Gastro-intestinal-tract endoluminal apparatus (10) for deploying markers (42, 44, 46) into a gastro-intestinal tract of a patient, the apparatus being retrievably insertable into the gastro-intestinal tract, comprising: a flexible tube (12) introducible into the gastro-intestinal tract of a patient, the tube having a stationary end (12d) and a mobile lumen (14), the tube being extendable within the tract by inflating an inflatable region (16) of the tube around the lumen, the inflation causing distal-most invaginated material (12c) to evert outwardly such that the everted material extends a deployed length of the tube distally along a path of the gastro-intestinal tract, invaginated material (12b) of the lumen being drawn distally within the deployed tube to feed the distal extension.

An everter device to facilitate preparation of ends of arterial segments for end-to-end microvascular anastomosis. The device includes structure that provides sufficient support to prevent unwanted buckling of arterial tissue. The everter device offsets the tendency of the arterial tissue wall to recover its natural shape and fall off securement posts or pins of a coupler ring. The structure may be in the form of an intraluminal catheter balloon. Alternately, the structure may be in the form of a plunger. Alternately, the structure may be in the form of a radially expanding member provided on a shaft. The device further has a contoured surface on an everter end to evert a free end of arterial tissue over a coupler ring, and to cause the posts or pins of the coupler ring to pierce through the everted arterial tissue. The everter end is provided with one or more openings therein, such as a circumferential slot, to receive the posts or pins of the coupler ring.

A vascular anastomotic coupling device includes, for each of two vessels prepared for anastomosis, an inner ring sized to slide over an outer diameter of one of the two vessels. An outer ring is configured to trap an everted portion of the one of the two vessels between itself and the inner ring. Interface features on the inner ring and outer ring are configured to trap and hold the everted portion of the one of the two vessels between them and fix a position of the inner ring and outer ring with respect to each other. A connection interface on the outer ring is configured, when mounted on the one of the two vessels, to join with the outer ring of the other of the two vessels to join the two vessels and complete anastomosis of the two vessels.

A surgical apparatus used in an ostomy procedure includes an introducer configured for atraumatic insertion in a tissue opening and a dilator. The dilator includes an elongate body and an extension movably coupled to the elongate body. A distal portion of the elongate body is disposed within and axially movable relative to the introducer between first and second positions. The extension is configured to move from a retracted state to an expanded state in response to movement of the dilator relative to the introducer from the first position to the second position. In the retracted state, the extension is disposed within the introducer, and in the expanded state the extension projects laterally outward from the distal portion of the elongate body.

Various embodiments of the present disclosure include an apparatus comprising a clip which includes a first side including a first ring configured to pass over an end of a first vessel, the first ring configured to engage the first side with the first vessel, and a second side coupled to the first side, the second side including a second ring configured to pass over an end of a second vessel, the second ring being configured to engage the second side with the second vessel. The first and second sides, when in a closed position, are configured to maintain the first and second vessels in substantially end-to-end contact.

A sleeve for enforcing the end of a hollow organ so that it can be connected with a further end of a hollow organ, the sleeve comprising a cylindrical shape and being configured to be pushed over the end of the hollow organ and for turning-over the end of the hollow organ projecting from the sleeve around an end of the sleeve, wherein the sleeve has an adjustable diameter.

An anastomosis set for anastomosing a first end to be anastomosed with a second end to be anastomosed, such anastomosis set comprising: a first manipulator, with a first telescoping part at a distal end thereof, the first telescoping part is used for telescoping toward the first end to be anastomosed; a second manipulator, with a second telescoping part at a distal end thereof, the second telescoping part is used for telescoping toward the second end to be anastomosed; and an anastomosis mechanism for anastomosing the first end to be anastomosed with the second end to be anastomosed; the first manipulator including a first exit part through which the first manipulator will be removed from the first end to be anastomosed after anastomosing; the second manipulator has a second exit part, through which the second manipulator will be removed from the second end to be anastomosed after anastomosing.

Devices, systems, and methods for inverting and closing the left atrial appendage. In at least one embodiment of a method for closing a left atrial appendage of the present disclosure, the method comprises the steps of inverting a distal portion of a left atrial appendage, and constraining the inverted distal portion of the left atrial appendage using a device configured to fit within an interior of the left atrial appendage.

An anastomosis device includes a stapler and an anvil. The stapler includes a clamp head with opposing first and second clamp jaws and a clamp actuator and clamp lock. Staple magazines are connected to the clamp jaws for retaining a plurality of staples in an array, and drivers are provided for moving the plurality of staples in the array out of the staple magazine. An anvil includes a clamp head with opposing first and second clamp jaws, a clamp actuator and a clamp lock. Anvil portions are connected to the clamp jaws. The stapler detachably engages to the anvil, and aligns the staple magazines with the anvils. The drivers are operated to move the staples from the staple magazines into contact with the anvil portions. A method for performing anastomosis is also disclosed.

Methods, devices, apparatus, assemblies, and kits for performing a vascular anastomosis are disclosed. A device for a vascular anastomosis includes tissue engaging portions that can move between at least two configurations. In some embodiments, the tissue engaging portions move without the aid of moving parts, while in other embodiments the tissue engaging portions extend from one or more movable wings. The tissue engaging portions may be separated by a first distance when in a pre-deployment configuration and by a second distance when in a deployed configuration. A method includes engaging a plurality of tissue engaging members of a coupling device against first end tissue. After selectively engaging the tissue engaging members and first end tissue, the first end tissue is stretched by at least moving the tissue engaging members. The stretched first end tissue is coupled to the second end tissue by mating the coupling device to a mating anastomosis device.