A suturing device comprises a housing (1) having operating handles at one end and two clamping working jaws (2 and 3) at the other end, at least one of which (jaw 3) is mounted for movement relative to the second. The device also comprises: a receptacle (capsules 18) having a quick-setting, biocompatible, fluid material, which is used as a means for fastening tissues, wherein at the outlet of said receptacle is a controllable screen, for example a membrane, which is destroyed when the pressure in the receptacle is increased to a set level; and a mechanism for feeding the fluid material into a suturing zone. The working jaw (3) is hollow, and disposed therein are capsules (18) which comprise the fluid material and communicate, via the outlet, with dies (21) which are designed in a wall of the working jaw (3) that interacts with the suturable tissues. The mechanism for feeding the fluid material is designed to be capable of increasing the pressure inside the capsules (18) and forming streams of the fluid material which pass through the dies (21) at a pressure sufficient for passing through the suturable tissues.

Intravascular devices and methods for intramural delivery of dissection fluids and infusates are disclosed herein. In some embodiments, the systems include an infusion assembly that can access a position in vessel adjacent an infusion site and advance a tissue manipulation component into the infusion site to deliver a therapeutic infusate. The infusion site can be an intraluminal space, such as within an obstructive material, adjacent the obstructive material, and/or within a boundary layer between the obstructive material and a vessel wall. The infusion assembly can further deliver an infusate that includes a therapeutic drug or other agent into the infusion site.

A liquid ejection nozzle that has a nozzle hole and ejects a liquid from the nozzle hole in a ejection direction toward a target subject includes a nozzle plate having the nozzle hole, and a pressing member having a through hole having a diameter larger than a diameter of the nozzle hole at a position corresponding to the nozzle hole in the ejection direction and configured to press the nozzle plate from a downstream side in the ejection direction.

The invention provides a filter assembly including a string or wire such that a lasso type cincture is effected, said filter being openable and closeable while in deployed within a bodily vessel. A string lengthen or shorting adjustment mechanism, such as a ratchet or reel allows more length of string into the device or alternatively to shorten the length of available string in the system. The described invention, when used to ameliorate venous clots and most arterio-venous dialysis grafts, a filter-tipped aspirator is used downstream from the clot to capture and remove dislocated emboli. A method of using same is disclosed.

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and/or skin repositioning and/or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

This disclosure describes techniques and devices for improvement of surgical outcomes for tissue removal surgeries. A surgical instrument with adjustable and selective resection is described. The disclosed devices and methods allow selective tissue removal.

This disclosure describes techniques and devices for improvement of surgical outcomes for tissue removal surgeries. A surgical instrument with adjustable and selective resection is described. The disclosed devices and methods allow selective tissue removal.

Provided is a medical device comprising a handle comprising a distal hub, a proximal hub, and a middle hub disposed between the distal hub and the proximal hub. The medical device may comprise an outer sheath coupled with the distal hub, a basket configurable in a deployed state and an undeployed state, and a jet tube shaft coupled with the proximal hub, the jet tube shaft coaxial to the outer sheath. The jet tube shaft may comprise a jet tube comprising an aperture configured to expel a fluid, a jet tube lumen sized to accept the jet tube, and an evacuation lumen.

A fluid stream is directed toward tissue to generate a plurality of shedding clouds. The fluid stream can be scanned such that the plurality of shedding clouds arrive a different overlapping locations. Each of the plurality of shedding clouds can remove a portion of the tissue. In many embodiments, an apparatus to ablate tissue comprises a source of pressurized fluid, and a nozzle coupled to the source of pressurized fluid to release a fluid stream, in which the fluid stream generates a plurality of shedding clouds.

A fluid stream is directed toward tissue to generate a plurality of shedding clouds. The fluid stream can be scanned such that the plurality of shedding clouds arrive a different overlapping locations. Each of the plurality of shedding clouds can remove a portion of the tissue. In many embodiments, an apparatus to ablate tissue comprises a source of pressurized fluid, and a nozzle coupled to the source of pressurized fluid to release a fluid stream, in which the fluid stream generates a plurality of shedding clouds.