An apparatus for harvesting a subcutaneous blood vessel is disclosed. The apparatus comprises a guidewire with an angled tip, an intra-vascular catheter to receive the guidewire and having a lateral orifice to allow the angled tip thereof to perforate the subcutaneous blood vessel. The apparatus further comprises a flexible pulling device having a pair of circumferential grooves, one adjacent to each end thereof, to allow for securing the subcutaneous blood vessel thereat; and a flexible pushing device having a concave-cup shape at a distal end thereof to facilitate pushing of the subcutaneous blood vessel secured with one of the pair of circumferential grooves of the flexible pulling device. The flexible pulling device and the flexible pushing device are operable in conjunction to cause inversion and eversion and separation from the surrounding tissues of the subcutaneous blood vessel for removal and harvesting thereof.

In some examples, a capture assembly configured to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system, includes a body configured to receive the material of interest. The body can be configured to axially lengthen and shorten.

An endovascular apparatus for crossing through an obstruction in a blood vessel comprises an elongate endovascular element such as a wire. The element has a proximal section, a distal tip section of smaller diameter than the proximal section; and a distally-tapering intermediate section extending between the proximal and distal tip sections. The apparatus comprises an ultrasonic transducer, mechanically coupled to the proximal section of the element for ultrasonically activating the element, hence exciting the distal tip section to facilitate crossing through the obstruction. A catheter surrounds the element, leaving at least part of the distal tip section of the element protruding distally beyond a distal end of the catheter.

The present invention provides a catheter for treating an occlusion in a body lumen. The catheter includes an elongated tube, a first electrode pair and a second electrode pair each configured to generate shock waves. The catheter also includes a flexible polymer enclosure that is fillable with conductive fluid and wrapped circumferentially around at least a portion of the elongated tube such that it surrounds the first and second electrode pairs. The first and second electrode pairs can be arranged relative to one another to promote interference between shock waves generated at the electrode pairs when voltage is delivered across the electrodes of each pair. Electrode pairs can be longitudinally adjacent (spaced a relatively small longitudinal distance apart), longitudinally aligned (at the same longitudinal location), circumferentially offset (offset about the circumference of the catheter), circumferentially aligned (at the same circumferential location), or any combination of any of the above.

A tissue-removing catheter for removing tissue in a body lumen includes an elongate drive member and a tissue-removing element operatively coupled to the distal end portion of the elongate drive member. An inner liner received within the drive coil defines a liner passage sized and shaped to receive a guidewire therein. A distal tip extends distally outward from the tissue-removing element. The distal tip has a proximal end portion disposed within the tissue-removing element and a distal end portion spaced distally from the tissue-removing element. A distal end portion of the inner liner is axially spaced apart from the proximal end portion of the distal tip such that the distal tip is free from direct connection to the inner liner.

A tissue-removing catheter includes a drive assembly. The drive assembly includes a gear rotatable about an axis, a gear extension coupled to the gear and extending axially outward from the gear, and a lock received in and coupled to the gear extension. The gear extension is rotatably driven by the gear, and the lock is rotatably driven by the gear extension. An elongate drive member is received in and coupled to the lock. The drive member is driven by the lock, whereby rotation of the gear imparts rotation to the drive coil.

Self-rolling mechanical apparatuses for removing material from a body lumen include a tractor tube portion that rolls and inverts over itself in a continuous motion, tractor-like, to draw material into the tractor tube, wherein the tractor tube rolls over itself without requiring any additional internal support at the distal-facing region of the tractor tube.

An intravascular thrombus retraction device includes: wires that are compressible into a compact cylindrical form within a catheter and are self-expandable into a wire mesh web with at least some parallel wires forming openings in the wire mesh sufficient to allow fluid passage and small enough to filter particles of at least 0.001 mm, a base of the wire mesh web connected to radial ring-shaped structure supporting and maintaining an opening in the base of the wire mesh and forming a thrombus capture volume, and the radial ring-shaped structure being compressible into the catheter and being self-expandable or expandable by struts when free of compressive forces within the catheter to open up into an open, expanded, radial ring-shaped structure which maintains the opening in the opening in the base of the wire mesh.

A neurovascular access catheter can comprise an elongate, flexible tubular body. The tubular body can comprise a proximal end, a distal end, and a side wall at least partially defining a central lumen. The central lumen can extend axially through the side wall. The tubular body can include a distal microcatheter segment that extends proximally from the distal end. The tubular body can include a proximal shaft that extends distally from the proximal end. The tubular body can include a tapered dilator segment being positioned in between the distal microcatheter segment and the proximal shaft segment.

A clot removal device for removal of an occlusion from a lumen in a patient's body is provided. The clot removal device has a lumen, an elongated member positioned within the lumen and extending axially from a proximal end to a distal end of the lumen, a handle attached to the proximal end of the lumen, a first expandable member positioned along a length of the elongated member, a second expandable member positioned along the length of the elongated member, wherein the second expandable member is distal to the first expandable member relative to the handle. The handle has at least one actuation mechanism and at least one of the following applies: a) the first expandable member is coupled to the at least one actuation mechanism and is configured to be moveable relative to the second expandable member upon manipulation of the at least one actuation mechanism; b) the first expandable member is configured to mechanically expand or contract by manipulating the at least one actuation mechanism; c) the second expandable member is coupled to the at least one actuation mechanism and is configured to be moveable relative to the first expandable member upon manipulation of the at least one actuation mechanism; or d) the second expandable member is configured to mechanically expand or contract by manipulating the at least one actuation mechanism.