The present disclosure is directed to systems and methods for endovascular electroencephalography (EEG) and electrocorticography (ECoG) systems. In some embodiments, the disclosed systems include electrode arrays that are configured to record and/or stimulate brain tissue via placement within blood vessels of the brain. Venous and arterial EEG and ECoG electrodes, ambulatory EEG and ECoG systems, and transcutaneous access and signal control systems for general and ambulatory endovascular electroencephalography (EEG) and electrocorticography (ECoG), as well as endovascular neural stimulating electrodes are discussed.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

A multi-layer, super-planar laminate structure can be formed from distinctly patterned layers. The layers in the structure can include at least one rigid layer and at least one flexible layer; the rigid layer includes a plurality of rigid segments, and the flexible layer can extend between the rigid segments to serve as a joint. The layers are then stacked and bonded at selected locations to form a laminate structure with inter-layer bonds, and the laminate structure is flexed at the flexible layer between rigid segments to produce an expanded three-dimensional structure, wherein the layers are joined at the selected bonding locations and separated at other locations. A layer with electrical wiring can be included in the structure for delivering electric current to devices on or in the laminate structure.

This device includes a propulsion element including at least one portion deformable in elongation/contraction according to a main axis (X.sub.2) connecting a front portion and a rear portion. At least two guide elements adapted to generate, under the effect of an energy supply, a rotation of the propulsion element respectively about a first axis of rotation and about a second axis of rotation transverse to each other and to the main axis (X.sub.2) of the propulsion element. A control unit configured to actuate a rotation of the propulsion element about at least one axis transverse to the main axis (X.sub.2) in a coordinated manner with a deformation of the deformable element of the propulsion element in elongation/contraction according the main axis (X.sub.2).

The present disclosure relates to a method for locomotion of at least one nanorobot through a biochemical environment. The present disclosure also reveals a method for locomotion of nanorobots for use in drug delivery, delivery of materials for medical imaging and medical diagnosis.

Disclosed is a catheter system. The catheter system includes: a catheter module including a catheter and a first fastening magnet coupled to a tip of the catheter; and a magnetic robot including a second fastening magnet magnetically coupled to the first fastening magnet, and coupled to and released from the catheter module.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

A microrobot is disclosed. The microrobot comprises: a rotating shaft; a main magnet fixed and coupled to the rotating shaft; a first support body which is inserted into the rotating shaft and which is rotatable around the rotating shaft; a first driving magnet which is fixed and coupled to the first support body and which has a magnetic moment differing, in size, from that of the main magnet; and a plurality of first legs coupled to the outer circumferential surface of the first support body.

A magnetically controllable robotic device including a body having a first body part and a second body part movably connected with the first body part. The first body part and the second body part are both rigid. The first body part is magnetically-responsive such that the first body part can be controlled by an external magnetic field generated by an magnetic control system. The first body part may be controlled such that the magnetically controllable robotic device is moved by the external magnetic field.

A system for controlled sympathectomy procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. An implantable device for monitoring and/or performing a neuromodulation procedure is disclosed.