A surgical instrument includes a first jaw defining a channel, a second jaw including an anvil plate, a staple cartridge, and a drive beam. The staple cartridge is received in the channel and includes a sled, a knife blade, a plurality of staple pushers, and a plurality of staples. The sled is movable into engagement with the staple pushers to eject the staples from the staple cartridge. The knife blade is secured to the sled and is movable between raised and lowered positions.

A rotational atherectomy device includes a drive shaft, a cutter mechanism coupled to the drive shaft and configured to cut occlusive material from a lesion, and a multi-stage macerator coupled to the drive shaft and configured to macerate cut occlusive material into a fine slurry. Successive stages of the multi-stage macerator macerate the cut occlusive material into successively smaller particles, which are moved proximally through a lumen of a sheath of the device that surrounds the drive shaft proximal to the macerator. The device may include a movable cutter mechanism guard that is passively rotatable between a first position in which it covers the cutter mechanism and a second position in which it exposes the cutter mechanism. One or more features of the device may limit a depth to which the cutter mechanism is able to cut the occlusive material to reduce a likelihood of undesirable tissue dissection.

An aspiration system exhibits an accelerated drop in negative pressure at the distal end of an aspiration catheter from the time of opening a valve. The system includes an aspiration pump in communication with a first chamber, and an aspiration catheter configured for placement into fluid communication with the first chamber by way of an elongate aspiration tube. A second chamber is provided between the aspiration tube and the catheter, and a valve is provided between the second chamber and the aspiration catheter. Upon opening of the valve with negative pressure at equilibrium in the first and second chambers, resistance to fluid flow between the second chamber and the distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

A surgical instrument for use with a robotic system that has a control unit and a shaft portion that includes an electrically conductive elongated member that is attached to a portion of the robotic system. The elongated member is configured to transmit control motions from the robotic system to an end effector.

A method for conducting intrabody surgery by means of a surgical device having a cutting arrangement actuated by a driveshaft and rotationally supported by the guide wire. A receiving cannel extends through the cutting arrangement and movably receives the guidewire. A plurality of sensors is provided within the cutting arrangement to emit signals capable of changing parameters depending on the composition of the occlusion, so as to allow the control unit to generate signals controlling operation of the cutting arrangement. The method includes the steps of detecting parameters within the intrabody area by the sensors to controlling operation of the cutting arrangement with the power and control unit.

A basket actuator includes a base including a base body and a base guide installed in the base body, a slider including a slider body configured to slide along the base guide, and a first slider arm and a second slider arm formed to protrude from the slider body and facing each other, a roller including a roller body rotatably disposed between the first slider arm and the second slider arm and a plurality of roller blades formed to protrude outwardly from the roller body, a wire guide connected to a front end portion of the base body, a wire disposed inside the wire guide and having a first end fixed to the roller, and a basket connected to a second end of the wire. The second slider arm is located rearward in comparison to the first slider arm.

A basket actuator includes a base including a base body and a base guide installed in the base body, a slider including a slider body configured to slide along the base guide, and a first slider arm and a second slider arm formed to protrude from the slider body and facing each other, a roller including a roller body rotatably disposed between the first slider arm and the second slider arm and a plurality of roller blades formed to protrude outwardly from the roller body, a wire guide connected to a front end portion of the base body, a wire disposed inside the wire guide and having a first end fixed to the roller, and a basket connected to a second end of the wire. The second slider arm is located rearward in comparison to the first slider arm.

A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes inserting an intramural crossing device into the vascular lumen, positioning at least the distal tip of the crossing device in the vascular wall, advancing an orienting device over the crossing device such that an orienting element of the orienting device resides in the vascular wall, inserting a reentry device, and re-entering the true vascular lumen.

A system for accessing a central pulmonary artery includes an elongate, flexible tubular catheter, having a proximal end, a distal end and a catheter hub on the proximal end. An elongate, flexible rail has a proximal end, a distal end and a rail hub on the proximal end. The rail has a distal advance segment which extends at least about 10 cm beyond the distal end of the catheter when the catheter hub is adjacent the rail hub.