A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.

A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. The medical device may further include a snare device configured to transition between a contracted state within the lumen of the insertion device, and an expanded state extending distally of the insertion device. The snare device may include a loop including a pair of legs and a distal tip. The distal tip may include a plurality of stabilizers between the pair of legs.

Method of endovascular intervention in neurovascular anatomy of a patient including deploying an anchor of a tethering device in an anchoring vessel of a neurovascular anatomy, the anchor coupled to a tether extending proximally from the anchor. Method includes advancing a guide-sheath over the tether of the tethering device anchored in the anchoring vessel and attached to the tether, the guide-sheath includes at least one lumen and a distal opening from the lumen. Method includes advancing a treatment device through the lumen of the guide-sheath and out the distal opening from the at least one lumen and through an entrance of a target intracranial vessel, and deploying the treatment device at a treatment site within the target intracranial vessel without a combined therapy of two or more anti-platelet therapeutic agents during a peri-procedural period. Related systems, devices, and methods are disclosed.

A containing element is used to capture material in a blood vessel for removal. The containing element is advanced through the blood vessel or a catheter in a constricted configuration. A control body is coupled to the containing element which assists moving the containing element. In some embodiments, the containing element is used for restricting blood flow within a vessel.

A containing element is used to capture material in a blood vessel for removal. The containing element is advanced through the blood vessel or a catheter in a constricted configuration. A control body is coupled to the containing element which assists moving the containing element. In some embodiments, the containing element is used for restricting blood flow within a vessel.

A left atrium appendage (LAA) isolator, including: a body sized and shaped to fit an at least partially inverted LAA of a human adult, wherein a distal end of said body defines a two-state sealing adaptor interface configured in a first state to apply a radially outward force against a wall of said LAA or against a wall of said LAA opening sufficient to anchor said body to the LAA wall, and in a second state the sealing adaptor interface is configured to apply a radially inward force on a portion of the inverted LAA positioned within said body.

An intraluminal device includes a radially expandable body and a control member operable to expand and contract the radially expandable body. The radially expandable body comprises plural sets of first filaments spiraling in a first direction from a proximal end portion to a distal end portion of the radially expandable body and plural sets of second filaments spiraling in a second direction from the proximal end portion to the distal end portion. The plural sets of first filaments intersect the plural sets of second filaments, forming plural cross sections of the radially expandable body. At least one of the plural sets of first filaments comprises a filament constructed of a radiopaque material.

An intraluminal device includes a radially expandable body and a control member operable to expand and contract the radially expandable body. The radially expandable body comprises plural sets of first filaments spiraling in a first direction from a proximal end portion to a distal end portion of the radially expandable body and plural sets of second filaments spiraling in a second direction from the proximal end portion to the distal end portion. The plural sets of first filaments intersect the plural sets of second filaments, forming plural cross sections of the radially expandable body. At least one of the plural sets of first filaments comprises a filament constructed of a radiopaque material.

A tissue retrieval system including a tissue retrieval bag deployable by an actuator from an introducer and suspended in an open configuration by support arms can be serially redeployed between a partially or fully stowed configuration and a first deployed configuration to be used in procedures to collect multiple samples. The system can include defeasible proximal and distal stop mechanisms to limit movement of the actuator for serial redeployment. The tissue retrieval system can include a retention latch to couple a bead of the tissue retrieval bag to the actuator with the retrieval bag in the first deployed position and a user-selectable deployment release to allow deployment of the retrieval bag to a fully deployed position where it is released from the actuator. A bead stop is positioned to engage the introducer to prevent reintroduction of the bead and bag into the introducer once the bag has been fully deployed.

A tissue retrieval system including a tissue retrieval bag deployable by an actuator from an introducer and suspended in an open configuration by support arms can be serially redeployed between a partially or fully stowed configuration and a first deployed configuration to be used in procedures to collect multiple samples. The system can include defeasible proximal and distal stop mechanisms to limit movement of the actuator for serial redeployment. The tissue retrieval system can include a retention latch to couple a bead of the tissue retrieval bag to the actuator with the retrieval bag in the first deployed position and a user-selectable deployment release to allow deployment of the retrieval bag to a fully deployed position where it is released from the actuator. A bead stop is positioned to engage the introducer to prevent reintroduction of the bead and bag into the introducer once the bag has been fully deployed.