Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

An aspiration system includes an aspiration catheter including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of an elongate tubular member and into the vasculature of a subject, an elongate support member coupled to the tubular aspiration member and extending between the proximal end of the aspiration catheter and the proximal end of the tubular aspiration member, a high pressure injection lumen extending within the elongate support member and having a distal end including a curved portion configured to change a direction of fluid flow by at least about 90°, at least one orifice located at the distal end of the high pressure injection lumen configured to allow liquid to be released into the lumen of the tubular aspiration member, and an annular seal carried by the tubular aspiration member and configured to create a liquid seal against the inner surface of the elongate tubular member.

An insertable device is designed to control uterine hemorrhaging after birth by facilitating contractile movement of the uterus. An insertable device comprises a tube having a connecting portion and a suction portion and a seal positioned along the length of the connecting portion proximal to the suction portion. Upon insertion of the suction portion and seal into the uterus, the seal abuts a vaginal canal and forms a seal between a vaginal opening and the uterus. The suction portion comprises a first loop having an opening that is oriented away from an interior wall of the uterus when inserted into the uterus. The connecting portion of the tube couples to a pump that when actuated generates a negative pressure within the uterus, resulting in a uniform mechanical stimulus to the uterine wall in order to facilitate tamponade and contractile movement of the tissue.

A medical device for removing an object in a body cavity includes a rotatable drive shaft having a lumen, a cutter at a distal portion of the shaft and by which the object is cut, a first rotation connection portion at a proximal portion of the shaft and by which a rotational force is transmitted to the shaft, a first fluid connection portion at the proximal portion and through which the object is removed with a fluid, and a handle including a second rotation connection portion connectable to the first rotation connection portion, a second fluid connection portion connectable to the first fluid connection portion, a rotation driving source connected to the second rotation connection portion and generating the rotational force, and a fluid driving source moving the fluid from the distal to proximal portions of the shaft via the first and second fluid connection portions.

An apparatus including a housing, an electrical conductor, and a suction control valve. The housing forms a handle and a shaft. The housing defines a suction channel from a distal end of the shaft. The electrical conductor extends to the distal end of the shaft. The suction control valve is connected to the suction channel at the handle. The suction control valve includes a valve body having a first channel and a second channel connected to the first channel, where the first channel forms a portion of the suction channel; and a valve barrel rotatably connected to the valve body. The valve barrel includes a rotatable ring extending around the handle and forming a portion of the housing. The ring includes an orifice configured to be rotated into and out of registration with an end of the second channel as the ring is rotated about the valve body.

A method of performing a medical procedure in a cerebral vessel of a patient including advancing a first catheter system towards an embolus within a cerebral blood vessel and a second catheter system towards the embolus through the first catheter, applying aspiration pressure through the lumen of the second catheter; anchoring a distal end of the second catheter onto the embolus via the aspiration pressure; applying a proximally-directed force on the second catheter; and advancing the first catheter over the second catheter towards the embolus while the distal end of the second catheter remains anchored onto the embolus; and automatically applying aspiration pressure within the first catheter upon the second catheter portion entering into the first catheter.

Aspiration systems and methods for controlling blood loss during thrombus removal are disclosed herein. The systems include an aspiration catheter, an aspiration tubing, a receptacle for collecting aspirated blood, a vacuum line coupled to the receptacle, and a sensor configured to measure a flow parameter associated with a liquid within an aspiration lumen. The systems further include a regulator configured to adjust a vacuum pressure within the vacuum line, and a vacuum controller operably coupled to the sensor and the regulator. The vacuum controller is configured to receive the flow parameter from the sensor, compare the flow parameter to a target range for the flow parameter, and send an automatic control signal to the regulator based on a comparison of the flow parameter to the target range. The automatic control signal causes the regulator to adjust the vacuum pressure within the vacuum line.

The present invention provides a percutaneous vascular surgical system for performing endovascular/neurovascular interventions, the system incorporating a sheath having a proximal end and a distal end and defining a main lumen extending between the proximal and distal ends, an auxiliary lumen also defined by the sheath, a reversibly inflatable balloon located about the sheath adjacent the distal end and in fluid communication with the auxiliary lumen, a syringe selectively connectable to the main lumen to create suction through the main lumen, and a vessel closure device for the closure of the arteriotomy, the surgical system and method of the invention having utility in a large number of percutaneous vascular procedures such as carotid artery stenosis or neurovascular interventions and enabling four procedures to be performed with one system, being percutaneous access, emboli removal, flow reversal and arteriotomy closure.

A method may include positioning a first device within an internal carotid artery of a subject and impeding antegrade blood flow in the internal carotid artery. Additionally, the method may include delivering a pharmaceutical agent through an external carotid artery for passage into an ophthalmic artery of the subject.

A robotic system is configured to automatically trigger a robotic action based on an identified phase of a medical procedure. The robotic system includes a video capture device; a robotic manipulator; one or more sensors; an input device; and control circuitry. The control circuitry is configured to: determine a first status of the robotic manipulator based on sensor data from the one or more sensors; identify a first input from the input device for initiating a first action of the robotic manipulator; perform a first analysis of a video of a patient site captured by the video capture device; identify a first phase of the medical procedure based at least in part on the first status of the robotic manipulator, the first input, and the first analysis of the video; and trigger a first automatic robotic action of the robotic manipulator based on the identified first phase.