The embodiments presented herein present a single needle core biopsy instrument and modification required that convert the single needle core biopsy instrument to a dual needle core biopsy instrument. Depending on the design, the dual needle core biopsy instrument permits the simultaneous extraction of tissue or bone specimens taken at between 0.1 mm and 3 mm apart.

A biopsy forceps device includes a tension member and an end effector including first and second jaws movable between an open configuration, in which the jaws are separated from one another to receive target tissue therebetween, and a closed configuration, in which cutting edges of the jaws are moved toward one another to cut a portion of the target tissue. The jaws define a tissue receiving space therebetween to house the cut tissue. The jaws are pivotable relative to one another, each of the jaws including a serrated cutting edge extending therealong, the end effector further including a tension member attachment including a proximal end coupled to the tension member. The attachment is movably coupled to the jaws so that distal movement of the attachment moves the jaws to the open configuration while proximal movement thereof moves the jaws to the closed configuration.

A biopsy system includes a biopsy device, a control module, and a tissue transport tube. The biopsy device includes a probe, a needle, a cutter, and a transport valve. The needle extends distally from the probe. The cutter is movable relative to the needle and defines a cutter lumen. The holster is configured to couple to the probe. The transport valve is in communication with the cutter lumen. The control module is in communication with the biopsy device and includes a sample management assembly configured to receive one or more tissue samples severed by the cutter. The transport tube extends between the sample management assembly and the biopsy device. The transport tube is in communication with the transport valve such that the transport tube is configured to receive the one or more tissue samples severed by the cutter.

A biopsy needle arrangement comprises a needle sheath and a needle. The biopsy needle arrangement is configured to be operatively connected to an actuator device configured to push the needle and the sheath distally in a sliding direction x. The biopsy needle arrangement further comprises a needle connector configured to attach the needle to the actuator device and a sheath connector configured to attach the needle sheath to the actuator device. The needle connector is configured to disengage the needle from the actuator device when the needle is subjected to a force in the sliding direction, which exceeds a threshold force. Also or alternatively, the sheath connector is configured to disengage the needle sheath from the actuator device when the needle sheath is subjected to a force in a direction opposite the sliding direction, which exceeds a threshold force.

Medical devices and methods for removing a predetermined portion of soft tissue from a target tissue layer, thereby creating a channel between two side walls of the target tissue layer, are described. The medical device is a cutting tool comprising: an elongated round body extending along a longitudinal axis and having a uniform outer cross-section at a proximal side thereof; a cutting portion at a distal side of the elongated body, comprising at a distal end thereof a cutting edge of a first cross-section being smaller than said outer cross-section, and a distally and continuously decreasing outer cross-section; and a chamber extending along the longitudinal axis inside the cutting tool from said cutting portion, the chamber having dimensions enabling storing of the removed soft tissue portion inside the chamber thereby providing a validation to the channel creation.

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject).

A biopsy and therapy device comprising: a needling unit for holding and inserting a biopsy needle; an imaging module comprising an ultrasound probe and an actuator for moving the probe in a reciprocal action; a first arcuate slide; a second arcuate slide in sliding engagement with the first arcuate slide and a linkage to which the first arcuate slide is mounted; said linkage arranged to move the first and second arcuate slides within a vertical plane; said needling unit mounted to said arcuate slide wherein the first and second arcuate slides are mounted perpendicular to each other so as to rotate the needling unit about respective first and second principal axes.

A platform device for material excision or removal from vascular structures for either handheld or stereotactic table use may comprise a work element or elements configured to selectively open and close at least one articulable beak or scoopula configured to penetrate and remove intra-vascular materials or obstructions, or follow a central lumen of another device or over a wire in a longitudinal direction. Flush and vacuum tissue transport mechanisms may be incorporated. A single tube or an inner sheath and an outer sheath which may be co-axially disposed relative to a work element may be configured to actuate a beak or beaks or scoopulas and provisions for simultaneous beak or scoopula closing under rotation may be incorporated.

A device including a probe unit and a driver unit for tissue extraction and sample collection is disclosed. The probe unit includes an injection unit, a driving mechanism, a filtering mechanism and a tissue sample container. The injection unit includes a needle actuated by a prime-mover and the driving mechanism, which drives the needle into the subject for extraction of tissue sample. The tissue extraction is performed by a rotational motion of the needle and pressure. The pressure is provided by a pressure subsystem in the lumen of the needle and the tissue is collected in the tissue sample container. The amount of pressure applied is controlled by a control subsystem based on the organ specific requirement.

A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described, as well as alternative systems for tissue preservation and transport. The cutting device includes an outer cannula in which a reciprocating inner cannula is disposed. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. A temperature control sleeve may be disposed around the tissue collector to control the temperature of the tissue samples. A preservation system may be supplied that is configured to deliver fluids to tissue samples in the tissue collector. A fluid supply sleeve may be disposed about the outer cannula and is selectively positionable along the length of the outer cannula.