A minimally invasive surgical suture end locking device includes a hooking assembly, a clamping structure, a power rod and an external conduit. The hooking assembly includes an annular structure enclosed by a flexible material and a force application end, the clamping structure is configured to press the locking pin, the power rod is configured to press the clamping structure by linear motion, and the external conduit is provided with a through hole, the through hole being provided on the side of a position where the clamping structure and the power rod contact each other for a portion of the suture passing through the through area to be led out. There is provided in the present invention a device that allows to tighten and lock the suture directly at the end proximal to the position where the suture is led out from the human tissue.

Devices, systems and methods for fixating soft tissue to bone. In one embodiment, a repair device system for fixating soft tissue to bone includes a carrier member, multiple anchors, and a bone anchor. The carrier member includes multiple pad portions and a bone coupling portion. Each of the pad portions are aligned with an adjacent pad portion. The pad portions are configured to be positioned over a side of the soft tissue and the bone coupling portion is coupled to the multiple pad portions. Each anchor is sized and configured to extend through the at least one opening defined in one of the multiple pad portions and through the soft tissue. The bone anchor is configured to be coupled to the bone coupling portion and configured to be secured to the bone.

Embodiments of knotless button-suture assemblies for orthopedic stabilization are disclosed. The button-suture assembly includes a button having a first opening, a second opening and a center opening. The assembly further includes a tensioning member having two tensioning member ends exiting from the first opening and the second opening of the button and disposed in the proximal direction. The assembly further includes a locking pin mated with the button through the center opening of the button in such a manner that allows a proximal movement of the tensioning member when a pulling force is applied to the tensioning member ends towards a proximal direction and prevents a distal move-ment of the tensioning member when the pulling force applied to the loose ends of the tensioning member ceases to exist.

A device for use in bariatric surgery includes a flexible hollow tube extending from a proximal end to a distal end and defines a channel therebetween. A series of openings is defined in a distal portion of the tube allowing for fixation of tissue using suction. A flexible member has an initial position disposed alongside the tube and is deployable to a subsequent position in which the flexible member engages a greater curvature of a stomach. The flexible member is configured to be deployable to automatically assume a shape of a greater curvature of a stomach. The flexible member includes a bulging region and a tapering region when deployed. The flexible member is releasably attached to the distal end of the tube.

Methods and devices for transvascular prosthetic chordae tendinae implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Medical devices for cinch and cutting one or more suture, and methods for making and using such devices are disclosed. An example medical device may include a coupler, a sleeve releasably coupled to the coupler, a cutter slidably disposed within the sleeve, and a suture cinching member movable into and out of the sleeve. A wire may extend through and be longitudinally movable within the coupler to move the suture cinching member and cutter.

An implant assembly for use in tissue repairs includes a fixation device and a flexible elongate implant. The fixation device has a body with a first surface adapted to face towards a bone and a second surface adapted to face away from the bone. Apertures extend through the fixation device body from the first surface to the second surface and serve to attach one end of the flexible elongate implant loop. The flexible elongate implant has a multifilament structure comprising filaments which are of a metallic or non-metallic material. The implant is coupled to the fixation device by passing through the apertures, and has a loop having a first end that is secured to the fixation device and a second end which can be releasably coupled to the fixation device following passage through or around a bone, for securing the implant assembly relative to the bone.

A method of closing a patent foramen ovale (PFO) including a septum primum and septum secundum is implemented using a suture device including an operational shaft housing an anchor assembly, a needle assembly, and a suture. The method includes advancing an end of the operational shaft to a proximal side of the PFO, positioning a distal portion of the end of the operational shaft on a distal side of the PFO, and actuating the anchor assembly to deploy the anchor assembly on the distal side of the PFO. The method also includes actuating the needle assembly on the proximal side of the PFO to deploy the needle assembly through the PFO and the anchor assembly, thereby deploying the suture through the PFO. The method further includes retracting the anchor assembly into the operational shaft, and withdrawing the distal portion of the operational shaft from the PFO, leaving the deployed suture.

Disclosed herein are suture clip delivery devices that can be loaded with several flat, disk-shaped suture clips and can deploy the suture clips one after another onto respective sutures without reloading the device with additional suture clips. An exemplary device includes a handle portion with an actuation mechanism that is coupled to a shaft portion that holds and deploys the suture clips. The shaft portion includes a mandrel on which the suture clips are mounted and a retainer that restricts the suture clips from moving proximally when the actuation mechanism pulls the mandrel proximally, which causes a distal-most suture clip to slide off the mandrel and be deployed onto one or more suture. The mandrel and remaining suture clips can then move distally to prepare to deploy the next suture clip.

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.