The present invention provides compositions and methods for relieving pain at a site in a human or animal in need thereof by administering at a discrete site in a human or animal in need thereof a dose of capsaicin in an amount effective to denervate a discrete site without eliciting an effect outside the discrete location, the dose of capsaicin ranging from 1 g to 3000 g.

Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

Disclosed are compositions and methods for preventing or reducing polymer formation and polymer deposition in equipment used in petrochemical processes. An antifoulant composition includes a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents. A method of preventing or reducing fouling of process equipment used in an industrial process is also described. The method includes introducing into the process equipment an antifoulant composition, the antifoulant composition comprising a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents.

Disclosed are compositions and methods for preventing or reducing polymer formation and polymer deposition in equipment used in petrochemical processes. An antifoulant composition includes a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents. A method of preventing or reducing fouling of process equipment used in an industrial process is also described. The method includes introducing into the process equipment an antifoulant composition, the antifoulant composition comprising a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents.

Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.

Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.

The present invention relates to lyso-diacylglyceryltrimethylhomoserine (lyso-DGTS) or derivatives thereof for use in the treatment of atherosclerotic cardiovascular disease, and further provides particular such lyso-DGTS derivatives.

Disclosed are compositions and methods for preventing or reducing polymer formation and polymer deposition in equipment used in petrochemical processes. An antifoulant composition includes a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents. A method of preventing or reducing fouling of process equipment used in an industrial process is also described. The method includes introducing into the process equipment an antifoulant composition, the antifoulant composition comprising a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents.

Disclosed are compositions and methods for preventing or reducing polymer formation and polymer deposition in equipment used in petrochemical processes. An antifoulant composition includes a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents. A method of preventing or reducing fouling of process equipment used in an industrial process is also described. The method includes introducing into the process equipment an antifoulant composition, the antifoulant composition comprising a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents.