Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.

An open-cavity, reduced-pressure treatment device and system for treating a cavity in a patient's body, such as an abdominal cavity, is presented. In one instance, an open-cavity, reduced-pressure treatment device includes a plurality of encapsulated leg members, each having an interior portion with a leg manifold member and formed with fenestrations operable to allow fluid flow into the interior portion, and a central connection member fluidly coupled to the plurality of encapsulated leg members. The central connection member has a connection manifold member. The open-cavity, reduced-pressure treatment devices, systems, and methods allow for, among other things, removal of fluids.

In some embodiments, an apparatus includes an introducer sheath and a dilator. The introducer sheath can include a body portion and a tip portion. The body portion can be coupled to the tip portion via a seal portion. The dilator can be configured to be inserted into a lumen defined by the introducer sheath such that the dilator can engage with the tip portion and translate the tip portion relative to the body portion such that the tip portion moves the seal portion from a biased neutral configuration to an extended configuration for delivery of the apparatus to a location in a patient's body. The seal portion can have a larger outermost diameter in the neutral configuration than in the extended configuration.

A method for maintaining the alignment of the edges of a trocar defect by inserting into a defect a device for compressing the tissue such that part of the device is above while the other is below the defect, then pulling back on the device so that the part below the defect is up against the defect, then while holding the device below the defect in place, push down on the part above the wound so that it compresses the tissue. Finally, release the device from the insertion tool.

An electrosurgical electrospinning device is presented including a reservoir having a polymer solution disposed therein, the reservoir cooperating with a dispensing apparatus configured to dispense the polymer solution from the reservoir. The electrosurgical electrospinning device further includes a plurality of nozzles connected to the reservoir, each nozzle of the plurality of nozzles including a plurality of needles and a blow-spraying mechanism for blowing gas around each nozzle of the plurality of nozzles when the polymer solution is dispensed from the plurality of needles. The gas from the blow-spraying mechanism and the polymer solution from the plurality of needles are coaxially applied directly onto tissue at voltages of less than or equal to 3 kV.

A treatment system includes an insert that is resiliently deflectable. The tip portion of the insert can be configured to be coupled to the trailing portion of an implant. A guide tube having an internal lumen is configured to permit passage of the tip portion and the body portion of the insert through a guide tube. The guide tube can have a length that is less than that of the insert. Treatment systems include a plurality of inserts, each insert differing from in at least one of length, diameter, and curvature. Treating a patient can include sizing a fistula using an insert.

A reduced-pressure, wound closure system is presented that generates a closing force on a surface wound and optionally provides reduced pressure to a body cavity or tissue site. The sealed contracting member, when placed under reduced pressure, generates the closing force. One illustrative system includes a first attachment member and a second attachment member, a sealed contracting member coupled to the first attachment member and the second attachment member, and wherein the closing force is generated between the first attachment member and the second attachment member when reduced pressure is supplied to the sealed contracting member. Other systems and methods are presented.

A prosthesis and a method of plugging or covering a trocar tract with the prosthesis is disclosed. The prosthesis includes a tubular body having a proximal end and a distal end, a respective opening at each end, and a channel extending between the proximal end of the tubular body and the distal end of the tubular body. The prosthesis is removably mounted along a trocar. The trocar is removable from the prosthesis such that the prosthesis is left at the trocar tract when the trocar is removed from the tract. The prosthesis includes a delivery configuration and a deployed configuration. In the deployed configuration, the opening at the distal end of the tubular body is smaller than the opening at the proximal end of the tubular body.

Described herein is a medical device for treating a target site, the medical device including, a proximal end including a disc and a distal end including a lobe. The disc and the lobe are connected by a connecting member. The lobe includes a proximal portion defining a proximal surface of the lobe, a distal portion defining a distal surface of the lobe, and a middle portion connecting and extending between the proximal portion and the distal portion. A first transition between the proximal portion and the middle portion is curved, and a second transition between the middle portion and the distal portion is curved. The medical device also includes a plurality of stabilizing wires coupled to the lobe at a radially outer surface of the middle portion, each stabilizing wire including a hook portion extending radially outward from the at least one lobe.

A method of manufacturing a reduced-pressure abdominal treatment system for treating an open abdominal cavity is provided. In some embodiments, the reduced-pressure abdominal treatment system has an open-cavity treatment device for providing reduced-pressure treatment to an abdominal cavity; a deep-tissue closure device for applying a closing force on a deep-tissue wound; and a surface-wound closure subsystem for providing a closing force on a surface wound. The method of manufacturing may also include providing a reduced-pressure supply subsystem. A method of treatment using a reduced-pressure abdominal treatment system is also disclosed.