A medical device may include a first body having a lumen and a central longitudinal axis; a second body positioned at least partially within the lumen of the first body; and an arm assembly. The arm assembly may include a first arm coupled to the first body and extending distal to the first body; and a second arm coupled to the second body and extending distal to the second body. A distal end portion of the first arm may be coupled to a distal end portion of the second arm. Distal movement of the second body may be configured to move the first arm and the second arm radially-outward away from the central longitudinal axis. Proximal movement of the second body, relative to the first body, may be configured to move the first arm and the second arm radially-inward towards the central longitudinal axis.

Mechanical thrombectomy apparatuses including an inverting, rolling conveyor region (“tractor”) at the distal end that are configured to grab and remove thrombus material. In particular, described herein are mechanical thrombectomy apparatuses that are adapted to prevent premature deployment of the tractor, e.g., by including a tractor hold (e.g., a housing, a lock, a clamp, etc.) or the like to secure the outer end of the tractor against and/or relative to the elongate inversion support.

A sheath assembly for use with an endoscope and an endoscope that includes the sheath assembly. The sheath assembly can include an elongate tubular sheath configured to thread onto a shaft of the endoscope. The sheath can include a pliable segment at a distal end of the sheath, and a tensile filament extends along a circumference of the pliable segment. The tensile filament can form a cinching loop at a distal end of the pliable segment. The sheath can be displaceable along the endoscope between a retracted position and an extended position. The pliable segment can extend distally beyond a distal end of the endoscope to form a chamber, and proximal displacement of the tensile filament tightens the cinching loop to convert the chamber from an open configuration to a closed configuration.

A surgical instrument assembly is provided. In some embodiments, an example surgical instrument assembly includes a surgical instrument configured to pass through a guide tube having a proximal end and a distal end. The surgical instrument can include one or more arms configured to extend from the intermediate position, each arm having one or more joints positioned along the arm and an end effector attached at the distal end of each arm. The surgical instrument assembly can include a control assembly positioned at the proximal end and configured to control the movement of the joints and the end effectors.

A surgical instrument includes a housing having a first handle and an elongated shaft extending therefrom. An end effector is disposed at a distal end of the elongated shaft and includes first and second jaw members, the first jaw member including a staple cartridge configured to house a series of staples therein. A second handle is operably coupled to the housing and is selectively moveable relative to the first handle to actuate the first and second jaw members between an open position and a closed position for grasping tissue. A first switch is activatable to supply energy to one of the jaw members. A stapler mode switch is actuatable between an unactuated position wherein movement of the second handle moves the jaws to the second position and an actuated position wherein movement of the second handle moves the jaws to the second position and drives the staples through tissue.

Inverting tube apparatuses and methods of using same for removing large amounts of material from a body lumen. The apparatuses and methods described herein may use a depot for holding, in a compressed configuration, a length of the flexible tube configured to invert over the distal end of an inversion support catheter to capture material within a body lumen. The depot is configured to facilitate the release of the flexible tube with a low release force, and in a manner that prevents snagging or binding of the flexible tube either on the body of the catheter or when rolling and inverting into the inversion support catheter.

Rail tension extraction devices and methods of extracting target(s) inside a patient's body are disclosed. The device includes a base assembly having a handle and an elongate base. The device additionally includes at least one magnet configured to engage a metallic target, and a capture element received in the base assembly and disposed adjacent to the at least one magnet. The capture element is configured to at least partially surround the metallic target engaged by the at least one magnet. The device further includes an outer tube configured to move relative to the elongate base between a locking position in which a distal end of the outer tube is adjacent the capture element and the at least one magnet to secure the metallic target therebetween, and an unlocking position in which the distal end of the outer tube is spaced from the capture element and the at least one magnet.

The invention is a device, system, and method for repairing heart valve function, which may include bisecting native valve leaflets for improved deployment of a prosthetic heart valve in the native valve annulus. The invention may include a catheter having a cutting element shaft with a cutting element configured to puncture a valve leaflet and/or make a controlled cut through the leaflet. The device may have an extendable foot configured to be positioned on an opposite side of the valve leaflet from the cutting element shaft. The device may include magnets to guide the cutting element and/or cutting element shaft in proper alignment with the extendable foot and to hold the elements in place during leaflet bisection.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes inserting an intramural crossing device into the vascular lumen, positioning at least the distal tip of the crossing device in the vascular wall, advancing an orienting device over the crossing device such that an orienting element of the orienting device resides in the vascular wall, inserting a reentry device, and re-entering the true vascular lumen.

Devices, systems, and methods for performing an ophthalmic procedure in an eye are disclosed. The devices include a hand-held portion and a distal, elongate member coupled to the hand-held portion having a lumen operatively coupled to a vacuum source. A drive mechanism operatively coupled to the elongate member is configured to oscillate the elongate member. When in use, the device is configured to aspirate ocular material from the eye through the lumen. The drive mechanism retracts the elongate member with a retraction speed profile and advances the elongate member with an extension speed profile. The retraction speed profile is different from the extension speed profile.