A liquid applicator (1) for holding and discharging a curable liquid composition, comprises a receiver body (2) for holding a curable liquid composition, a discharge tip (20;30;40) having a longitudinal axis and further having a distal end remote from the receiver body (2) from which the liquid composition is discharged, and a discharge mechanism (5) for transferring liquid composition held by the applicator (1) to the tip (20;30;40) for discharge of the composition. The tip (20;30;40) comprises an outlet section (21d;31d;44d) having at least one groove formation (26;38;48) extending along the tip (20;30;40) to the distal end thereof. The applicator may be a surgical adhesive applicator.

The invention provides intravascular devices for treating certain medical conditions such as edema without causing thrombosis. The intravascular devices of the disclosure include non-thrombogenic surfaces that improve blood compatibility by reducing device-related thrombus formation and inflammatory reactions. The non-thrombogenic surfaces may include surface topographies (e.g., surface roughness) and modified chemistries (e.g., coatings and/or treatments), which prevent thrombosis by reducing local shear forces and inhibiting adhesion of blood clotting factors.

The invention provides intravascular devices for treating certain medical conditions such as edema without causing thrombosis. The intravascular devices of the disclosure include non-thrombogenic surfaces that improve blood compatibility by reducing device-related thrombus formation and inflammatory reactions. The non-thrombogenic surfaces may include surface topographies (e.g., surface roughness) and modified chemistries (e.g., coatings and/or treatments), which prevent thrombosis by reducing local shear forces and inhibiting adhesion of blood clotting factors.

A robotic surgical system includes a surgical instrument and a robotic surgical assembly. The robotic surgical assembly defines an instrument opening and includes a floating plate and a drive assembly. The floating plate is movable between an extended position and a compressed position. The surgical instrument is laterally receivable in the instrument opening of the robotic surgical assembly while the floating plate is disposed in the compressed position. The floating plate is movable to the extended position to couple the surgical instrument to the robotic surgical assembly while the surgical instrument is received in the instrument opening of the robotic surgical assembly.

Provided are an end tool of a surgical instrument and a method of manufacturing the same, and more particularly, an end tool of a surgical instrument that may be manually operated to be used in laparoscopic surgery or other various surgery and a method of manufacturing the end tool, wherein a load applied to a pin (rotary shaft) and the pulley is appropriately distributed such that the pulley may be sufficiently rotated and at the same time, an overall durability may be improved.

Disclosed is a system (100) for inserting an adapter. The system can include a docking station (104) and an adapter inserter (102). The docking station can include a handle block (108), a push assembly, and a linkage (320) connecting knob push handle (120) to an engagement tube pull block (324). The engagement tube pull block (324) can extend from the linkage through a portion of the handle bock. The adapter inserter (102) can include a handle body (112), an engagement assembly (116), and a clamp (412). The handle body can be sized to fit in a first recess (110) defined by the handle block body. The engagement assembly (116) can extend from a second end of the handle body (112) and can be configured to engage the adapter (132) at a tip of the engagement assembly. The clamp (412) can be located within and proximate a second end of the handle body so as to engage a portion of the engagement assembly.

An ultrasonic device may include an electromechanical ultrasonic system defined by a predetermined resonant frequency, the electromechanical ultrasonic system including an ultrasonic transducer coupled to an ultrasonic blade. A method of controlling energy delivered to the ultrasonic device may include determining an impedance of the ultrasonic transducer during a transection process, analyzing the impedance of the ultrasonic transducer, profiling the ultrasonic blade based on the impedance, and adjusting a power delivered to the transducer during the transection process based on the profile of the blade. The method may further include pulsing, the power delivered to the ultrasonic transducer, determining changes in tissue characteristics of tissue located in an end effector, wherein the changes in tissue characteristics is determined between pulses, and adjusting power delivered to the ultrasonic transducer based on the tissue changes throughout the transection. An ultrasonic instrument may include components configured to effect the method.

Described herein are systems, devices and methods that enable dynamic modification of the physicochemical properties of a hydrogel during its in vivo formation and delivery by a catheter. In some example embodiments, an extended endoluminal hydrogel delivery device is employed for delivering a hydrogel within given body cavity, such as within the lumen of a blood vessels. In some example embodiments, a hydrogel precursor, as a non-viscous liquid, is injected through an intravascular catheter and crosslinking of the hydrogel precursor is initiated within a distal region of the catheter. The crosslinking process is controlled, by a control means associated with a distal region of the catheter, to control or modify one or more properties of the hydrogel. The properties may be controlled such that a hydrogel is suitable to embolize the specific target or deliver drugs or other materials beneficial to the site.

A dilator tip may include an elongated tubular member defined by a circumferential wall and having a distal tip region and a proximal end, and a plurality of ribs extending longitudinally between the distal tip region and the proximal end. The plurality of ribs may extend radially outward from the elongated tubular member, and the plurality of ribs may be spaced apart circumferentially.

An aspiration catheter for removing clot from a blood vessel includes a catheter body having a scaffold extending distally from a distal end of the body. An aspiration lumen runs from the distal end to a proximal end of the body, and a central clot-receiving passage in the scaffold is contiguous with the aspiration lumen of the catheter body. A vacuum-resistant membrane covers the scaffold and establishes a clot aspiration path from a distal end of the scaffold to a proximal end of the aspiration lumen, in the catheter body so that applying a vacuum to the proximal end of the aspiration lumen can draw clot into the central clot-receiving passage. The scaffold may have a comical configuration, a cylindrical configuration, or a combination thereof, and at least a distal portion of the scaffold is radially expandable from a delivery configuration to an extraction configuration.