C07C251/38

Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing such molecules, and processes of using such molecules and compositions against such pests. These molecules and compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (Formula One). ##STR00001##

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure:

##STR00001##

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure:

##STR00001##

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure

##STR00001##

wherein R.sub.1 and R.sub.2 are each independently for each occurrence optionally substituted C.sub.10-C.sub.30alkyl, optionally substituted C.sub.10-C.sub.30alkenyl, optionally substituted C.sub.10-C.sub.30alkynyl, optionally substituted C.sub.10-C.sub.30acyl, or -linker-ligand; R3 is H, optionally substituted C.sub.1-C.sub.10alkyl, optionally substituted C.sub.2-C.sub.10alkenyl, optionally substituted C.sub.2-C.sub.10alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, -aminoalkyls, -(substituted)aminoalkyls, -phosphoalkyls, -thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; E is O, S, N(Q), C(O), N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), S(O), NS(O).sub.2N(Q), S(O).sub.2, N(Q)S(O).sub.2, SS, ON, aryl, heteroaryl, cyclic or heterocycle; and, Q is H, alkyl, -aminoalkyl, -(substituted)aminoalky, -phosphoalkyl or -thiophosphoalkyl.

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure

##STR00001##

wherein R.sub.1 and R.sub.2 are each independently for each occurrence optionally substituted C.sub.10-C.sub.30alkyl, optionally substituted C.sub.10-C.sub.30alkenyl, optionally substituted C.sub.10-C.sub.30alkynyl, optionally substituted C.sub.10-C.sub.30acyl, or -linker-ligand; R3 is H, optionally substituted C.sub.1-C.sub.10alkyl, optionally substituted C.sub.2-C.sub.10alkenyl, optionally substituted C.sub.2-C.sub.10alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, -aminoalkyls, -(substituted)aminoalkyls, -phosphoalkyls, -thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; E is O, S, N(Q), C(O), N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), S(O), NS(O).sub.2N(Q), S(O).sub.2, N(Q)S(O).sub.2, SS, ON, aryl, heteroaryl, cyclic or heterocycle; and, Q is H, alkyl, -aminoalkyl, -(substituted)aminoalky, -phosphoalkyl or -thiophosphoalkyl.

METHODS OF PRODUCING MOLINDONE AND ITS SALTS

The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.

METHODS OF PRODUCING MOLINDONE AND ITS SALTS

The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.

Metal precursor and metal precursor ink using the same
09873662 · 2018-01-23 · ·

Provided are a metal precursor containing an oxime group, which is represented by general formula 1, and a metal precursor ink containing same. The metal precursor ink according to the present invention enhance metal content, induce intramolecular and/or intermolecular complexation, thereby enabling low temperature sintering with excellent solubility and stability. The metal precursor ink according to the present invention can be used to form a metal wire with a desired shape. Therefore, the metal precursor ink can find applications in the field of printed electronics, particularly various electrodes, such as mesh type transparent electrodes.

Metal precursor and metal precursor ink using the same
09873662 · 2018-01-23 · ·

Provided are a metal precursor containing an oxime group, which is represented by general formula 1, and a metal precursor ink containing same. The metal precursor ink according to the present invention enhance metal content, induce intramolecular and/or intermolecular complexation, thereby enabling low temperature sintering with excellent solubility and stability. The metal precursor ink according to the present invention can be used to form a metal wire with a desired shape. Therefore, the metal precursor ink can find applications in the field of printed electronics, particularly various electrodes, such as mesh type transparent electrodes.

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure

##STR00001##

wherein: R.sub.1 and R.sub.2 are each independently for each occurrence optionally substituted C.sub.10-C.sub.30 alkyl, optionally substituted C.sub.10-C.sub.30 alkenyl, optionally substituted C.sub.10-C.sub.30 alkynyl, optionally substituted C.sub.10-C.sub.30 acyl, or -linker-ligand; R.sub.3 is H, optionally substituted C.sub.1-C.sub.10 alkyl, optionally substituted C.sub.2-C.sub.10 alkenyl, optionally substituted C.sub.2-C.sub.10 alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, -aminoalkyls, -(substituted)aminoalkyls, -phosphoalkyls, -thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; and E is C(O)O or OC(O).