The present invention relates to bacteria and metabolites thereof that are capable of binding to vaginal cells and producing hydrogen peroxide, their use in probiotic compositions and food products and methods for their selection. The invention also relates to the use of said bacteria, metabolites and probiotic compositions for the prevention and/or treatment of urogenital disorders.

Provided is a Lactobacillus casei producing short-chain fatty acids in a high yield, a culture method therefor and an application thereof. Lactobacillus casei LC89 capable of producing short-chain fatty acids in a high yield is preserved in the China General Microbiological Culture Collection Center on 5 Mar. 2018, with the accession number of CGMCC NO. 15409 and a classification name of Lactobacillus casei. Provided is a Lactobacillus casei producing short-chain fatty acids in a high yield, which is superior to the commercial strain, Lactobacillus rhamnosus GG (LGG). Also provided are a cultivation method therefor and an application thereof in the treatment of host inflammatory bowel diseases to achieve functions of supplementing probiotics to regulate the intestinal tract and alleviating host inflammatory bowel diseases.

A method for preventing or treating oral cancer includes administering a composition comprising Lactobacillus paracasei or a supernatant of the heat-killed Lactobacillus paracasei. A composition that contains an active ingredient with anti-oral cancer effect. The active ingredient is Lactobacillus paracasei GMNL-346 or the supernatant of the heat-killed GMNL-346. The deposition number of the Lactobacillus paracasei GMNL-346 is BCRC 910953 or CCTCC M 2019983.

A microbial composition for improving the conditions in animal farms comprising: a slow-releasing carrier base having a first predetermined percentage by weight (w/w %); and a mixture of microorganisms identified in a 16S rRNA gene sequence so that the composition is capable of denitrification, feces decomposition, and hydrogen sulfide (H.sub.2S) oxidation.