Exemplary embodiments of the present disclosure provide method and apparatus for facilitating stretching of a biological tissue by forming a plurality of micro-slits in the tissue. Each micro-slit can be less than about 2 mm or less than about 1.5 mm long, or even less than about 1 mm, such that small gaps that can heal quickly can be formed when the tissue is stretched. The micro-slits can be formed using a plurality of cutting arrangements or an ablative laser. The micro-slits can be formed in various patterns, including staggered rows, circular or spiral patterns, or random patterns.

Exemplary embodiments of the present disclosure provide method and apparatus for facilitating stretching of a biological tissue by forming a plurality of micro-slits in the tissue. Each micro-slit can be less than about 2 mm or less than about 1.5 mm long, or even less than about 1 mm, such that small gaps that can heal quickly can be formed when the tissue is stretched. The micro-slits can be formed using a plurality of cutting arrangements or an ablative laser. The micro-slits can be formed in various patterns, including staggered rows, circular or spiral patterns, or random patterns.

A cutting device is provided having multiple evenly-spaced cutting blades and which is useful for producing tissue forms comprising membranous tissue fragments which are relatively uniformly sized and shaped. The present invention also relates to methods for using the cutter device to quickly and efficiently produce such tissue forms which are useful as grafts and can be flowable and easily passable through a luer-slip tip syringe or needle.

A cutting device is provided having multiple evenly-spaced cutting blades and which is useful for producing tissue forms comprising membranous tissue fragments which are relatively uniformly sized and shaped. The present invention also relates to methods for using the cutter device to quickly and efficiently produce such tissue forms which are useful as grafts and can be flowable and easily passable through a luer-slip tip syringe or needle.

A system comprising a handpiece and drive system configured to removably couple to a proximal end of a housing. A scalpet assembly is configured to removeably couple to the housing, and includes a scalpet array comprising at least one scalpet configured for rotation. The scalpet array is configured to harvest dermal plugs via fractional resection. A collection chamber is configured to collect the dermal plugs, and to house formation of an injectable filler by mincing the dermal plugs, and mixing the dermal plugs with a carrier. The injectable filler is configured for bulk fill. The collection chamber includes a loading port, and a cannular syringe is configured to mate with the loading port to receive the injectable filler, and to deliver the injectable filler for the bulk fill.

A system comprising a handpiece and drive system configured to removably couple to a proximal end of a housing. A scalpet assembly is configured to removeably couple to the housing, and includes a scalpet array comprising at least one scalpet configured for rotation. The scalpet array is configured to harvest dermal plugs via fractional resection. A collection chamber is configured to collect the dermal plugs, and to house formation of an injectable filler by mincing the dermal plugs, and mixing the dermal plugs with a carrier. The injectable filler is configured for bulk fill. The collection chamber includes a loading port, and a cannular syringe is configured to mate with the loading port to receive the injectable filler, and to deliver the injectable filler for the bulk fill.

A fascia lata graft harvesting apparatus that is intended to be used in surgical interventions and that allows the fascia to be harvested safely. The apparatus includes a metal part shaped like a guide strip placed under the fascia lata, a cutting tool which enables to free the graft by the shearing effect created by the end part thereof, and a clamp which fixes the fascia on the guide metal strip, thereby preventing it from sliding and at the same time ensuring that the guide metal strip is kept in position.

The palatal gingival graft harvesting device is a gripping tool for holding and manipulating palatal gingival grafts. The palatal gingival graft harvesting device includes a first arm having opposed first and second ends, and a second arm also having opposed first and second ends. The first arm and the second arm are pivotally joined to one another at a pivot joint adjacent the second ends thereof. The first end of the second arm has an opening formed therein for receiving a tip of the first end of the first arm. First and second bifurcated, U-shaped gripping jaws extend orthogonally from the second ends of the first and second arms. Central portions of the first and second arms are selectively and releasably lockable to one another to clamp the graft between the gripping jaws.

The palatal gingival graft harvesting device is a gripping tool for holding and manipulating palatal gingival grafts. The palatal gingival graft harvesting device includes a first arm having opposed first and second ends, and a second arm also having opposed first and second ends. The first arm and the second arm are pivotally joined to one another at a pivot joint adjacent the second ends thereof. The first end of the second arm has an opening formed therein for receiving a tip of the first end of the first arm. First and second bifurcated, U-shaped gripping jaws extend orthogonally from the second ends of the first and second arms. Central portions of the first and second arms are selectively and releasably lockable to one another to clamp the graft between the gripping jaws.

Embodiments include a system comprising a cannula assembly configured for rotational fractional resection (RFR). The cannula assembly includes at least one cannula configured for rotational operation and enclosed in a depth guide configured to control an insertion depth of the at least one cannula. The depth guide includes a vacuum chamber configured to maintain vacuum to evacuate resected tissue generated by the RFR.