A method for treating a patient having thrombus includes providing a manipulation device including a housing configured to be supported by the hand of a user and having a distal and proximal end, a drive system disposed within the housing, and configured to rotate a rotation member, an engagement member coupled to the rotation member and configured to be removably coupled to an elongate medical device, an activation member carried by the housing such that it can be operated by at least a portion of the hand of the user when the housing is supported by the hand of the user, the drive system configured to apply motive force to the engagement member, securing an elongate member to the engagement member, introducing at least the distal end of the elongate member into a blood vessel adjacent a thrombus, operating the activation member to cause at least some rotation of the rotation member, which in turn causes at least some rotation of the distal end of the elongate member at or near the thrombus, and aspirating at least some of the thrombus with an aspiration catheter.

The invention provides a filter assembly including a string or wire such that a lasso type cincture is effected, said filter being openable and closeable while in deployed within a bodily vessel. A string lengthen or shorting adjustment mechanism, such as a ratchet or reel allows more length of string into the device or alternatively to shorten the length of available string in the system. The described invention, when used to ameliorate venous clots and most arterio-venous dialysis grafts, a filter-tipped aspirator is used downstream from the clot to capture and remove dislocated emboli. A method of using same is disclosed.

Disclosed are methods for performing endoscopy comprising directing a distal end of an endoscope to proximity of a portion of a surface of a bodily cavity; and directing a liquid-gas stream at a portion of the surface of the bodily cavity. Disclosed are also devices useful in endoscopy, comprising: an elongated body having a proximal end and a distal end; a nozzle at the distal end; a gas channel configured for conveying a gas from the proximal end to the nozzle; and a liquid channel configured for conveying a liquid from the proximal end to the nozzle, wherein the nozzle is configured to generate a liquid-gas stream directed in a specified direction from a gas conveyed by the gas channel and a liquid conveyed by the liquid channel.

Disclosed are methods for performing endoscopy comprising directing a distal end of an endoscope to proximity of a portion of a surface of a bodily cavity; and directing a liquid-gas stream at a portion of the surface of the bodily cavity. Disclosed are also devices useful in endoscopy, comprising: an elongated body having a proximal end and a distal end; a nozzle at the distal end; a gas channel configured for conveying a gas from the proximal end to the nozzle; and a liquid channel configured for conveying a liquid from the proximal end to the nozzle, wherein the nozzle is configured to generate a liquid-gas stream directed in a specified direction from a gas conveyed by the gas channel and a liquid conveyed by the liquid channel.

A medical instrument includes a tubular cutter extending along an axis and having a windowed outer sleeve and a moveable inner cutting sleeve. An ultrasound transducer is operatively coupled to the inner cutting sleeve in order to induce motion in the inner cutting sleeve to enhance cutting or resection of tissue by the inner cutting sleeve as it is reciprocated or otherwise moved past the cutting window. The instrument typically will include a motor drive configured to reciprocate and/or rotate the inner cutting sleeve relative to the windowed outer sleeve, usually at a reciprocation rate between 1 and 10 Hz.

The present disclosure relates generally to bicycles. In particular, the present disclosure provides systems and devices for converting a standard bicycle into a cargo bicycle using various detachable components. The ability to convert a standard bicycle into a cargo bicycle and back again confers many advantages, including eliminating the need for a separate bicycle for transporting cargo and encouraging the use of bicycles as a mode of transportation.

Methods for removing blockages and preventing thromboembolic injuries, by advancing to a blockage a first tubular, endovascular device receiving irrigating fluid through a proximal opening, having a circumferential wall, lumen, at least one distal side hole oriented angularly to a distal opening; ejecting fluid from the side hole(s) to irrigate a blockage; introducing a second catheter for aspiration, comprising a circumferential wall having a proximal and distal opening, a flared, semi-permeable filter at the distal end for removal of emboli through the second lumen; advancing the second device to a blood vessel receiving blood from the blocked vessel, aspirating the blockage, axially rotating the first endovascular device having at least one half-loop to macerate an obstruction, capturing and removing emboli from the blockage through the second endovascular device which prevents emboli from causing further blockage of blood vessels. Variants of said method including a third rotatable device.

A surgical instrument (1) is provided with a rigid probe (2), and cuts off the trabecular meshwork by inserting this probe (2) into the canal of Schlemm. An inner tube portion having a cutter is equipped inside the probe, and the trabecular meshwork sucked in from a hole portion (22) is cut off by the cutter due to the movement of the inner tube portion. A protection portion (21) is formed on the tip the probe (2) and protects the outer wall of the canal of Schlemm when cutting the trabecular meshwork. According to the invention, an ophthalmic surgical instrument for glaucoma patients is provided, the surgical instrument having excellent operability and preventing cutting of parts that should not be cut off without fail.

A surgical instrument (1) is provided with a rigid probe (2), and cuts off the trabecular meshwork by inserting this probe (2) into the canal of Schlemm. An inner tube portion having a cutter is equipped inside the probe, and the trabecular meshwork sucked in from a hole portion (22) is cut off by the cutter due to the movement of the inner tube portion. A protection portion (21) is formed on the tip the probe (2) and protects the outer wall of the canal of Schlemm when cutting the trabecular meshwork. According to the invention, an ophthalmic surgical instrument for glaucoma patients is provided, the surgical instrument having excellent operability and preventing cutting of parts that should not be cut off without fail.

A thrombectomy catheter deployment for operation of a thrombectomy catheter may include a stand alone drive unit and a disposable pump/catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly may have a plurality of preconnected components including a tubular structure and a thrombectomy catheter connected thereto. A barcode reader may sense specific operational data pertaining to an individual pump and may provide an interface for operation of the reciprocating linear actuator.