A method of obtaining a compound may include adding a substrate to a medium in a reactor, and reacting the substrate in the reactor to form the compound. A first stream is separated from the reaction liquid through a first membrane. A second stream is separated from the reaction liquid through a second membrane. The first membrane is a filtration membrane and the second membrane is configured for liquid-gas or liquid-liquid extraction The first membrane and the second membrane are at least partially immersed in the medium and are moved relative to the reactor during the separation steps.

Methods and systems to control flexible gas fermentation platforms for improved conversion of CO.sub.2 into products is developed and particularly relates to a control process and system to control a ratio of feedstock gases and maximize the concentration of inert components in a bioreactor tail gas stream and or bioreactor headspace. Improved carbon utilization results though providing the most beneficial ratio of substrates to the bioreactor of the fermentation process.

Methods and systems to control flexible gas fermentation platforms for improved conversion of CO.sub.2 into products is developed and particularly relates to a control process and system to control a ratio of feedstock gases and maximize the concentration of inert components in a bioreactor tail gas stream and or bioreactor headspace. Improved carbon utilization results though providing the most beneficial ratio of substrates to the bioreactor of the fermentation process.

The disclosure provides methods to improve the economics of the gas fermentation process. A fermentation process is integrated with an industrial or syngas process and an reverse water gas shift process. An intermittent supply of reverse water gas shift process feedstock from the reverse water gas shift process is provided to the bioreactor for fermentation. The reverse water gas shift process feedstock may supplement or partially displace the C1 feedstock from the industrial or syngas process. Whether the reverse water gas shift process feedstock supplements or displaces the C1 feedstock may be based upon a function of the cost per unit of the C1 feedstock, the cost per unit of the reverse water gas shift process feedstock, and the value per unit of the fermentation product, or may depend upon the target gas ratio of the feedstock to the gas fermentation process.

The disclosure provides methods to improve the economics of the gas fermentation process. A fermentation process is integrated with an industrial or syngas process and an reverse water gas shift process. An intermittent supply of reverse water gas shift process feedstock from the reverse water gas shift process is provided to the bioreactor for fermentation. The reverse water gas shift process feedstock may supplement or partially displace the C1 feedstock from the industrial or syngas process. Whether the reverse water gas shift process feedstock supplements or displaces the C1 feedstock may be based upon a function of the cost per unit of the C1 feedstock, the cost per unit of the reverse water gas shift process feedstock, and the value per unit of the fermentation product, or may depend upon the target gas ratio of the feedstock to the gas fermentation process.

An integrated process and system for the production of at least one gas fermentation product from a gaseous stream has been developed. The disclosure provides improved carbon utilization through both the recycle of a bioreactor tail gas via various different flow schemes and the employment of a CO.sub.2 to CO conversion system such as a reverse water gas shift unit. Recycling of the bioreactor tail gas and employment of a CO.sub.2 to CO conversion process provides for favourable H.sub.2:CO molar ratios of the feed to the gas fermentation bioreactor(s) for enhanced production of fermentation products. Bypass embodiments provide for optimal sizing of the reverse water gas shift unit to minimize cost.

An integrated process and system for the production of at least one gas fermentation product from a gaseous stream has been developed. The disclosure provides improved carbon utilization through both the recycle of a bioreactor tail gas via various different flow schemes and the employment of a CO.sub.2 to CO conversion system such as a reverse water gas shift unit. Recycling of the bioreactor tail gas and employment of a CO.sub.2 to CO conversion process provides for favourable H.sub.2:CO molar ratios of the feed to the gas fermentation bioreactor(s) for enhanced production of fermentation products. Bypass embodiments provide for optimal sizing of the reverse water gas shift unit to minimize cost.

This disclosure is related to a process and apparatus for producing and recovering at least one fermentation product from a fermentation process using a C1-containing gas passed to a fermentation bioreactor, that produces a fermentation broth comprising at least one of a first product stream comprising ethanol and water or a second product stream comprising ethanol, acetone, and water or a third product stream comprising ethanol, acetone, isopropanol, and water. The product is recovered by using a shared product recovery system. Particularly, the shared product recovery system selectively recovers at least one enriched product stream selected from an enriched ethanol stream, an enriched acetone stream, an enriched isopropanol stream or combinations thereof. The shared product recovery system includes at least one of a vacuum distillation unit, a rectification unit, an acetone removal unit, a drying unit, an ethanol-acetone separation unit, an extractive distillation unit or combinations thereof.

A system for the production of high value chemicals includes (a) an input selected from the group consisting of ethylene glycol, glycerol, ethanol methanol or a combination thereof. In addition, the system includes (b) an oxidation biocatalyst including an alcohol oxidase, a copper radical oxidase, a glycerol oxidase, an alditol oxidase or a combination thereof. Further, the system includes (c) an oxidized intermediate. The system also includes (d) a finishing catalyst including a supported metal catalyst, a carboligating catalyst, an amine oxidase, a glyoxalase, an acid catalyst, a base catalyst, an isomerization catalyst or a combination thereof. Still further, the system includes (e) an output.

A system for the production of high value chemicals includes (a) an input selected from the group consisting of ethylene glycol, glycerol, ethanol methanol or a combination thereof. In addition, the system includes (b) an oxidation biocatalyst including an alcohol oxidase, a copper radical oxidase, a glycerol oxidase, an alditol oxidase or a combination thereof. Further, the system includes (c) an oxidized intermediate. The system also includes (d) a finishing catalyst including a supported metal catalyst, a carboligating catalyst, an amine oxidase, a glyoxalase, an acid catalyst, a base catalyst, an isomerization catalyst or a combination thereof. Still further, the system includes (e) an output.