An apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. The tissue connectors are connected to a base which allows for easy adjustment of the tissue connectors along a cord. The base includes a locking mechanism which impinges a sliding knot in the cord, and, in alternate configurations of the locking mechanism and knot, impinges on the sliding knot to prevent sliding in a loosening direction but allow sliding in a tightening direction, or allows sliding in a loosening direction.

A suture delivery device includes a base portion and a deployment portion extending from the base portion. The base portion defines a longitudinal axis. The deployment portion includes a plurality of petals extending along the longitudinal axis parallel to one another when the deployment portion is in a delivery position and extending radially outward from the longitudinal axis when the deployment portion is in a deployed position.

A retrieval device comprising a hook assembly and a capsule assembly. The hook assembly has an attachment feature at a first end. The capsule assembly includes a capsule, a capsule shaft, and a handle connected in series and defining an inner bore. The capsule has a first end defining an opening. The inner bore of the capsule assembly is configured to slidably receive the hook assembly. The handle has a central portion, a first extension portion attached to the capsule shaft, and a second extension portion with a hook assembly lock at a second end. The hook assembly lock is configured to lock the hook assembly to the second extension portion. The second extension portion is configured to pull the hook assembly relative to the capsule shaft, and the first extension portion is configured to push the capsule shaft relative to the hook assembly along the central longitudinal axis.

A uniportal surgical device having a slotted clear cannula, a blade and a housing, wherein the cannula is attached to the housing, and wherein the blade is enclosed in the housing and is slidable into the cannula is disclosed. The device further has a device for locking a viewing device in place relative to other components of the device. A method for a performing an operative procedure on a target tissue in a subject using the uniportal surgical device is also described.

A robot configured for mini-invasive surgery through a single parietal incision and/or natural orifice includes at least one articulated support, a stiffening component, and at least one maneuvering element. The articulated support includes a plurality of rigid bodies that are mutually associated. The stiffening component is associated with the articulated support and adapted for the transition of the articulated support from an inactive configuration, in which the rigid bodies can move with respect to each other, to an active configuration, in which the rigid bodies are mutually aligned so as to form a guide, and vice versa. The least one maneuvering element can be associated slidingly with the guide of the articulated body in its active configuration and can engage selectively a plurality of operating instruments accommodated in at least one container body that can be associated with the articulated support in its active configuration.

Devices and methods for organizing a plurality of end effectors and selectively delivering them through surgical trocars are described herein. In one embodiment, a surgical end effector loading device is provided that includes at least one mating element to interface with a surgical trocar, a deployment lumen positioned to align with a working channel of a surgical trocar, an end effector repository having a plurality of end effector lumens formed therein to receive end effectors, the repository being configured to selectively align any of the plurality of end effector lumens with the deployment lumen, and an advancer coupled to the repository and configured to advance an end effector from the repository through the deployment lumen.

Described herein are various method of using a direct drive system to perform procedures at a distance. One exemplary method include tying a knot or suturing at a distance with a first and second end effector. The direct drive system can enable sufficient end effector dexterity, including the ability to control various degrees of freedom of end effector movement, and allow a user to perform complicated task at a distance. In one aspect the direct drive system includes flexible tools that permit access to surgical site via a natural orifice.

The present invention relates to devices and methods for use in minimally invasive procedures whereby at least one, and preferably a plurality of laparoscopic instrument heads can be delivered through a single trocar and made accessible for attachment within a body cavity to the distal end of a needlescopic instrument under direct visualization via a laparoscope. The system and procedure will produce less scarring, less pain, and a reduced risk of infection at the surgical site. An addition benefit is that, because only 1 trocar is used instead of 3-5 trocars, there is a significant cost saving in each case and the surgeon is freer to move instrument locations and add/remove instruments since a new trocar does not need to be inserted every time.

In accordance with one embodiment, a method of capturing biomatter includes placing a device comprising the biomatter within an extension tube, the extension tube being coupled to a tray. A fold is created in the extension tube sealing the extension tube and the biomatter contained therein. The extension tube is secured to the tray to maintain the fold. The assembly is discarded, e.g., into a bio-waste disposal bag in a bio-waste container. The fold is a smooth fold, in contrast to a sharp tip, thus minimizing the possibility of puncture of the bio-waste disposal bag.

Disclosed are compositions, devices, systems, kits, and methods for neural ablation.