A loader for a surgical suturing instrument is disclosed. The loader has a head having a protrusion configured to be releasably held by a tissue bite area of a surgical suturing instrument. The loader also has a tube interface. The loader further has one or more ferrule holders. The loader also has one or more ferrules, each corresponding to and held by one of the one or more ferrule holders and coupled to a suture end that leads from a tube releasably held by the tube interface.

A surgical stapling apparatus includes a tool assembly, at least one surgical buttress, and a resilient, porous material. The tool assembly includes a cartridge assembly and an anvil assembly pivotably coupled to the cartridge assembly. The cartridge assembly includes a first tissue facing surface defining staple retaining slots. The anvil assembly includes a second tissue facing surface defining staple pockets for forming staples expelled from the staple retaining slots of the cartridge assembly. The at least one surgical buttress is releasably disposed on at least one of the first and second tissue facing surfaces. The resilient, porous material is releasably disposable between the first and second tissue facing surfaces and in contact with the at least one surgical buttress. The resilient, porous material is configured to expel a liquid therefrom upon compression thereof by an approximation of the cartridge assembly and the anvil assembly.

A stapling assembly comprising a tissue thickness compensator is disclosed. The tissue thickness compensator comprises a body portion comprising a porous material and a plurality of cavities defined in the body portion, wherein the cavities are aligned with forming surfaces of an anvil such that fasteners of a fastener cartridge are configured to at least one of the cavities when the fasteners are ejected from the fastener cartridge or capture the cavities and compress the cavities within the tissue thickness compensator when the fasteners are ejected from the fastener cartridge and formed by forming surfaces of the anvil. The stapling assembly further comprises at least one medicament positioned within each cavity prior to firing the stapler, wherein the medicament is different than the porous material.

A two-part tissue thickness compensator assembly can include a first tissue thickness compensator configured to be positioned relative to an anvil of a surgical stapler, a second tissue thickness compensator configured to be positioned relative to a staple cartridge of the surgical stapler, and a hinge connecting the first tissue thickness compensator to the second tissue thickness compensator. The first and/or second tissue thickness compensators may include additional engagement features, such as a raised ridge that engages a slot in the anvil and/or the staple cartridge. In certain embodiments, the first and/or second tissue thickness compensators may include an encasement that contains a suitable biologic agent. An end effector assembly may be provided for attachment to a surgical instrument that includes, for example, a staple cartridge, an anvil, a first tissue thickness compensator positioned on the anvil, and a second tissue thickness compensator positioned on the staple cartridge.

Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a delivery system for use in occluding an opening in the tissue of a body includes an actuation assembly operatively coupled to a medical device including an anchor portion and an occluder portion. The actuation assembly is configured to move the anchor portion between a deployed state and retracted state while the occluder portion maintains a deployed state. With this arrangement, the deployed occluder portion can be visualized via imaging at a preferred position prior to deploying the anchor portion of the medical device.

A staple cartridge comprising a tissue thickness compensator is disclosed. The tissue thickness compensator comprises an uncompressed height, a compressed height, an outer encasement, and tubular structures aligned along the longitudinal axis. The tubular structures are configured to collapse when pressure is applied to the tissue thickness compensator by tissue during the firing motion.

Described herein are systems, devices, and methods for closing a perforation in any hollow vessel associated with a mammalian surgical procedure, for example a device for sealing an aperture in a tissue, the device comprising an implant and a delivery shaft configured to engage the implant, the delivery shaft comprising (i) a retaining sleeve, (ii) a release sleeve, and (iii) a handle coupled to the delivery shaft.

A continuous strip of staples for use with a surgical stapling device includes an elongated stock of corrugated paper defining a plurality of channels therein. An inner facing side of each channel is configured to support a row of staples thereon and extending therealong and is configured to be slidingly received in a corresponding plurality of slots defined within a cartridge assembly of a stapling device for loading the staples therein. A plurality of indexing apertures is defined in the elongated stock and extends therealong. The plurality of indexing apertures is adapted to engage a staple deformation element of the cartridge assembly during retraction thereof to automatically reload one or more new rows of staples after actuation of the stapling device.

The present disclosure relates to an end effector instrument. The end effector instrument may include an end effector device. The end effector device may include a clip and a resilient portion including a connecting hole and a limiting convex. The end effector instrument may further include a delivery device including a sheath and a shaft. The sheath may include a passage that accommodates the shaft. A distal end of the shaft may include a connecting end. The sheath may include a limiting concave. The connecting end may extend into or exit from the connecting hole when the sheath is set outside the resilient portion: when the connecting end extends into the connecting hole, the resilient portion may expand outward, and the limiting convex may extend into the limiting concave; when the connecting end exits from the connecting hole, the resilient portion may rebound, and the limiting convex may exit from the limiting concave. The end effector device may be operated repeatedly, and the delivery device may be reused.

A surgical stapling assembly that includes a surgical stapling device that has a lockout that is movable between a locked position and an unlocked position. The assembly further includes a staple cartridge with a first cam surface configured to cammingly engage a primary portion of the lockout to move the lockout laterally from the locked position and a second cam surface configured cammingly engage a secondary portion of the lockout to further move the lockout laterally into the locked position when the cartridge is operably seated in the device.