Devices and methods for occluding or promoting fluid flow through openings are disclosed. In one exemplary embodiment an occlusion device is provided having an expandable outer elongate tubular body, a guide member extending from a distal end of the outer body, and a slide tube disposed within the outer body, the proximal portions of the outer body and the slide tube being fixedly mated. The slide tube is configured to slide distally within the outer tubular body when the tubular body is expanded to form wings. A tether can be included as part of the device and it can be used to assist in positioning and locking a location of the device in an opening. Exemplary methods for delivering devices disclosed herein are also provided.

Embodiments of the invention provide systems and methods for using a tissue scaffold to facilitate healing of an anastomosis. One embodiment provides a tissue scaffold for placement at an anastomotic site within a body lumen comprising a radially expandable scaffold structure having lateral and mid portions, at least one retention element coupled to each lateral portion and a barrier layer. The retention element engages a luminal wall when the scaffold structure is expanded to retain the structure and exert a compressive force on the anastomosis. The mid portion has a greater radial stiffness than the lateral portions such that when the structure is expanded, the lateral portions engage tissue prior to the mid portion. The barrier layer is configured to engage a luminal wall when the structure is expanded to provide a fluidic seal at the anastomosis. The barrier layer may also include releasable biological agents to promote anastomotic healing.

A surgical instrument for bonding body tissue includes a shank and first and second tool elements which are movable relative to each other and include a respective electrode. The electrodes define a minimum distance from each other, are opposed to each other and face each other in an approximating position of the tool elements. The first tool element is arranged or formed at the distal end of the shank, so that a mechanical load of anastomoses of body tissue parts produced by current flow is minimized when removing the surgical instrument. The second tool element is adapted to be brought from an operating position, in which it can be brought into the approximating position, into a removing position, in which a peripheral withdrawing line defined by the electrode of the second tool element is shorter than a peripheral approximating line defined by the electrode in the approximating position.

Various embodiments of the present disclosure include an apparatus comprising a clip which includes a first side including a first ring configured to pass over an end of a first vessel, the first ring configured to engage the first side with the first vessel, and a second side coupled to the first side, the second side including a second ring configured to pass over an end of a second vessel, the second ring being configured to engage the second side with the second vessel. The first and second sides, when in a closed position, are configured to maintain the first and second vessels in substantially end-to-end contact.

An ultrasound-detectable marker, ultrasound system, and methods for monitoring vascular flow and patency is disclosed. The ultrasound-detectable marker comprises one or more resorbable polymers, one or more non-resorbable polymers, one or more non-polymeric materials, or any combinations thereof. The ultrasound-detectable marker is adapted for placement underneath, adjacent to, or above one or more vessels at a postoperative site, such as a vascular anastomosis site. Further, the ultrasound imaging system includes certain user guiding software and/or health analysis software for use with the ultrasound-detectable marker.

A vascular graft suitable for implantation, and more particular to a vascular graft having an expandable outflow region for restoring patency of the graft after implantation into a body lumen.

A catheter (1) and vein repair method that enables vein repair surgeries without any bleeding and without hindering blood flow in veins through bypassing the blood flow in the vein to be operated and by preventing any diseases arisen due to stop of blood flow of the organ fed by the associated vein and that sustains blood flow by means of vein bypass in the course of vascular surgeries implemented for surgical processes related to veins in human body and that comprises one balloon (3) on each point close to its both ends, protective layer (4) positioned on the balloons (3); second path (5) enabling deflation inflation of the balloons (3), having monolithic pipe shape adhered to the first path (2) side by side, whose one open end terminates within the balloon (3); check valve apparatus (7) that is monolithic with back end of the second path (5) and provides substances such as air and liquid with the injector for inflation deflation of the balloon (3); protective segment (6) surrounding externally the first path (2) and second path (5), thus preventing their blockage when compressed, that may have various lengths from back end of the balloon (3) to the backside of the catheter (1), that is monolithic along with the first path (2) and the second path (5); cover (8) that prevents the catheter apparatus (1) going out of the vein or its movement, that is located on body side of the catheter apparatus (1), positioned on back of the balloon (3), that can be moved over the catheter apparatus (1) as it is wider than body of the catheter apparatus (1), that has flexible structure having both ends open, that can have the shape of funnel or circle or ellipsis or different shapes; clamping apparatus (9) used to fix the cover on its relevant location; at least one third path (10) in the shape of pipe with both ends open, whose one end is positioned within first path (2), other end is located out of first path (2) and used to draw the liquid or air; connection apparatus (11) that is integrated with outer back end of third path (10) and that enables connection with the external injector and the catheters.

Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.

A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another. Additionally, a method is described for using the device and/or system to bypass the duodenum from digestion.

A system for coupling a first space within a body of a patient with a second space within the body of the patient including a flow connector insertable into the first and second spaces within the body and having a conduit having a wall forming a lumen therein and first and second orifices. A first retention member is engageable with a first portion of the first space within the body and has a first opening, and the flow connector is positioned within the first opening. A second retention member is engageable with the second space within the body, the second retention member has a second opening and the flow connector is positioned within the second opening. The second retention member interlocks with the first retention member.