The present disclosure provides a fluidic device including a first inlet, an outlet, and a channel positioned between the first inlet and the outlet. The channel is in fluid communication with the first inlet and the outlet. The fluidic device further includes a second inlet positioned between the first inlet and the outlet. The second inlet is in fluid communication with the channel. The fluidic device further includes a pump in fluid communication with the second inlet. The pump is configured to provide a first volume of pulsatile flow to the channel The first volume of pulsatile flow is greater than about 50 μL per pulse.

An impact biopsy device is disclosed. The impact biopsy device may be configured to displace various cutting elements, such as an outer tubular member and cutting element and a cannula to sever a tissue sample from a patient. The impact biopsy device may comprise an actuation system configured to transfer displacement or force to the cutting elements by the impact of an element on another element.

Limited physical access to target organs of patients inside an MRI scanner is a major obstruction to real-time MRI-guided interventions. Traditional teleoperation technologies are incompatible with the MRI environment and although several solutions have been explored, a versatile system that provides high-fidelity haptic feedback and access deep inside the bore remains a challenge. A passive and nearly frictionless MRI-compatible hydraulic teleoperator is provided designed for in-bore biopsies. A needle driver translates a needle in insertion and retraction directions via a clutch mechanism. A needle holder grips the needle via a retraction lock when the clutch mechanism of the needle driver releases the needle to hold a position of the needle during reposition of the needle driver.

A biopsy device includes an elongated handle body having a proximal end portion and a distal end portion, a needle disposed within the handle body, first and second transducers, and a display. The needle is configured to move between a retracted position and a deployed position. The first and second ultrasound transducers are disposed within the distal end portion of the handle body. The first and second ultrasound transducers are angled relative to one another and define a space therebetween configured for passage of the needle.

In various embodiments, a medical device comprises a trocar including an awl and a cannula; two or more electrodes disposed on a distal portion of the trocar; an impedance bridge coupled to the two or more electrodes; and a processor coupled to the impedance bridge. In various embodiments, a computer-implemented method for evaluating tissue of a patient comprises recording, at one or more frequencies, one or more impedance measurements, wherein each impedance measurement is associated with two or more electrodes disposed on a distal portion of a trocar; comparing the one or more impedance measurements to one or more characteristic impedances associated with one or more tissue types; and determining, based on the one or more impedance measurements and the one or more characteristic impedances, one or more tissue types at a location associated with the distal portion of the trocar.

The application relates to a sample holder (110) and a system (100). The application also relates to a method for processing a biological sample (S) and use of the sample holder or of the system in an analytical method or a diagnostic method. The sample holder (110) comprises a tubular member (111) with a wall that is at least locally transparent and at least locally permeable for reagents, wherein the tubular member consists at least partially of a transparent material.

Embodiments include methods, systems, and apparatus for identification, detection, and removal of cancerous cells from a patient. The apparatus includes an apparatus handle. The apparatus also includes a display including a pH measurement result. The apparatus also includes an apparatus tip including a reference electrode and a plurality of sensing surfaces, wherein each of the plurality of sensing surfaces is connected to a base of a bipolar junction transistor (BJT) device. The BJT device further includes a collector and an emitter. The apparatus also includes automation circuitry including a processing unit in communication with the apparatus tip and the display. The plurality of sensing surfaces includes a conducting material.

A method of spectrometric analysis comprises obtaining one or more sample spectra for an aerosol, smoke or vapour sample. The one or more sample spectra are subjected to pre-processing and then multivariate and/or library based analysis so as to classify the aerosol, smoke or vapour sample. The results of the analysis are used for various surgical or non-surgical applications.

An insertion tool guide for a medical procedure like a biopsy. The tool guide includes (a) a frame configured to be adjoined to a medical image modality and maintain an insertion angle aligned with a plane of view generated by the medical image modality; (b) a guide body having an adjustable channel configured to receive and translate an insertion tool; (c) a main channel defined by the frame configured to allow the guide body and the insertion tool to rotate within a plane of movement; (d) a guide channel formed along one side of the frame configured to allow the guide body to translate along its length; and (e) a peg extending from the guide body and through the guide channel to secure the guide body within the frame. The guide body is configured to rotate about an axis defined by the peg.

A breast biopsy lateral arm system includes a removable gun mount which attaches to a carriage that traverses along an X-axis defined by a lateral arm in order to position a biopsy needle relative to a patient. The carriage rides along the lateral arm on self-adjusting rollers which are loaded against the lateral arm by spring members. A cam-actuated carriage slide lock can be used to secure the carriage in a desired position relative to the lateral arm. A cam-actuated removable gun mount lock allows the gun mount to be quickly changed and offset orthogonally with respect to the X-axis. An X-axis stop can be used to establish a position to which the carriage can be returned with accuracy.