A medical device and methods for hemostasis in a living body are disclosed. The medical device including a base configured to arranged on an upper surface of the tissue in the living body; a plurality of levers, each of the plurality of levers having a needle arranged on a lower surface thereof and configured to puncture the tissue in the living body, and wherein the plurality of lever are configured to be received with a slot or track of the base; and at least one tie, the at least one tie configured to hold together the plurality levers and needles upon compressing the tissue in the living body upon moving the plurality of levers inward in the slot or track of the base.

A combined magnetic and bioabsorbable device for ventral hernia closure and/or tension distribution for maintenance of tissue apposition for healing, while avoiding a long-term footprint of foreign material and precluding materials spanning the interior layer of the abdominal closure where risk to visceral structures exists.

A tissue traction device includes a first needle connected to a distal end of a first thread; a second needle connected to a distal end of a second thread; an elongated main body connected to the first thread and extending between the first thread and the second thread, the main body being elastically deformable; a tube disposed at a proximal end of the main body; and a traction member having a distal end connected to a distal end portion of the main body, the traction member extending from the distal end portion of the main body toward a distal end of the tube.

Disclosed is a medical device for use in surgery including at least one structured substrate including a plurality of structures, at least a portion of the plurality of structures being a plurality of ridges having each a length that is at least 5 times greater than their width. The ridges have at least two different cross-sections and have swellable properties, for example in the presence of water. The medical device includes at least a second substrate, including a second plurality of structures, the first and second plurality of structures being arranged to interlock when the first substrate is pressed against the second substrate in presence of water.

Disclosed is a two-component medical device useful for closing a wound or incision. The two-component medical device includes first and second adhesive-backed anchoring members having wound edges. A first and a second release liner protect the first adhesive-backed surface of the first adhesive-backed anchoring member. A first and a second release liner also protects the second adhesive-backed anchoring member. Each of the first and second release liners include a tab portion for removal of the associated first or second release liner.

A surgical clamp for aligning the margins of incised or wounded tissue has jaws with parallel clamping faces, and a handle for manipulating the clamp to align the margins of the tissue. The jaws are in a normally closed position, however they can be opened by compressing the handle to open the jaws. Prongs project from the inferior surface of the jaws. The clamp is positioned in a desired position over the margins of a wound to be closed, the prongs engage the margins of the wound to be aligned, and the jaws are closed by releasing compressive force on the handle. As the jaws close the prongs help move the tissue into alignment. Suture guide slots through the jaws assist in the placement of precisely placed sutures across the incision. The disclosed surgical clamp is particularly suited for selectively closing and reopening surgical incisions, such as a sclerotomy incision in the eye. Methods are disclosed for using the clamp during intraocular and other surgical or minimally invasive procedures. In one example the clamp is used during implantation into the retina of a scaffold on which choroid and retinal pigment epithelium cells and retina grow in a three-dimensional matrix that mimics the native structure of the retina.

Devices for approximating multiple tissue edges internal to a body are disclosed.

A tissue approximation device for wound closure having a first arm having a proximal end and a distal end, a second arm having a proximal end and a distal end, the second arm connected to the first arm. A first rake member is connected to the distal end of the first arm and has a first plurality of tissue engaging members extending therefrom to engage tissue. A second rake member is attached to the distal end of the second arm, the second rake member having a second plurality of tissue engaging members extending therefrom to engage tissue. A transverse bar can extend through the first and second rake members such that the first and second rake members movable along the transverse bar. Systems and methods for wound closure are also disclosed.

An volume filling device for treatment of obesity is placed outside the stomach wall of the patient to reduce the inner volume of the stomach, thereby affecting the patient's appetite. By providing the volume filling device outside the stomach wall, contact with stomach acids is avoided, thereby increasing the life of the device.

Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.