The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

A medical device includes a handle that includes a handle body longitudinally extending from a proximal end to a distal end; a distal connector configured to connect to a proximal end of an elongate outer member; a lumen longitudinally extending through the handle body, the lumen configured to have an elongate inner member movably disposed therein, and to permit the elongate inner member to distally extend past the distal end to within the elongate outer member and to proximally extend past the proximal end; and an inner member controller configured to longitudinally move relative to the handle body to control movement of the elongate inner member relative to the elongate outer member. The handle may be a distal handle of the medical device, which further includes a proximal handle. Both handles may control movement of the elongate inner and outer members.

The present subject matter provides a system for allowing controlled access of a tool to all sides of an elevated tissue in body of a patient, the system including: a rail configured to surround the elevated tissue; and at least one vehicle configured to move along the rail and carry at least one tool configured to manipulate the elevated tissue. Also provided is a method for cutting an elevated tissue in a body of a patient, the method including: inserting a rail to a vicinity of the elevated tissue; surrounding the elevated tissue with the rail; placing a vehicle on the rail; connecting a cutting device to the vehicle; and moving the vehicle along the rail while cutting the elevated tissue with the cutting device. Additional embodiments of the system and method are disclosed herein.

An endoscopic catheter assembly including a catheter portion is disclosed. The catheter portion includes a proximal portion and a distal portion. The catheter portion includes a tube-shaped body defining a passage extending there-through.

Embodiments of the invention include instruments (100, 200, 400, 1100, 1400, 2100, 2400, 3400) and methods useful in delivering graft material (1) to a surgical site. Some embodiments may particularly be directed to forming a graft (1) and accurately and effectively handling and delivering the graft (1) to a surgical site arthroscopically. Graft material (1) may include blood components such as clotted fibrin derived from a patient's or a donor's blood.

An implantation and/or retrieval device for a leadless cardiac pacing device may include a first elongate shaft including a lumen; a second elongate shaft slidably disposed within the lumen of the first elongate shaft; an end cap assembly fixedly attached to a distal end of the first elongate shaft; and a plurality of wires attached to the second elongate shaft and extending distally from the end cap assembly, the plurality of wires being movable relative to the end cap assembly. The plurality of wires is configured to engage a proximal hub of the leadless cardiac pacing device. The plurality of wires forms a plurality of wire loops extending distally from the end cap assembly.

An endoscopy instrument is configured to be adjustable between a retracted position and an extended position. The endoscopy instrument includes a snare forming a loop extending from a proximate end to a distal end and a plurality of basket wires. Each of the basket wires includes a proximate end coupled to the proximate end of the snare and a distal end coupled to the distal end of the snare. The snare and the plurality of the basket wires cooperate to form a basket portion configured to contract when the endoscopy instrument is adjusted from the extended position towards the retracted position during entry of the basket portion into a tubular member. The contracting of the basket portion aids in grasping an object in need of retrieval from a patient.

A containing element is used to capture material in a blood vessel for removal. The containing element is positioned within a constraining catheter while it is advanced through the blood vessel. A filament is coupled to the containing element which assists in opening and/or closing the containing element.

Devices and methods for increasing or restoring a flow in a body lumen. The devices and the methods may treat conditions like stroke by removing a clot from a blood vessel and/or reopen the vessel. The device may include a plurality of engaging elements, a central wire, and proximal control element. The device may include a linking structure between engaging elements. The linking structure may include segments configured to respond differently upon the application of longitudinal loads. The positions of the engaging elements and the distance therebetween can be adjusted simultaneously or sequentially to promote the engagement of the clot or occlusion. The device may include be configured to inhibit or prevent the proximal engaging element from being pulled back into a microcatheter when pulling the central wire to pull the distal engaging element proximally and/or during retraction of the device holding a clot.

An endoscope treatment tool includes: a sheath; an operating wire in the sheath; a gripping portion provided at a distal end of the operating wire and having one or more wires; a tip attached to a distal end of the sheath; and a resin member disposed at a position adjacent to the tip on a radially inner or outer side thereof, wherein the tip includes clearance grooves extending toward a proximal end of the tip from a distal end of the tip, passing therethrough from an inner circumferential surface of the tip to an outer circumferential surface of the tip, and having sizes enabling the wires to pass therethrough, and at least proximal-end sides of the grooves overlap with the member in a radial direction of the tip and a distal end of the member is disposed farther on a distal-end side than proximal ends of the grooves are.