygiene product.