One aspect of the present disclosure includes a delivery tool configured to deliver a neurostimulator into a pterygopalatine fossa of a subject. The neurostimulator can include a body connected to an integral stimulation lead having one or more stimulating electrodes. The delivery tool can comprise a handle, an elongated shaft extending from the handle, a hub portion, and a double barrel sheath. The hub portion can be located between the shaft and a spine member that extends axially away from the hub portion. The hub portion can be sized and dimensioned to releasably mate with the neurostimulator. The double barrel sheath can be connected to the spine member. A central lumen can extend through at least a portion of the shaft and the hub portion. The central lumen can be adapted to receive a lead ejector for selective deployment of the stimulation lead from the double barrel sheath.

A transport system for delivery or retrieval of a biostimulator, such as a leadless cardiac pacemaker, is described. The biostimulator transport system includes a docking cap supported by a bearing within a bearing housing. The bearing allows relative rotation between a torque shaft connected to the docking cap and an outer catheter connected to the bearing housing. The bearing housing and the docking cap include respective bearing retainers that constrain the bearing within the bearing housing without a weld attachment. The weldless retainers of the biostimulator transport system provide a robust mechanical securement of the bearing that is not vulnerable to corrosion. Other embodiments are also described and claimed.

Systems and methods are provided for performing a hair transplant using a hair transplant device. The hair transplant device comprises an extraction unit including a coring needle configured to extract at least one hair follicle from a donor site, an implanting unit removably coupled to the extraction unit, the implanting unit including a splitting needle configured to create an opening in a recipient site, a housing coupled to the extraction unit, and a user interface extending from the housing and moveable relative to the housing. The user interface includes a pin movable within the coring needle relative to the housing.

A surgical instrument, and methods for its use, is described that includes clamp heads that can be nestled within or extended from a tubular sheath by longitudinal movement of the clamp heads' tines with respect to the tubular sheath. One of the tines includes an arch that slides against a mouth and inside wall of the tubular sheath, causing the clamp heads to open or close. The clamp heads close lightly, to within a predetermined (or zero) distance from one another, gently grasp an ultrathin polymer substrate seeded with cells, and pulls it within the sheath such that the substrate curls and folds to protect the cells.

A device for continuously monitoring glucose levels in a patient is disclosed. The device includes a glucose electronics assembly and a glucose lead assembly in electrical communication with the glucose electronics assembly. The glucose electronics assembly is configured to be positioned in the subcutaneous tissue and the glucose lead assembly is configured to be positioned in a vessel of the patient. The glucose lead assembly has a central shaft, a first electrode in physical communication with the central shaft, a second electrode in physical communication with the central shaft, a third electrode in physical communication with the central shaft and a positioning element configured to have an undeployed state and a deployed state. In the undeployed state, the positioning element is substantially linear, and in the deployed state, the positioning element extends away from the central shaft.

An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.

A surgical instrument comprising a jaw assembly is disclosed. The surgical instrument further comprises a motor-driven drive system configured to open the jaw assembly. The surgical instrument also comprises a control system configured to control the drive system and, also, control a power supply system configured to supply electrical power to electrodes defined in the outer surface, or outer surfaces, of the jaw assembly. In use, the surgical instrument can be used to apply mechanical energy and electrical energy to the tissue of a patient at the same time, or at different times. In certain embodiments, the user controls when the mechanical and electrical energies are applied. In some embodiments, the control system controls when the mechanical and electrical energies are applied.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

A subcutaneously implantable device is implantable into a body of a patient, and includes a prong and an electrode. The prong has a contact portion at or adjacent to a distal end thereof that is configured to contact an organ. The prong is constructed to apply pressure to the organ with spring action so as to maintain contact between the contact portion and the organ without fixing the contact portion to the organ. The electrode is provided at the contact portion of the prong, is configured to contact the organ, and is electrically coupled or couplable with circuitry that is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to the organ.

The disclosure relates to a device for creating an intradermal channel in a skin tissue of a patient, with a thread. The device can include a main body, a penetration element, and a displacement mechanism. The main body can have a lumen. The penetration element can be at a distal end of the main body and have a cannula which is configured to contain the thread in its entirety. The displacement mechanism can have at least a portion thereof permanently contained within the lumen of the main body. The displacement mechanism can be configured to effect a relative motion between the cannula and the thread, thereby to expose at least a portion of the thread to a patient's tissue within an intradermal channel.