The invention relates to trans-epithelial frictionally abrasive tissue sampling devices for performing biopsies and methods of inducing an immune response against a pathogen, wherein epithelial cells containing the pathogen are disrupted with the frictionally abrasive tissue sampling device to introduce the pathogen into the bloodstream of a patient.

The invention is a device, system, and method for repairing heart valve function, which may include bisecting native valve leaflets for improved deployment of a prosthetic heart valve in the native valve annulus. The invention may include a catheter having a cutting element shaft with a cutting element configured to puncture a valve leaflet and/or make a controlled cut through the leaflet. The device may have an extendable foot configured to be positioned on an opposite side of the valve leaflet from the cutting element shaft. The device may include magnets to guide the cutting element and/or cutting element shaft in proper alignment with the extendable foot and to hold the elements in place during leaflet bisection.

This document describes rotational atherectomy devices and systems for removing or reducing stenotic lesions in blood vessels by rotating an abrasive element within the vessel to partially or completely remove the stenotic lesion material.

A formula and method to counteract hair loss, where the formula is a mixture. The mixture consists of Flaxseed oil, Coconut oil, Castor oil, Nigella sativa oil, Olive oil, Sesame oil, Sweet Almond oil, Bitter Almond oil, Watercress oil, Jojoba oil, Garlic oil, Onion oil, and Pistacia lentiscus oil. The oils derived from seeds are cold rolled to produce the oil. The mixture is applied to the scalp after brushing and washing of the scalp area to be treated.

The present disclosure provides a medical shaver including: a shaver body (10) having a hollow portion therein; a shaft (20) having one end rotatably attached inside the shaver body and having a motor attachment part provided on the other end that is exposed outside the shaver body; a suction tube (30) rotatably attached to the hollow portion of the shaver body and having one end detachably coupled to the shaft so as to be rotated together with the shaft; a first seating groove (27) provided on an inner circumferential surface of the shaft; a second seating groove (33) provided on an outer circumferential surface of the suction tube; and a spring (s) located in the first and second seating grooves and coupling the shaft and the suction tube, in which the spring (s) has a structure in which both ends of a coil spring are connected to form a ring shape.

Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating an abrasive element within the vessel. The abrasive element can be attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly.

According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end, a cartridge comprising an interior cavity and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit and a waste conduit. In addition, the cartridge is coupled to the handpiece assembly with the interior cavity of the cartridge being in fluid communication with the fluid delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip, a first opening in fluid communication with the fluid delivery conduit, a second opening in fluid communication with the waste conduit and an abrasive element. The first opening, the second opening and the abrasive element of the tip are generally positioned within the peripheral lip.

An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

A personal care appliance includes a housing, a drive assembly provided in the housing, and a workpiece member. The drive assembly includes a stator and an armature adjacent the stator, wherein the stator, when energized, is structured to cause the armature to oscillate back and forth. The personal care appliance further includes a mounting assembly having a pivot arm having a shaft member and first and second mounting members. The workpiece member is coupled to the first end portion of the shaft member such that oscillation of the armature causes the workpiece member to oscillate relative to the housing.