Patent classifications
C07C215/12
Steroids as agonists for FXR
The invention relates to compounds of formula (I): ##STR00001## wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.
Steroids as agonists for FXR
The invention relates to compounds of formula (I): ##STR00001## wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.
Storage-stable dye solutions
The present invention relates to storage-stable dye salts, solutions and compositions thereof a process for their preparation and their use for dyeing and/or printing substrates.
Storage-stable dye solutions
The present invention relates to storage-stable dye salts, solutions and compositions thereof a process for their preparation and their use for dyeing and/or printing substrates.
Synergistic compositions
The present invention describes a synergistic composition comprising of one or more statins, or one or more dipeptidyl peptidase IV (DPP IV) inhibitor or one or more biguanide antihyperglycaemic agent and a PPAR agonist of formula (Ia) for the treatment of diabetes, especially non-insulin dependent diabetes (NIDDM) or Type 2 diabetes and conditions associated with diabetes mellitus and to compositions suitable for use in such method. The invention also describes the preparation of such compositions. The present invention also relates to certain novel salts of the PPAR agonist of formula (I), processes for the preparation of these novel salts and use thereof. ##STR00001##
Synergistic compositions
The present invention describes a synergistic composition comprising of one or more statins, or one or more dipeptidyl peptidase IV (DPP IV) inhibitor or one or more biguanide antihyperglycaemic agent and a PPAR agonist of formula (Ia) for the treatment of diabetes, especially non-insulin dependent diabetes (NIDDM) or Type 2 diabetes and conditions associated with diabetes mellitus and to compositions suitable for use in such method. The invention also describes the preparation of such compositions. The present invention also relates to certain novel salts of the PPAR agonist of formula (I), processes for the preparation of these novel salts and use thereof. ##STR00001##
Quality and color of ethanolamine product streams by reduced temperature at the triethanolamine column
Systems and methods for producing a colorless triethanolamine product stream with a degree of purity of greater than or equal to 99% by weight from the triethanolamine distillation columns in a non-reactive distillation process. The desired triethanolamine product stream can be obtained by increasing the bottom stream flow rate at the diethanolamine column by 80 kilograms per hour, and reducing the triethanolamine product stream flow rate by 500 kilograms per hour. This process can result in a reduction of the temperature at the triethanolamine column by up to 23.5 degrees. The reduced temperature can result in a triethanolamine product stream with an APHA color of 0 to less than 50, for example, 0 to 40, for example, 0 to 30, for example 0 to 20, and for example, 0 to 10.
Quality and color of ethanolamine product streams by reduced temperature at the triethanolamine column
Systems and methods for producing a colorless triethanolamine product stream with a degree of purity of greater than or equal to 99% by weight from the triethanolamine distillation columns in a non-reactive distillation process. The desired triethanolamine product stream can be obtained by increasing the bottom stream flow rate at the diethanolamine column by 80 kilograms per hour, and reducing the triethanolamine product stream flow rate by 500 kilograms per hour. This process can result in a reduction of the temperature at the triethanolamine column by up to 23.5 degrees. The reduced temperature can result in a triethanolamine product stream with an APHA color of 0 to less than 50, for example, 0 to 40, for example, 0 to 30, for example 0 to 20, and for example, 0 to 10.
ADDITIVE FOR SURFACE ACTIVATION, AND EMULSION COMPOSITION USING SAME
The present invention addresses the problem of providing a novel additive for surface activation and an emulsion composition using same, in which an excellent emulsion stability is obtained. The present invention also addresses the problem of improving the usage feel in a cosmetic and the lubrication performance in a lubricant. This additive for surface activation is one in which the following components (A) and (B) are compounded. (A) An amine or ammonium compound having a hydroxyaliphatic hydrocarbon group that contains one or more hydroxy groups and optionally contains an oxygen atom unassociated with the hydroxy groups; and (B) an unsaturated or branched aliphatic acid having 8 to 22 carbon atoms or a salt thereof. In addition, this emulsion composition is one in which the above additive has been added.
ADDITIVE FOR SURFACE ACTIVATION, AND EMULSION COMPOSITION USING SAME
The present invention addresses the problem of providing a novel additive for surface activation and an emulsion composition using same, in which an excellent emulsion stability is obtained. The present invention also addresses the problem of improving the usage feel in a cosmetic and the lubrication performance in a lubricant. This additive for surface activation is one in which the following components (A) and (B) are compounded. (A) An amine or ammonium compound having a hydroxyaliphatic hydrocarbon group that contains one or more hydroxy groups and optionally contains an oxygen atom unassociated with the hydroxy groups; and (B) an unsaturated or branched aliphatic acid having 8 to 22 carbon atoms or a salt thereof. In addition, this emulsion composition is one in which the above additive has been added.