The present invention relates to a device for collection of tissue cells from a cervical face and endocervical canal of a uterus which material to ensure elasticity, adhesion of cells to the surface for collection, and comfort for the patient. The assembly provides elastic material to affix the cell collection surface to the rod with bristles rather than traditional rigid mechanical clamps, use of three distinct types of bristles specialized for collecting cells from each of the cervical os, use of a single elastic material for the brush bristles and for affixing the cell collection surface to the shaft/rod. The assembly also ensures protection of the collected cell specimens from contamination by inversion of the elastic bristle-bearing material prior to removal from the vagina.

The invention relates to trans-epithelial frictionally abrasive tissue sampling devices for performing biopsies and methods of inducing an immune response against a pathogen, wherein epithelial cells containing the pathogen are disrupted with the frictionally abrasive tissue sampling device to introduce the pathogen into the bloodstream of a patient.

An accessory sleeve and a method for use is provided. The accessory sleeve includes a cylindrical sleeve body. The cylindrical sleeve body includes an outer surface, an inner surface, the inner surface defining a hollow sleeve channel, and at least one open end. The sleeve body is configured to receive an insertion portion of a medical speculum in the hollow sleeve channel, and the sleeve body is further configured to expand from a first state to a second state.

A polyp removal device includes an outer tubular body; an inner tubular body; a tubular cutter coupled to or formed as part of the distal end of the inner tubular body; a spring positioned to bias the inner tubular body in an extended direction with respect to the outer tubular body; a handle coupled to the proximal end of the outer tubular body; an actuation member movably coupled to the handle; and a disconnect mechanism for selectively coupling the actuation member to the inner tubular body and decoupling the actuation member from the inner tubular body, the disconnect mechanism is configured to automatically decouple the inner tubular body from the actuation member when the actuation member is moved in a first direction for a distance greater than a predetermined distance.

The present disclosure generally relates to devices, systems, and methods for Fallopian tube diagnostics. In some embodiments, a tube may have a distal end, and a balloon may be coupled to the distal end of the tube. The balloon may be disposed in the tube in a first, inverted position and movable to a second, everted position. The balloon may be extendable a distance distal of the tube distal end such that a surface of the balloon is contactable with an inner surface of the Fallopian tube. A push wire may have a distal end coupled to a second end of the balloon. The balloon may be movable from the first inverted position to the second everted position by actuation of the push wire. The surface of the balloon may include a plurality of surface features for collection of a tissue sample of the inner surface of the Fallopian tube.

The present invention relates to an implant, an ovarian cancer screening test kit comprising same, and an ovarian cancer screening test method using same, thereof wherein the implant is mounted in the uterine cavity so that the working channel maintain a path from the cervix to the fallopian tube for a predetermined period. According to the implant for screening test of ovarian cancer, the screening test kit comprising same, and the ovarian cancer screening test method using same of the present invention, the implant mounted in the uterus can be used to execute the screening test, can simply carry out periodically repeated screening tests to improve the convenience and minimize discomfort for the patient, and can allow both cystoscopy and biopsy.

A tissue biopsy device includes an inner drive assembly, an outer tube, and an inner cutting member extending through the outer tube. The inner drive assembly is coupled to both the outer tube and the inner cutting member and is configured to receive a rotational input. In response to receiving the rotational input, the inner drive assembly is configured to alternatingly distally translate the outer tube and the inner cutting member.

A tissue biopsy device includes an input configured to receive a rotational input and to rotate in a first direction in response thereto, an outer tube, and an inner cutting member extending through the outer tube. A mechanism couples the input with at least one of the inner tube or the outer tube and/or one of the inner tube or the outer tube is coupled to the input such that rotation of the input in the first direction drives rotation of the one of the outer tube or the inner cutting member in the first direction and drives rotation of the other of the outer tube or the inner cutting member in a second, opposite direction.

A tissue biopsy system includes a biopsy needle having an elongated shaft with a distal tip configured to pierce and capture a sample of tissue. The elongated shaft includes a needle bore defined therein having a helical feature defined along an inner periphery thereof. Upon rotation of the biopsy needle and insertion of the biopsy needle into tissue, the helical feature of the needle bore advances tissue proximally into the needle bore for containment and retention.

The present invention comprises methods and devices comprising a cutting element used to contact circumferentially and longitudinally the surface walls of the endocervical canal to provide for broad and complete contact of the intended surface with the device, resulting in attainment of a sufficient volume and comprehensive tissue sample for analysis as an endocervical curettage or screening pap smear. The device may provide for a reservoir for the obtained sample to be contained when removing from the cervical canal and vagina. The device may be comprised of a detachable means or be of a material that allows the user to cut the sampling head of the device for placement in collection means to maximize the amount of tissue or cells being sent to the laboratory for analysis.