Patent classifications
C07C233/47
N-ACYL AMINO ACID SURFACTANTS AND DERIVATIVES THEREOF
Surfactant compositions and derivatives with low amounts of impurities are disclosed along with a method of making the same. A surfactant composition includes greater than 80% by weight of N-acyl amino acid surfactant of formula (I) and is substantially free of solvents and/or NaCl. A process for preparing an N-acyl amino acid surfactant includes combining an amino acid, a waterless base and a fatty alkyl ester of formula (III) to form a mixture that includes an amino acid salt of formula (II). The temperature of the mixture is increased to form a reaction mixture. Alkyl alcohol is removed from the reaction mixture, and the reaction mixture becomes substantially clear.
N-ACYL AMINO ACID SURFACTANTS AND DERIVATIVES THEREOF
Surfactant compositions and derivatives with low amounts of impurities are disclosed along with a method of making the same. A surfactant composition includes greater than 80% by weight of N-acyl amino acid surfactant of formula (I) and is substantially free of solvents and/or NaCl. A process for preparing an N-acyl amino acid surfactant includes combining an amino acid, a waterless base and a fatty alkyl ester of formula (III) to form a mixture that includes an amino acid salt of formula (II). The temperature of the mixture is increased to form a reaction mixture. Alkyl alcohol is removed from the reaction mixture, and the reaction mixture becomes substantially clear.
Compounds and methods of use
The present invention provides compounds useful in treating or preventing inflammation, acne, bacterial conditions and promoting the appearance of healthy skin and compositions including these compounds.
Compounds and methods of use
The present invention provides compounds useful in treating or preventing inflammation, acne, bacterial conditions and promoting the appearance of healthy skin and compositions including these compounds.
N-ACYL-TYROSINE DERIVATIVES AND USES THEREOF
Provided herein are compounds of Formula A, methods for the preparation thereof, and uses thereof for treating or preventing bacterial infections.
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N-ACYL-TYROSINE DERIVATIVES AND USES THEREOF
Provided herein are compounds of Formula A, methods for the preparation thereof, and uses thereof for treating or preventing bacterial infections.
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Composition of lipoamino acids and alkanediols, process for the preparation thereof, and cosmetic or pharmaceutical composition resulting therefrom
Disclosed are a new composition of lipoamino acids and alkanediols, a process for the preparation thereof, and a cosmetic or pharmaceutical composition resulting therefrom.
Composition of lipoamino acids and alkanediols, process for the preparation thereof, and cosmetic or pharmaceutical composition resulting therefrom
Disclosed are a new composition of lipoamino acids and alkanediols, a process for the preparation thereof, and a cosmetic or pharmaceutical composition resulting therefrom.
Compositions and methods for treating atherosclerotic cardiovascular disease
The present invention relates to lyso-diacylglyceryltrimethylhomoserine (lyso-DGTS) or derivatives thereof for use in the treatment of atherosclerotic cardiovascular disease, and further provides particular such lyso-DGTS derivatives.
Synthesis of (2S,3R,4R)-4,5-dihydroxyisoleucine and derivatives
The invention relates to a method for the preparation of a 4,5-dihydroxyisoleucine derivative comprising the steps of asymmetric Claisen rearrangement of a Z-aminocrotyl-glycin ester and subsequent kinetic resolution of the product diastereomer mix by acylase, and subsequent Sharpless dihydroxylation of the resulting 2-amino-3-methylpent-4-enoic acid derivative.