A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes an expandable structure for enhancing engagement with median lobe prostate tissue.

The disclosure relates generally to devices and methods for treating a tissue defect, for example, by suturing. In some embodiments, a suturing device may include an elongate member having a working channel, a suture channel, and a suture arm extending from the elongate member. The suturing device may further include a needle passer located within the working channel, the needle passer operable to deliver a needle between the elongate member and a distal end of the suture arm for suturing a target tissue, and a suture extending through the suture channel, wherein the suture is coupled to the needle. The suturing device may further include a plurality of imaging devices, wherein a first imaging device is positioned along a distal face of the elongate member, and wherein a second imaging device is positioned along the suture arm.

A device includes an elongated hollow member having an open distal end for receiving tissue therein and at least one exterior groove for loading at least one ligation band thereon. The device also includes a band deployment sleeve slidable over the exterior of the hollow member and configured to move from a radially expanded position to a radially contracted position in which, when the band deployment sleeve slides longitudinally over the hollow member, the distal portion engages the at least one ligation band. A closing sleeve slidable over the exterior of the band deployment sleeve is configured to constrain the distal portion from the radially expanded position into the radially contracted position. Retracting the closing sleeve proximally over the distal portion of the band deployment sleeve releases the distal portion from the radially contracted position into the radially expanded position.

A tissue traction device, system, and method presenting a grasping rail for coupling with a portion of a target tissue at a treatment site to apply a force, such as traction, to the grasped tissue, such as to facilitate performance of a procedure on the target tissue. A tissue traction device, system, and method having a distal support element, a proximal support element, and at least one expansion element extending therebetween. The at least one expansion element is extendable to define a working area for a procedure to be formed on target tissue at a treatment site. Two or more expansion elements may define a working area unimpeded by the expansion elements. The distal support element may be expandable to anchor the tissue traction device with respect to tissue.

A tissue displacing and fastening device is provided for manipulating and fastening tissue together. The device includes a tissue displacing elements, which displaces tissue. A fold is formed from the displaced tissue and the tissue is fastened together to secure the fold.

Disclosed herein is a percutaneous catheter apparatus, comprising two nested needles; and an inner plunger; which is guided as a catheter to the tissue surrounding a hard implant to actuate and deploy a pair of sharp-tip needle-forceps that perform two concentric cuts, circularly spaced 90-degree apart from each other, to complete a 360 degree bore around the implant before squeezing to arrest and extract the implant, together with its surrounding tissue.

Valve repair systems and clips for attachment to one or more leaflets of a heart valve. The clip can include an elongated member configured to be positioned between two leaflets of the heart valve. The elongated member can have a first portion and a second portion that extends from the first portion. A width of the second portion can be greater than the width of the first portion. A pair of arms can be coupled to the first portion and extend toward the second portion. The pair of arms can extend radially away from the elongated member as the pair of arms extend away from the first portion toward the second portion when the arms are in an open position. And the pair of arms can be moveable from the open position to a closed position to pinch each leaflet between one of the arms and the elongated member.

A circular stapling device includes a reload assembly having a housing, an annular staple cartridge, and grasping members. The housing and the staple cartridge define channels that receive the grasping members. The grasping members are movable through the channels between retracted and extended positions to grasp tissue and pull the tissue into the housing during an anastomosis procedure.

A needle and suture assembly is provided for use with an endoscopic suturing device with a needle holder arm. The needle assembly includes a needle tip and a needle body. The needle tip has a sharp end, a capture groove, a tab groove and a plug portion positioned between the capture groove and the tab groove. The needle body has first and second ends, tip tabs, retainers for removably retaining the needle body relative to the needle holder arm, and a suture opening. The needle tip is fixed relative to the needle body by plastic deformation of the tip tabs into the tab groove. A suture extends into the suture opening of the needle body and is fixed therein.

An ophthalmic surgical instrument for cataract removal surgery includes a helical coil structure including a wire or elongated structure coiled in a plurality essentially similar diameter coils of 360-degree turns in a corkscrew having a coil diameter sufficiently small to fit within an incision of a human ocular lens capsule for entering the human ocular lens capsule during a cataract removal surgery. A pointed sharp end pierces and grasps a human ocular lens under the control of a surgeon upon being inserted in a human ocular lens capsule within said ocular lens capsule during a cataract removal surgery. The corkscrew structure firmly holds the human ocular lens and controls the position and movement of the human ocular lens during said cataract removal surgery.