A staple cartridge comprising a tissue thickness compensator is disclosed. The tissue thickness compensator comprises an uncompressed height, a compressed height, an outer encasement, and tubular structures aligned along the longitudinal axis. The tubular structures are configured to collapse when pressure is applied to the tissue thickness compensator by tissue during the firing motion.

A magnetic suture has a ferrule with a tapered region in which a knotted suture is provided and secured with an adhesive, and a straight region in which a magnet is provided. The magnetic suture can be manufactured and assembled by knotting a suture, threading it through the tapered portion, and applying adhesive. The structure and method provide a magnetic suture provide increased manufacturing tolerances and decreased failure rates, thereby reducing waste of components and time while increasing the manufacturing/assembly speed and reliability of magnetic suture assembly.

A wire stabilization device and method for stabilizing a localization wire during a tissue diagnostic procedure are disclosed. The wire stabilization device includes a device body and a device base. The device body is joined to the device base. The device body includes a base portion, a cover portion, a cover hinge, and a gripping feature. The cover hinge connects the base portion to the cover portion and allows the cover portion to rotate between open and closed positions. The gripping feature holds the localization wire between the base portion and the cover portion. The device base attaches to a patient's skin to stabilize the device body while the localization wire is held between the base portion and the cover portion.

A medical device for at least partially covering and applying force on tissue includes a body having a spanning structure and struts respectively connected to lateral portions of the spanning structure. Inner ends of the struts extend into an area over which the medial portion of the spanning structure extends. The medical device is reconfigurable between extended and retracted configurations. The inner ends of the struts are closer to one another in the retracted configuration than in the extended configuration. The inner ends of the struts are closer to the medial portion of the spanning structure in the retracted configuration than in the extended configuration. Each strut includes an engagement zone configured to engage and apply force on the tissue, at least while the medical device is in the retracted configuration. A web can be connected to the struts and span between the inner ends of the struts.

The present invention introduces a material, i.e. a device, which is insertable into a vein of a outer parts of a sheath, two-sidedly adhesive tubular material with a supporting material and protrusions, either a balong or an inner protective film, and a control cable for the insertion and extraction of the device along the vein. The supporting material may be compressed initially, and after removal of the outer part of the sheath, the supporting material with protrusions will expand towards the vein walls. After removal of the inner part of the sheath and the control cable, the treated vein area can be manually pressed on top of the skin, thus closing the vein through inner and outer adherence of the material. The protrusions may have a barbed shape.

An adaptable suction tubing apparatus for a surgical retractor is disclosed. The suction tubing apparatus comprises a suction tip connector, an extruded rectangular tubing and an end suction connector. All components also have side protrusions or bumps for nesting into top channels over the top surface of a surgical retractor. These side protrusions provides snug fit within a surgical retractor. Optionally the tubing can have double sided adhesive tape for placement over the top surface of a standard surgical retractor. The suction tubing apparatus is designed for one time use and has low profile and conformed to the contour of any retractors perfectly.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

Disclosed is an umbilical orthesis plug for an infant, child or toddler. The plug comprises a flange and a body, wherein the body is connected to the flange and wherein the body tapers in width from the flange to the end of the plug. Methods for using the plug and kits comprising the plug are also disclosed.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

A sealant for sealing a puncture through tissue includes a first section, e.g., formed from freeze-dried hydrogel, and a second section extending from the distal end. The second section may be formed from PEG-precursors including PEG-ester and PEG-amine, e.g., in an equivalent ratio of active group sites of PEG-ester/PEG-amine greater than one-to-one, e.g., such that excess esters may provide faster activation upon contact with physiological fluids and enhance adhesion of the sealant within a puncture. At least some of the precursors remain in an unreactive state until exposed to an aqueous physiological environment, e.g., within a puncture, whereupon the precursors undergo in-situ cross-linking to provide adhesion to tissue adjacent the puncture. For example, the PEG-amine precursors may include the free amine form and the salt form. The free amine form at least partially cross-links with the PEG-ester and the salt form remains in the unreactive state in the sealant before introduction into the puncture.