A locking catheter system includes a locking mechanism. The locking mechanism includes a lock body having a system lumen extending through the lock body, wherein first and second catheters are received in the system lumen. A system channel extends from the system lumen, and the system channel is configured to receive one or more of the first or second catheters. A locking channel having a lock element extends from the system lumen. The locking channel is configured to receive one or more of the first or second catheters. In an unlocked configuration the first and second catheters are received in the system channel and are movable relative to the lock body. In the locked configuration at least the second catheter is received in the locking channel, the second catheter is statically coupled with the lock body, and the first catheter is movable relative to the lock body.

An intraluminal device and a method of removing a clot from a body lumen with an intraluminal device may be provided. The intraluminal device may include a hollow elongated shaft and a radially-expandable mesh segment situated distal to the elongated shaft. The elongated shaft may be secured relative to a first portion of the mesh segment. The intraluminal device may additionally include a core wire affixed to a second portion of the mesh segment and extending through the elongated shaft. The elongated shaft may be configured to radially expand the mesh segment by axially moving the first portion of the mesh segment relative to the second portion of the mesh segment. In addition, the core wire may be configured to radially expand the mesh segment by axially moving the second portion of the mesh segment relative to the first portion of the mesh segment.

Disclosed herein are systems and methods for visualizing a target anatomy of a patient in preparation of a medical procedure. A system can have transducers defining a grid to collect data about the target anatomy. A user interface (22014) can be disposed on area of the system to visualize the target anatomy. The visualization can include a virtual representation (22016) formed by an imager processor based on the data collected by the transducers. The method can include positioning the visualization device at an orientation where the transducers face the target anatomy. The method can further include adjusting the position of the visualization device to a target anatomy displayed on the virtual representation. The method can further include directing a medical instrument towards a target displayed on the virtual representation.

Systems and methods for creating autologous monocuspid and bicuspid valves can include a catheter having a single expandable element or a double expandable element. Once the leaflets of the valve are created, various techniques can be used to fix the leaflets to the vessel wall or to each other, including clips, tissue anchors, adhesives, and heat.

Disclosed herein are devices and methods for visualizing a target anatomy of a patient in preparation of a medical procedure. The device can include a pad having a conductive material. The pad can include an engaging element that can engage the conductive material to a medical imaging device. The method can include attaching the gel pad to a visualization device. The gel pad can contact the patient. The method can further include viewing the target anatomy using the visualization device. The visualization device can include transducers to collect data on the target anatomy and a user interface to visualize the target anatomy. A medical instrument can be directed into the gel pad and towards the target anatomy. A device can be provided to manage pain during the procedure. The device may include a stimulating element to decrease pain experienced by the patient.

Disclosed herein are systems and methods for visualizing a target anatomical site of a patient using one or more imagers. The method can include placing multiple imagers on multiple locations at an anatomical site. The method can further include generating separate image data sets from the multiple images and combining the image data sets to generate a volumetric imaging data of the anatomical site. The volumetric imaging data can include all anatomical features within the target anatomical site. A visualization system for medical imaging can include transducers on the imagers to visualize the target anatomical site. The system can further include a processor to combine the image data sets to generate the volumetric imaging data set. The system can further include a display device to display the volumetric imaging data set.

Disclosed herein is an apparatus for inserting a needle and a method for cannulation of a blood vessel. The apparatus can include a targeting assembly to identify a target location and an insertion path for the needle. The apparatus can further include a frame and insertion assembly to hold and place the needle. A user interface can be provided to provide feedback to an operator. The apparatus can include an adjustable band that engages a body portion of the patient. The method can include placing and securing the frame to the body portion. The method can further include locating the target location and inserting the needle through a target area.

Systems and methods for removal of clot material from vessel lumens are disclosed. A medical device assembly can include a catheter having a lumen and a distal portion configured to be positioned at or adjacent a treatment site within a vessel. An expandable member has a first portion coupled to the distal portion of the catheter, and a second portion extending away from the catheter distal portion. An elongate shaft extends through the lumen of the catheter, and the second portion of the expandable member is releasably coupled to the shaft. When the shaft is slidably moved relative to the surrounding catheter, the second portion of the expandable member can be released from the shaft, and the shaft can be withdrawn or removed.

Provided herein are methods and systems for the removal of anatomical occlusions, and an occlusion removal device comprising a first body adapted to be mounted to a delivery wire and releasably engaged to the delivery wire, wherein while engaged the first body remains fixed on the delivery wire and upon release moves axially along the delivery wire, and a second body adapted to be mounted to the delivery wire. A first proximal body may be oriented proximally to a second distal body. The proximal body and the distal body may be adapted to expand upon exiting a delivery catheter. The proximal body may be releasably engaged by a mechanically breakable connection or an electrolytically or heat disconnectable connection, the electrolytically disconnectable connection being broken upon an application of electric current to the electrolytically disconnectable connection.

A medical device comprising a tube having first segment comprising a primary opening at the proximal end nearest an external termination device; and a second segment comprising a secondary opening at the distal end; and a side-hole dividing the first segment and the second segment, wherein the internal diameter of the first segment is greater than the internal diameter of the second segment, and the tube has no pre-formed curved configuration. The first segment extends from the primary opening to the side-hole and the second segment extends from the side-hole to the secondary opening. The side-hole and first segment form a non-support lumen, and the second segment forms a support lumen. The support lumen is effective to provide stability to the non-support lumen of the tube, to anchor the tube within an anchor area, and to prevent prolapse of the medical device elements due to a counterforce against the tube by the second device(s) being delivered through the tube to a more distal location of a target area; and to facilitate placement of the second medical device into the target area.

A method of using the medical device described.